ARHGAP11B

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ARHGAP11B topic overview

The analysis highlights Function, Human evolution and Structure as prominent areas in the source structure around ARHGAP11B.

Related topics: 21
Source areas: 5
Connected nodes: 26
Extracted relationships: 64
Concept neighborhoods: 13
Bridge connections: 26

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 8 topics

Human evolution · 7 topics

Overview · 3 topics

Structure · 2 topics

Activity · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: ARHGAP11B, B'-T, FAM7B1, Rho GTPase activating protein 11B, GAP (1-8), ArhGAP11B and human encephalisation
Band: 15q13.2
Bgee: testicle · bone marrow · bone marrow cell · ganglionic eminence · stromal cell of endometrium
BioGPS: n/a
Chr.: Chromosome 15 (human)
Databases: NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

ARHGAP11A ARHGAP11A?action=edit&redlink=1
RhoGAP domain

Activity

Transfection

Function

Human evolution

Genetic factors of recent brain evolution and difference of modern humans to (other) apes and Neanderthals Evolution of the brain
Mutation
Single nucleotide substitution Single-nucleotide polymorphism
Common marmoset
Radial glial cells Radial glial cell
Gyral Gyrus
Sulcus Sulcus (neuroanatomy)

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How ARHGAP11B connects Entity context

The extracted context around ARHGAP11B shows recurring relationship patterns in the source. For example, ARHGAP11B → appendix, bone marrow, bone marrow cell, ganglionic eminence, gonad, lymph node, monocyte, stromal cell of endometrium, testicle, ventricular zone Another extracted example is ARHGAP11B → ARHGAP11A, ARHGAP11A1-220, C-terminal, In, RhoA/Rho-kinase, RhoGAP, This. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Bgee · 10

ARHGAP11B → appendix, bone marrow, bone marrow cell, ganglionic eminence, gonad, lymph node, monocyte, stromal cell of endometrium, testicle, ventricular zone

RNA expression pattern · 10

ARHGAP11B → appendix, bone marrow, bone marrow cell, ganglionic eminence, gonad, lymph node, monocyte, stromal cell of endometrium, testicle, ventricular zone

related to Activity · 7

ARHGAP11B → ARHGAP11A, ARHGAP11A1-220, C-terminal, In, RhoA/Rho-kinase, RhoGAP, This

Gene ontology · 6

ARHGAP11B → cerebral cortex development, cytosol, GTPase activator activity, positive regulation of GTPase activity, regulation of small GTPase mediated signal transduction, signal transduction

related to Function · 5

ARHGAP11B → Furthermore, It, Rho, RhoGAP, Several

related to Structure · 5

ARHGAP11B → ARHGAP11A, C-terminal, GAP, Rho GTPase-activating-protein, RhoGAP

related to Human evolution · 3

ARHGAP11B → Changes, Neanderthals, This

is a · 2

ARHGAP11B → gene responsible for the development of the neocortex during human evolution, human-specific gene that amplifies basal progenitors

Aliases · 1

ARHGAP11B → ARHGAP11B, B'-T, FAM7B1, Rho GTPase activating protein 11B, GAP (1-8), ArhGAP11B and human encephalisation

Band · 1

ARHGAP11B → 15q13.2

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

neocortex human gene activity bp arhgap11a rhogap folding development chr chromosome 15 function likely expansion evolution band rho nucleotide evolutionary

