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Phenformin

Phenformin is an antidiabetic drug from the biguanide class. It was marketed as DBI by Ciba-Geigy, but was withdrawn from most markets in the late 1970s due to a high risk of lactic acidosis, which was fatal in 50% of cases.

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Research & Products

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Research this topic

Explore the main themes, entities and connections around Phenformin. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Antiviral activity

9 related topics

Research

5 related topics

Toxicity

2 related topics

Chemistry and pharmacokinetics

1 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
International Drug Names
ATC code
A10BA01 (WHO)
CAS Number
114-86-3 Y
ChEBI
CHEBI:8064 N
ChEMBL
ChEMBL170988 Y

Topics to explore

A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Toxicity

Chemistry and pharmacokinetics

  • Log P Octanol-water partition coefficient

Research

Antiviral activity

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.

Phenformin

Nodes27
Edges26
Triples62
Avg. degree1.93
Density0.074074
Components1

How this topic connects Entity context

Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.

See the strongest relationship patterns around the current topic before diving into the raw triples.

Phenformin

Top relations

related to Toxicity · 26
Phenformin → As, Brazil, But, By October, China, Chinese, Ciba-Geigy Corp, Drug Administration, Endocrinology, FDA, Food, Greece, Group, In, In Hong Kong, Italy, July, May, Metabolism Advisory Committee, November
related to Antiviral activity · 7
Phenformin → By, It, NADH, SARS-CoV-2, Syrian, These, Using
related to Research · 6
Phenformin → AMPK, ATP, It, Laboratory, TCA, Vladimir Dilman
related to Chemistry and pharmacokinetics · 5
Phenformin → Following, Its, Plasma, The, Up
3D model (JSmol) · 1
Phenformin → Interactive image
AHFS/Drugs.com · 1
Phenformin → International Drug Names
ATC code · 1
Phenformin → A10BA01 (WHO)
CAS Number · 1
Phenformin → 114-86-3 Y
ChEBI · 1
Phenformin → CHEBI:8064 N
ChEMBL · 1
Phenformin → ChEMBL170988 Y

Important terminology Word statistics

Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

drug lactic acidosis metformin 50 cases oral 15 fda plasma effects antiviral activity administration studies may patients taking citation needed

Entity relationships Subject–Predicate–Object triples

Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.
SubjectPredicateObjectConfidenceSrc
Phenformin3D model (JSmol)Interactive image1.00infobox
PhenforminAHFS/Drugs.comInternational Drug Names1.00infobox
PhenforminATC codeA10BA01 (WHO)1.00infobox
PhenforminCAS Number114-86-3 Y1.00infobox
PhenforminChEBICHEBI:8064 N1.00infobox
PhenforminChEMBLChEMBL170988 Y1.00infobox
PhenforminChemSpider7953 Y1.00infobox
PhenforminCompTox Dashboard (EPA)DTXSID10234491.00infobox
PhenforminDrugBankDB00914 Y1.00infobox
PhenforminECHA InfoCard100.003.6891.00infobox
PhenforminFormulaC10H15N51.00infobox
PhenforminKEGGD08351 Y1.00infobox
PhenforminMelting point175 to 178 °C (347 to 352 °F)1.00infobox
PhenforminMolar mass205.265 g·mol−11.00infobox
PhenforminPubChem CID82491.00infobox
PhenforminRoutes of administrationOral1.00infobox
PhenforminUNIIDD5K7529CE1.00infobox
Phenforminis aantidiabetic drug from the biguanide class0.90text

Related concept clusters Concept neighborhoods

Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridge nodes connect otherwise separate parts of the map. Expand a row to inspect the topic groups on each side.

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

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