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Azalide

Azalides are a class of macrolide antibiotics that were originally manufactured in response to the poor acid stability exhibited by original macrolides such as erythromycin. Examples of azalides include azithromycin, which is used in humans, while tulathromycin and gamithromycin are used in veterinary medicine. Following the clinical overuse of…

Mechanism of action, Structure & Pharmacokinetics

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Overview

Structure

Mechanism of action

Pharmacokinetics

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Map overview Semantic statistics

Azalide

Nodes18
Edges17
Triples13
Avg. degree1.89
Density0.111111
Components1

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Azalide

Top relations

related to Pharmacokinetics · 4
Azalide → Applicable, AUC24/MIC, Due, MIC
related to Structure · 3
Azalide → Azalides, Replacement, See Beckmann
related to Mechanism of action · 2
Azalide → Azalides, RNA

Important terminology Word statistics

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Important terminology

azalides stability macrolides acid erythromycin azithromycin macrolide effect structure tulathromycin gamithromycin ketolides cyp3a4 pharmacokinetic greater class antibiotics originally manufactured response

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
erythromycininstance ofAzalides are a class of macrolide antibiotics that were originally manufactured in response to the poor acid stability exhibited by original macrolides0.80text
more potent gram negative antimicrobial activityinstance ofAzalides have several advantages over erythromycin0.80text
acid stabilityinstance ofAzalides have several advantages over erythromycin0.80text
and side effect tolerabilityinstance ofAzalides have several advantages over erythromycin0.80text
Azaliderelated to Mechanism of actionAzalides0.60section
Azaliderelated to Mechanism of actionRNA0.60section
Azaliderelated to PharmacokineticsApplicable0.60section
Azaliderelated to PharmacokineticsAUC24/MIC0.60section
Azaliderelated to PharmacokineticsMIC0.60section
Azaliderelated to PharmacokineticsDue0.60section
Azaliderelated to StructureAzalides0.60section
Azaliderelated to StructureReplacement0.60section

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    Min side: 3
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