ARHGAP11B relationships Subject–Predicate–Object triples

TTTA extracted 64 structured relationships around ARHGAP11B. Examples in this analysis include ARHGAP11B → Aliases → ARHGAP11B, B'-T, FAM7B1, Rho GTPase activating protein 11B, GAP (1-8), ArhGAP11B and human encephalisation and ARHGAP11B → Band → 15q13.2. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
ARHGAP11B	Aliases	ARHGAP11B, B'-T, FAM7B1, Rho GTPase activating protein 11B, GAP (1-8), ArhGAP11B and human encephalisation	1.00	infobox
ARHGAP11B	Band	15q13.2	1.00	infobox
ARHGAP11B	Bgee	testicle	1.00	infobox
ARHGAP11B	Bgee	bone marrow	1.00	infobox
ARHGAP11B	Bgee	bone marrow cell	1.00	infobox
ARHGAP11B	Bgee	ganglionic eminence	1.00	infobox
ARHGAP11B	Bgee	stromal cell of endometrium	1.00	infobox
ARHGAP11B	Bgee	ventricular zone	1.00	infobox
ARHGAP11B	Bgee	gonad	1.00	infobox
ARHGAP11B	Bgee	lymph node	1.00	infobox
ARHGAP11B	Bgee	monocyte	1.00	infobox
ARHGAP11B	Bgee	appendix	1.00	infobox
ARHGAP11B	BioGPS	n/a	1.00	infobox
ARHGAP11B	Chr.	Chromosome 15 (human)	1.00	infobox
ARHGAP11B	Databases	NCBI: entry; OMA: entry	1.00	infobox
ARHGAP11B	End	30,649,529 bp	1.00	infobox
ARHGAP11B	Ensembl	ENSG00000274734 ENSG00000286139 ENSG00000285077	1.00	infobox
ARHGAP11B	Entrez	89839	1.00	infobox
ARHGAP11B	External IDs	OMIM: 616310; GeneCards: ARHGAP11B	1.00	infobox
ARHGAP11B	Gene location (Human)	Gene location (Human)Chr.Chromosome 15 (human)Band15q13.2Start30,624,494 bpEnd30,649,529 bp	1.00	infobox
ARHGAP11B	Gene ontology	GTPase activator activity	1.00	infobox
ARHGAP11B	Gene ontology	cytosol	1.00	infobox
ARHGAP11B	Gene ontology	regulation of small GTPase mediated signal transduction	1.00	infobox
ARHGAP11B	Gene ontology	signal transduction	1.00	infobox
ARHGAP11B	Gene ontology	cerebral cortex development	1.00	infobox
ARHGAP11B	Gene ontology	positive regulation of GTPase activity	1.00	infobox
ARHGAP11B	Location (UCSC)	Chr 15: 30.62 – 30.65 Mb	1.00	infobox
ARHGAP11B	Orthologs	OrthologsDatabasesNCBI: entry; OMA: entrySpeciesHumanMouseEntrez89839n/aEnsemblENSG00000274734 ENSG00000286139 ENSG00000285077n/aUniProtQ3KRB8n/aRefSeq (mRNA)NM_001039841n/aRefS…	1.00	infobox
ARHGAP11B	RefSeq (mRNA)	NM_001039841	1.00	infobox
ARHGAP11B	RefSeq (protein)	NP_001034930	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around ARHGAP11B bring nearby vocabulary together. In this analysis, examples include Neocortex, Gene and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

ARHGAP11B
- Neocortex
- Gene
- Human
- Arhgap11a
- Activity
- Development
- Evolution
- Expansion
- Function
- Likely
- Rhogap
- Assay
arhgap11b
- Neocortex
- Gene
- Human
- Arhgap11a
- Activity
- Development
- Evolution
- Expansion
- Function
- Likely
- Rhogap
- Assay
gene duplication
- Development
- Human
- Gtpase
- Location
- Protein
- Bp
- Chr
- Chromosome
- Evolution
- Function
- Neocortex
- Activity
activity
- Assay
- Cell
- Gtpase
- Location
- Protein
- Bp
- Chr
- Chromosome
- Function
- Arhgap11a
- Arhgap11b
- Rhogap
human evolution
- Bp
- Chr
- Chromosome
- Band
- Gene
- Gtpase
- Location
- Protein
- Neocortex
- Evolution
- Function
- Human
function
- Gtpase
- Location
- Protein
- Bp
- Chr
- Chromosome
- Gene
- Human
- Acids
- Amino
- Band
- Cell
genetic factors of recent brain evolution and difference of modern humans to (other) apes and neanderthals
- Activating
- Gene
- Mitochondria
- Human
- Evolution
- Gap
- Gtpase
- Location
- Neanderthals
- Protein
- Bp
- Chr
arhgap11a
- Rhogap
- Assay
- C-terminal
- Lysine-220
- Sequence
- Arhgap11b
- Cell
- Encodes
- Found
- Gap
- Rho

Connections between topic areas Semantic bridges

For ARHGAP11B, one of the stronger structural bridges in this analysis connects ARHGAP11B with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

ARHGAP11B — Function · splits 18 ⟂ 9

ARHGAP11B — Human evolution · splits 19 ⟂ 8

ARHGAP11B — Overview · splits 23 ⟂ 4

ARHGAP11B — Structure · splits 24 ⟂ 3

Map overview Semantic statistics

ARHGAP11B

Nodes27

Edges26

Triples64

Avg. degree1.93

Density0.074074

Components1

Source & methodology

TTTA analyzes the structure around ARHGAP11B to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Human evolution & Structure, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — ARHGAP11B · EN edition · Analysis: TopicsToTalkAbout