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BLOSUM

In bioinformatics, the BLOSUM (BLOcks SUbstitution Matrix) matrix is a substitution matrix used for sequence alignment of proteins. BLOSUM matrices are used to score alignments between evolutionarily divergent protein sequences. They are based on local alignments. BLOSUM matrices were first introduced in a paper by Steven Henikoff and Jorja Henikoff.…

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Overview

BioinformaticsSubstitution matrixSequence alignmentProteinsEvolutionarily divergent
17 related topics

Biological background

CellCell divisionMutationGenetic codeHomology
6 related topics

Some uses in bioinformatics

BLASTNCBI
2 related topics

Construction of BLOSUM matrices

Logarithm
1 related topics

Topics to explore

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Overview

Biological background

Construction of BLOSUM matrices

Variants

Some uses in bioinformatics

Advanced semantic analysis

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Map overview Semantic statistics

BLOSUM

Nodes33
Edges32
Triples77
Avg. degree1.94
Density0.060606
Components1

How this topic connects Entity context

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BLOSUM

Top relations

related to External links · 16
BLOSUM → Archived, BLAST, BLOCKS WWW, BLOSUM30, BLOSUM62, Eddy, Interactive BLOSUM Network Visualization, January, Nature Biotechnology, NCBI FTP, NCBIData, PMID, S2CID, Sean, Wayback Machine, Where
related to Availability · 11
BLOSUM → APIs, BLOSUM45, BLOSUM50, BLOSUM62, BLOSUM80, BLOSUM90, Both, NCBI, The, This, Toolkit
related to Score of the BLOSUM matrices · 10
BLOSUM → All, Both, But, Commonly, PAM, Substitution, The, Thus, Two, Typically
related to Terminology · 10
BLOSUM → BLAST, BLOSUM-62, BLOSUM45, BLOSUM62, BLOSUM80, Experimentation, For, Note, Several, The
related to PMB · 8
BLOSUM → Blocks, BLOSUM's, It, JTT, PAM, PMB, Probability Matrix, The
related to RBLOSUM · 8
BLOSUM → BLOSUM62, CorBLOSUM, Henikoff, RBLOSUM, RBLOSUM64, Surprisingly, The, The BLOSUM62
related to Calculating Frequency & Probability · 3
BLOSUM → By, Only, These
related to CorBLOSUM · 3
BLOSUM → CorBLOSUM, RBLOSUM, The
related to Use in BLAST · 3
BLOSUM → BLAST, DNA, This
related to BLOSUM · 2
BLOSUM → BLOSUM62, BLOSUM80

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Important terminology

matrices sequences used matrix amino alignment protein substitution proteins acids score blocks sequence pam alignments two different related based mutation

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
BLOSUMhas applicationT-cell0.60section
BLOSUMrelated to AvailabilityThe0.60section
BLOSUMrelated to AvailabilityNCBI0.60section
BLOSUMrelated to AvailabilityBoth0.60section
BLOSUMrelated to AvailabilityToolkit0.60section
BLOSUMrelated to AvailabilityBLOSUM450.60section
BLOSUMrelated to AvailabilityBLOSUM500.60section
BLOSUMrelated to AvailabilityBLOSUM620.60section
BLOSUMrelated to AvailabilityBLOSUM800.60section
BLOSUMrelated to AvailabilityBLOSUM900.60section
BLOSUMrelated to AvailabilityAPIs0.60section
BLOSUMrelated to AvailabilityThis0.60section

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