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Irbesartan

Irbesartan, sold under the brand name Aprovel among others, is a medication used to treat hypertension (high blood pressure), heart failure, and diabetic kidney disease. It is a reasonable initial treatment for high blood pressure. It is taken by mouth. Versions are available as the combination irbesartan/hydrochlorothiazide.

History, Community, Culture & Applications

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Topic orientation

Irbesartan at a glance

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Explore the main themes, entities and connections around Irbesartan. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
C09CA04 (WHO) C09DA04 (WHO)
Bioavailability
60% to 80%
CAS Number
138402-11-6 Y
ChEBI
CHEBI:5959 Y

Topics to explore

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Overview

Medical uses

Side effects

Mechanism of action

History

Society and culture

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How this topic connects Entity context

Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.

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Irbesartan

Top relations

related to history · 9
Irbesartan → Aprovel, Avapro, Bristol-Myers Squibb, In, It, Karvea, Sanofi Research, Sanofi-Aventis, United States
related to Recalls · 8
Irbesartan → Drug Administration, FDA, Health Canada, II, In, September, The FDA, US Food
Legal status · 5
Irbesartan → AU: S4 (Prescription only), EU: Rx-only, In general: ℞ (Prescription only), UK: POM (Prescription only), US: ℞-only
3D model (JSmol) · 1
Irbesartan → Interactive image
AHFS/Drugs.com · 1
Irbesartan → Monograph
ATC code · 1
Irbesartan → C09CA04 (WHO) C09DA04 (WHO)
Bioavailability · 1
Irbesartan → 60% to 80%
CAS Number · 1
Irbesartan → 138402-11-6 Y
ChEBI · 1
Irbesartan → CHEBI:5959 Y
ChEMBL · 1
Irbesartan → ChEMBL1513 Y

Important terminology Word statistics

Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.

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Important terminology

blood pressure kidney effects combination aprovel hypertension medication available high nitrosamine side hydrochlorothiazide name others mouth may also impurities brand

Entity relationships Subject–Predicate–Object triples

Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.
SubjectPredicateObjectConfidenceSrc
Irbesartan3D model (JSmol)Interactive image1.00infobox
IrbesartanAHFS/Drugs.comMonograph1.00infobox
IrbesartanATC codeC09CA04 (WHO) C09DA04 (WHO)1.00infobox
IrbesartanBioavailability60% to 80%1.00infobox
IrbesartanCAS Number138402-11-6 Y1.00infobox
IrbesartanChEBICHEBI:5959 Y1.00infobox
IrbesartanChEMBLChEMBL1513 Y1.00infobox
IrbesartanChemSpider3618 Y1.00infobox
IrbesartanCompTox Dashboard (EPA)DTXSID00231691.00infobox
IrbesartanDrug classCardiovascular agent1.00infobox
IrbesartanDrugBankDB01029 Y1.00infobox
IrbesartanECHA InfoCard100.119.9661.00infobox
IrbesartanElimination half-life11 h to 15 h1.00infobox
IrbesartanExcretionKidney 20%, feces 65%1.00infobox
IrbesartanFormulaC25H28N6O1.00infobox
IrbesartanIUPHAR/BPS5891.00infobox
IrbesartanKEGGD00523 Y1.00infobox
IrbesartanLegal statusAU: S4 (Prescription only)1.00infobox
IrbesartanLegal statusUK: POM (Prescription only)1.00infobox
IrbesartanLegal statusUS: ℞-only1.00infobox
IrbesartanLegal statusEU: Rx-only1.00infobox
IrbesartanLegal statusIn general: ℞ (Prescription only)1.00infobox
IrbesartanLicense dataUS DailyMed: Irbesartan1.00infobox
IrbesartanMedlinePlusa6980091.00infobox
IrbesartanMetabolismLiver (CYP2C9)1.00infobox
IrbesartanMolar mass428.540 g·mol−11.00infobox
IrbesartanPregnancy categoryAU: D1.00infobox
IrbesartanPronunciation/ɜːrbəˈsɑːrtən/1.00infobox
IrbesartanProtein binding~90%1.00infobox
IrbesartanPubChem CID37491.00infobox

Related concept clusters Concept neighborhoods

Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridge nodes connect otherwise separate parts of the map. Expand a row to inspect the topic groups on each side.

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Map overview Semantic statistics

    Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.

    Irbesartan

    Nodes31
    Edges30
    Triples52
    Avg. degree1.94
    Density0.064516
    Components1
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