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Phenformin: Research & Products

Phenformin is an antidiabetic drug from the biguanide class. It was marketed as DBI by Ciba-Geigy, but was withdrawn from most markets in the late 1970s due to a high risk of lactic acidosis, which was fatal in 50% of cases.

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Phenformin topic overview

The analysis highlights Research and Products as prominent areas in the source structure around Phenformin.

Related topics
21
Source areas
5
Connected nodes
26
Extracted relationships
62
Concept neighborhoods
11
Bridge connections
26

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Antiviral activity · 9 topics
Research · 5 topics
Overview · 4 topics
Toxicity · 2 topics
Chemistry and pharmacokinetics · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
International Drug Names
ATC code
A10BA01 (WHO)
CAS Number
114-86-3 Y
ChEBI
CHEBI:8064 N
ChEMBL
ChEMBL170988 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Toxicity

Chemistry and pharmacokinetics

  • Log P Octanol-water partition coefficient

Research

Antiviral activity

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Phenformin connects Entity context

The extracted context around Phenformin shows recurring relationship patterns in the source. For example, Phenformin → As, Brazil, But, By October, China, Chinese, Ciba-Geigy Corp, Drug Administration, Endocrinology, FDA, Food, Greece, Group, In, In Hong Kong, Italy, July, May, Metabolism Advisory Committee, November Another extracted example is Phenformin → By, It, NADH, SARS-CoV-2, Syrian, These, Using. Use these groups to spot repeated connection types before inspecting the individual relationships.

Phenformin

Top relations

related to Toxicity · 26
Phenformin → As, Brazil, But, By October, China, Chinese, Ciba-Geigy Corp, Drug Administration, Endocrinology, FDA, Food, Greece, Group, In, In Hong Kong, Italy, July, May, Metabolism Advisory Committee, November
related to Antiviral activity · 7
Phenformin → By, It, NADH, SARS-CoV-2, Syrian, These, Using
related to Research · 6
Phenformin → AMPK, ATP, It, Laboratory, TCA, Vladimir Dilman
related to Chemistry and pharmacokinetics · 5
Phenformin → Following, Its, Plasma, The, Up
3D model (JSmol) · 1
Phenformin → Interactive image
AHFS/Drugs.com · 1
Phenformin → International Drug Names
ATC code · 1
Phenformin → A10BA01 (WHO)
CAS Number · 1
Phenformin → 114-86-3 Y
ChEBI · 1
Phenformin → CHEBI:8064 N
ChEMBL · 1
Phenformin → ChEMBL170988 Y

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

drug lactic acidosis metformin 50 cases oral 15 fda plasma effects antiviral activity administration studies may patients taking citation needed

Phenformin relationships Subject–Predicate–Object triples

TTTA extracted 62 structured relationships around Phenformin. Examples in this analysis include Phenformin → 3D model (JSmol) → Interactive image and Phenformin → AHFS/Drugs.com → International Drug Names. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Phenformin3D model (JSmol)Interactive image1.00infobox
PhenforminAHFS/Drugs.comInternational Drug Names1.00infobox
PhenforminATC codeA10BA01 (WHO)1.00infobox
PhenforminCAS Number114-86-3 Y1.00infobox
PhenforminChEBICHEBI:8064 N1.00infobox
PhenforminChEMBLChEMBL170988 Y1.00infobox
PhenforminChemSpider7953 Y1.00infobox
PhenforminCompTox Dashboard (EPA)DTXSID10234491.00infobox
PhenforminDrugBankDB00914 Y1.00infobox
PhenforminECHA InfoCard100.003.6891.00infobox
PhenforminFormulaC10H15N51.00infobox
PhenforminKEGGD08351 Y1.00infobox
PhenforminMelting point175 to 178 °C (347 to 352 °F)1.00infobox
PhenforminMolar mass205.265 g·mol−11.00infobox
PhenforminPubChem CID82491.00infobox
PhenforminRoutes of administrationOral1.00infobox
PhenforminUNIIDD5K7529CE1.00infobox
Phenforminis aantidiabetic drug from the biguanide class0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Phenformin bring nearby vocabulary together. In this analysis, examples include Metformin, Lactic and Administration. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Phenformin
    • Metformin
    • Lactic
    • Administration
    • Citation
    • Needed
    • Studies
    • Taking
    • Melting
    • Model
    • Point
    • May
    • Patients
  • phenformin
    • Metformin
    • Lactic
    • Administration
    • Citation
    • Needed
    • Studies
    • Taking
    • Melting
    • Model
    • Point
    • May
    • Patients
  • antiviral activity
    • Model
    • Activity
    • Antiviral
    • Studies
    • Dengue
    • Drugs
    • Due
    • Melting
    • Point
    • Research
    • Sars-cov-2
    • Showed
  • antidiabetic drug
    • Drugs
    • Phenformin
    • Research
    • Administration
    • Fda
    • Acidosis
    • Lactic
    • Due
    • Melting
    • Metabolism
    • Model
    • Point
  • lactic acidosis
    • Lactic
    • Cases
    • Due
    • Phenformin
    • Drug
    • Ciba-geigy
    • Drugs
    • Melting
    • Model
    • Point
    • Research
    • Activity
  • metformin
    • Citation
    • May
    • Needed
    • Studies
    • Phenformin
    • Point
    • Patients
    • Taking
    • Plasma
  • virus
    • Dengue
    • Sars-cov-2
    • Metabolism
    • Model
    • Showed
    • Antiviral
    • Effects
    • Phenformin
  • dengue
    • Sars-cov-2
    • Virus
    • Metabolism
    • Model
    • Showed
    • Effects
    • Phenformin

Connections between topic areas Semantic bridges

For Phenformin, one of the stronger structural bridges in this analysis connects Phenformin with Antiviral activity. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
PhenforminAntiviral activity · splits 17 ⟂ 10
PhenforminResearch · splits 21 ⟂ 6
PhenforminOverview · splits 22 ⟂ 5
PhenforminToxicity · splits 24 ⟂ 3

Map overview Semantic statistics

Phenformin

Nodes27
Edges26
Triples62
Avg. degree1.93
Density0.074074
Components1

Source & methodology

TTTA analyzes the structure around Phenformin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Research & Products, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Phenformin · EN edition · Analysis: TopicsToTalkAbout

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