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BOP1

Ribosome biogenesis protein BOP1 is a protein that in humans is encoded by the BOP1 gene. It is a WD40 repeat-containing nucleolar protein involved in rRNA processing, thereby controlling the cell cycle. It is required for the maturation of the 25S and 5.8S ribosomal RNAs. It may serve as an essential factor in ribosome formation that coordinates…

Function, Structure & Overview

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BOP1 at a glance

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Function

17 related topics

Structure

1 related topic

Overview

7 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
BOP1, block of proliferation 1, BOP1 ribosomal biogenesis factor
Band
8q24.3 · 15 D3|15 35.91 cM
Bgee
right lobe of thyroid gland · right hemisphere of cerebellum · left lobe of thyroid gland · pituitary gland · anterior pituitary
BioGPS
More reference expression data
Chr.
Chromosome 8 (human) · Chromosome 15 (mouse)
Databases
NCBI: entry; OMA: entry

Topics to explore

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Overview

Function

Structure

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How this topic connects Entity context

Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.

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BOP1

Top relations

Bgee · 19
BOP1 → anterior pituitary, apex of heart, embryo, epiblast, gastrocnemius muscle, left lobe of thyroid gland, mandibular prominence, mucosa of transverse colon, otic placode, otic vesicle, pituitary gland, primitive streak, right frontal lobe, right hemisphere of cerebellum, right lobe of thyroid gland, right uterine tube, saccule, somite, yolk sac
Gene ontology · 19
BOP1 → cell population proliferation, cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), nucleolus, nucleoplasm, nucleus, PeBoW complex, preribosome, large subunit precursor, protein binding, regulation of cell cycle, regulation of signal transduction by p53 class mediator, ribonucleoprotein complex, ribonucleoprotein complex binding, ribosomal large subunit assembly, ribosomal large subunit biogenesis, ribosome biogenesis, RNA binding, rRNA processing
RNA expression pattern · 19
BOP1 → anterior pituitary, apex of heart, embryo, epiblast, gastrocnemius muscle, left lobe of thyroid gland, mandibular prominence, mucosa of transverse colon, otic placode, otic vesicle, pituitary gland, primitive streak, right frontal lobe, right hemisphere of cerebellum, right lobe of thyroid gland, right uterine tube, saccule, somite, yolk sac
related to Function · 14
BOP1 → Bop1/Pes1, Bop1/WDR12, Deregulation, Elevated, GRWD1, In Giardia, Nop7p-Erb1p-Ytm1p, ORC6L, PeBoW, PES1, Pes1-Bop1-WDR12, RPL3, The, The Pes1-Bop1
Band · 2
BOP1 → 15 D3|15 35.91 cM, 8q24.3
Chr. · 2
BOP1 → Chromosome 15 (mouse), Chromosome 8 (human)
End · 2
BOP1 → 144,291,438 bp, 76,361,477 bp
related to External links · 2
BOP1 → Human BOP1, UCSC Genome Browser
related to Structure · 2
BOP1 → BOP1NT, N-terminal
Aliases · 1
BOP1 → BOP1, block of proliferation 1, BOP1 ribosomal biogenesis factor

Important terminology Word statistics

Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.

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Important terminology

biogenesis human ribosome bp protein gene chr band chromosome complex location processing ribosomal cell involved proliferation mouse humans pebow rrna

Entity relationships Subject–Predicate–Object triples

Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.
SubjectPredicateObjectConfidenceSrc
BOP1AliasesBOP1, block of proliferation 1, BOP1 ribosomal biogenesis factor1.00infobox
BOP1Band8q24.31.00infobox
BOP1Band15 D3|15 35.91 cM1.00infobox
BOP1Bgeeright lobe of thyroid gland1.00infobox
BOP1Bgeeright hemisphere of cerebellum1.00infobox
BOP1Bgeeleft lobe of thyroid gland1.00infobox
BOP1Bgeepituitary gland1.00infobox
BOP1Bgeeanterior pituitary1.00infobox
BOP1Bgeeright uterine tube1.00infobox
BOP1Bgeegastrocnemius muscle1.00infobox
BOP1Bgeeright frontal lobe1.00infobox
BOP1Bgeemucosa of transverse colon1.00infobox
BOP1Bgeeapex of heart1.00infobox
BOP1Bgeeotic placode1.00infobox
BOP1Bgeesaccule1.00infobox
BOP1Bgeeotic vesicle1.00infobox
BOP1Bgeeepiblast1.00infobox
BOP1Bgeesomite1.00infobox
BOP1Bgeeembryo1.00infobox
BOP1Bgeeyolk sac1.00infobox
BOP1Bgeeprimitive streak1.00infobox
BOP1Bgeemandibular prominence1.00infobox
BOP1BioGPSMore reference expression data1.00infobox
BOP1Chr.Chromosome 8 (human)1.00infobox
BOP1Chr.Chromosome 15 (mouse)1.00infobox
BOP1DatabasesNCBI: entry; OMA: entry1.00infobox
BOP1End144,291,438 bp1.00infobox
BOP1End76,361,477 bp1.00infobox
BOP1EnsemblENSG00000261236 ENSG000002853011.00infobox
BOP1Entrez232461.00infobox

Related concept clusters Concept neighborhoods

Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.

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    Connections between topic areas Semantic bridges

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    Map overview Semantic statistics

    Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.

    BOP1

    Nodes29
    Edges28
    Triples96
    Avg. degree1.93
    Density0.068966
    Components1
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