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Azurin

Azurin is a small, periplasmic, bacterial blue copper protein found in Pseudomonas, Bordetella, or Alcaligenes bacteria. Azurin moderates single-electron transfer between enzymes associated with the cytochrome chain by undergoing oxidation-reduction between Cu(I) and Cu(II). Each monomer of an azurin tetramer has a molecular weight of approximately…

Disease relevance, Biological function & Overview

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AlphaFold
PF00127
Available protein structures:
PF00127
CDD
cd13922
PDB
PF00127 (ECOD; PDBsum)
Pfam
PF00127
SCOP2
5azu / SCOPe / SUPFAM

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Overview

Protein function

Protein structure

Biological function

Disease relevance

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Map overview Semantic statistics

Azurin

Nodes35
Edges34
Triples36
Avg. degree1.94
Density0.057143
Components1

How this topic connects Entity context

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Azurin

Top relations

related to Protein structure · 11
Azurin → Cu, Cys112, Gly45, His117, His46, II, Met121, Once, Structurally, The, With
related to Disease relevance · 9
Azurin → Although, Bax, E3, Four, G1, In, Noxa, P53, The
related to Protein function · 4
Azurin → Az, Cu2, In, The
related to Biological function · 2
Azurin → Azurins, When
AlphaFold · 1
Azurin → PF00127
Available protein structures: · 1
Azurin → PF00127
CDD · 1
Azurin → cd13922
PDB · 1
Azurin → PF00127 (ECOD; PDBsum)
Pfam · 1
Azurin → PF00127
SCOP2 · 1
Azurin → 5azu / SCOPe / SUPFAM

Important terminology Word statistics

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Important terminology

protein copper cytochrome p53 blue pseudomonas cancer redox c551 aeruginosa hydrophobic residues interaction also bacteria electron potential azurin's demonstrated effects

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
AzurinAlphaFoldPF001271.00infobox
AzurinAvailable protein structures:PF001271.00infobox
AzurinCDDcd139221.00infobox
AzurinPDBPF00127 (ECOD; PDBsum)1.00infobox
AzurinPfamPF001271.00infobox
AzurinSCOP25azu / SCOPe / SUPFAM1.00infobox
AzurinSymbolCopper-bind1.00infobox
Azurinis asmall0.90text
EphB2 receptorsinstance ofthe USFDA approved the designation of p28 as an orphan drug for glioma.Azurin's other domains may also exhibit strong anticancer activity by binding to cell surface receptor tyr…0.80text
which induce angiogenesis in cancer cellsinstance ofthe USFDA approved the designation of p28 as an orphan drug for glioma.Azurin's other domains may also exhibit strong anticancer activity by binding to cell surface receptor tyr…0.80text
Azurinrelated to Biological functionWhen0.60section
Azurinrelated to Biological functionAzurins0.60section

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    Min side: 3
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