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Azurin: Disease relevance, Biological function & Overview

Azurin is a small, periplasmic, bacterial blue copper protein found in Pseudomonas, Bordetella, or Alcaligenes bacteria. Azurin moderates single-electron transfer between enzymes associated with the cytochrome chain by undergoing oxidation-reduction between Cu(I) and Cu(II). Each monomer of an azurin tetramer has a molecular weight of approximately…

Language: English [EN]
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Azurin topic overview

The analysis highlights Disease relevance, Biological function and Overview as prominent areas in the source structure around Azurin.

Related topics
29
Source areas
5
Connected nodes
34
Extracted relationships
36
Concept neighborhoods
16
Bridge connections
34

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 13 topics
Disease relevance · 8 topics
Biological function · 5 topics
Protein structure · 2 topics
Protein function · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
PF00127
Available protein structures:
PF00127
CDD
cd13922
PDB
PF00127 (ECOD; PDBsum)
Pfam
PF00127
SCOP2
5azu / SCOPe / SUPFAM

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Protein function

Protein structure

Biological function

Disease relevance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Azurin connects Entity context

The extracted context around Azurin shows recurring relationship patterns in the source. For example, Azurin → Cu, Cys112, Gly45, His117, His46, II, Met121, Once, Structurally, The, With Another extracted example is Azurin → Although, Bax, E3, Four, G1, In, Noxa, P53, The. Use these groups to spot repeated connection types before inspecting the individual relationships.

Azurin

Top relations

related to Protein structure · 11
Azurin → Cu, Cys112, Gly45, His117, His46, II, Met121, Once, Structurally, The, With
related to Disease relevance · 9
Azurin → Although, Bax, E3, Four, G1, In, Noxa, P53, The
related to Protein function · 4
Azurin → Az, Cu2, In, The
related to Biological function · 2
Azurin → Azurins, When
AlphaFold · 1
Azurin → PF00127
Available protein structures: · 1
Azurin → PF00127
CDD · 1
Azurin → cd13922
PDB · 1
Azurin → PF00127 (ECOD; PDBsum)
Pfam · 1
Azurin → PF00127
SCOP2 · 1
Azurin → 5azu / SCOPe / SUPFAM

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein copper cytochrome p53 blue pseudomonas cancer redox c551 aeruginosa hydrophobic residues interaction also bacteria electron potential azurin's demonstrated effects

Azurin relationships Subject–Predicate–Object triples

TTTA extracted 36 structured relationships around Azurin. Examples in this analysis include Azurin → AlphaFold → PF00127 and Azurin → CDD → cd13922. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
AzurinAlphaFoldPF001271.00infobox
AzurinAvailable protein structures:PF001271.00infobox
AzurinCDDcd139221.00infobox
AzurinPDBPF00127 (ECOD; PDBsum)1.00infobox
AzurinPfamPF001271.00infobox
AzurinSCOP25azu / SCOPe / SUPFAM1.00infobox
AzurinSymbolCopper-bind1.00infobox
Azurinis asmall0.90text
EphB2 receptorsinstance ofthe USFDA approved the designation of p28 as an orphan drug for glioma.Azurin's other domains may also exhibit strong anticancer activity by binding to cell surface receptor tyr…0.80text
which induce angiogenesis in cancer cellsinstance ofthe USFDA approved the designation of p28 as an orphan drug for glioma.Azurin's other domains may also exhibit strong anticancer activity by binding to cell surface receptor tyr…0.80text
Azurinrelated to Biological functionWhen0.60section
Azurinrelated to Biological functionAzurins0.60section

Related concept clusters Concept neighborhoods

The concept neighborhoods around Azurin bring nearby vocabulary together. In this analysis, examples include Protein, P53 and Electron. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Azurin
    • Protein
    • P53
    • Electron
    • Cancer
    • Copper
    • Although
    • Interaction
    • Transfer
    • Blue
    • Potential
    • Cytochrome
    • Redox
  • azurin
    • Protein
    • P53
    • Electron
    • Cancer
    • Copper
    • Although
    • Interaction
    • Transfer
    • Blue
    • Potential
    • Cytochrome
    • Redox
  • copper protein
    • Atom
    • Ligands
    • Aeruginosa
    • Hydrophobic
    • Potential
    • Pseudomonas
    • Residues
    • Electron
    • Redox
    • P53
    • Protein
    • Found
  • protein function
    • Aeruginosa
    • Pseudomonas
    • Electron
    • P53
    • Tetramer
    • Although
    • Anticancer
    • C551
    • Cu
    • Ii
    • Interaction
    • Structural
  • protein structure
    • Aeruginosa
    • Pseudomonas
    • Electron
    • P53
    • Tetramer
    • Although
    • Anticancer
    • C551
    • Cu
    • Ii
    • Interaction
    • Structural
  • cytochrome c551
    • C551
    • Cytochrome
    • Aeruginosa
    • Nitrite
    • Denitrification
    • Interaction
    • Pseudomonas
    • Site
    • Hydrophobic
    • Residues
    • Cu
    • Ii
  • cu(i) and cu(ii)
    • Ii
    • Although
    • Atom
    • Ligands
    • Structural
    • Transfer
    • Also
    • Azurin's
    • Demonstrated
    • Hydrophobic
    • Potential
    • Residues
  • cytochrome
    • C551
    • Aeruginosa
    • Nitrite
    • Denitrification
    • Cu
    • Ii
    • Interaction
    • Pseudomonas
    • Site
    • Transfer
    • Well
    • Hydrophobic

Connections between topic areas Semantic bridges

For Azurin, one of the stronger structural bridges in this analysis connects Azurin with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
AzurinOverview · splits 21 ⟂ 14
AzurinDisease relevance · splits 26 ⟂ 9
AzurinBiological function · splits 29 ⟂ 6
AzurinProtein structure · splits 32 ⟂ 3

Map overview Semantic statistics

Azurin

Nodes35
Edges34
Triples36
Avg. degree1.94
Density0.057143
Components1

Source & methodology

TTTA analyzes the structure around Azurin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Disease relevance, Biological function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Azurin · EN edition · Analysis: TopicsToTalkAbout

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