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APIP: Interactions & Overview

APAF1-interacting protein is a protein that in humans is encoded by the APIP gene. It is an enzyme with Methylthioribulose 1-phosphate dehydratase activity which is involved in the methionine salvage pathway.

Language: English [EN]
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APIP topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around APIP.

Related topics
7
Source areas
2
Connected nodes
9
Extracted relationships
83
Concept neighborhoods
9
Bridge connections
9

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 5 topics
Interactions · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

4.2.1.109
Aliases
APIP, APIP2, CGI29, MMRP19, hCGI-29, APAF1 interacting protein
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4M6R
Band
11p13 · 2|2 E2
Bgee
C1 segment · muscle of thigh · right adrenal gland · corpus callosum · right adrenal cortex
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How APIP connects Entity context

The extracted context around APIP shows recurring relationship patterns in the source. For example, APIP → brown adipose tissue, C1 segment, cardiac muscle tissue of left ventricle, corpus callosum, digastric muscle, gastrocnemius muscle, interventricular septum, left adrenal cortex, left adrenal gland, monocyte, muscle of thigh, right adrenal cortex, right adrenal gland, right kidney, right ventricle, secondary oocyte, skeletal muscle tissue, temporal muscle, zygote Another extracted example is APIP → apoptotic process, cellular amino acid biosynthetic process, cytoplasm, cytosol, identical protein binding, L-methionine salvage from methylthioadenosine, L-methionine salvage from S-adenosylmethionine, lyase activity, metal ion binding, methionine biosynthetic process, methylthioribulose 1-phosphate dehydratase activity, negative regulation of apoptotic process, protein binding, protein homotetramerization, pyroptosis, regulation of ERK1 and ERK2 cascade, zinc ion binding. Use these groups to spot repeated connection types before inspecting the individual relationships.

APIP

Top relations

Bgee · 19
APIP → brown adipose tissue, C1 segment, cardiac muscle tissue of left ventricle, corpus callosum, digastric muscle, gastrocnemius muscle, interventricular septum, left adrenal cortex, left adrenal gland, monocyte, muscle of thigh, right adrenal cortex, right adrenal gland, right kidney, right ventricle, secondary oocyte, skeletal muscle tissue, temporal muscle, zygote
RNA expression pattern · 19
APIP → brown adipose tissue, C1 segment, cardiac muscle tissue of left ventricle, corpus callosum, digastric muscle, gastrocnemius muscle, interventricular septum, left adrenal cortex, left adrenal gland, monocyte, muscle of thigh, right adrenal cortex, right adrenal gland, right kidney, right ventricle, secondary oocyte, skeletal muscle tissue, temporal muscle, zygote
Gene ontology · 17
APIP → apoptotic process, cellular amino acid biosynthetic process, cytoplasm, cytosol, identical protein binding, L-methionine salvage from methylthioadenosine, L-methionine salvage from S-adenosylmethionine, lyase activity, metal ion binding, methionine biosynthetic process, methylthioribulose 1-phosphate dehydratase activity, negative regulation of apoptotic process, protein binding, protein homotetramerization, pyroptosis, regulation of ERK1 and ERK2 cascade, zinc ion binding
Band · 2
APIP → 11p13, 2|2 E2
Chr. · 2
APIP → Chromosome 11 (human), Chromosome 2 (mouse)
End · 2
APIP → 102,922,989 bp, 34,916,379 bp
related to External links · 2
APIP → Human APIP, UCSC Genome Browser
4.2.1.109 · 1
APIP → ↗
Aliases · 1
APIP → APIP, APIP2, CGI29, MMRP19, hCGI-29, APAF1 interacting protein
Available structures · 1
APIP → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4M6R

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp human gene chr band chromosome 11 location protein activity methionine mouse enzyme methylthioribulose 1-phosphate dehydratase salvage external search 916

APIP relationships Subject–Predicate–Object triples

TTTA extracted 83 structured relationships around APIP. Examples in this analysis include APIP → 4.2.1.109 → ↗ and APIP → Aliases → APIP, APIP2, CGI29, MMRP19, hCGI-29, APAF1 interacting protein. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
APIP4.2.1.1091.00infobox
APIPAliasesAPIP, APIP2, CGI29, MMRP19, hCGI-29, APAF1 interacting protein1.00infobox
APIPAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4M6R1.00infobox
APIPBand11p131.00infobox
APIPBand2|2 E21.00infobox
APIPBgeeC1 segment1.00infobox
APIPBgeemuscle of thigh1.00infobox
APIPBgeeright adrenal gland1.00infobox
APIPBgeecorpus callosum1.00infobox
APIPBgeeright adrenal cortex1.00infobox
APIPBgeemonocyte1.00infobox
APIPBgeeskeletal muscle tissue1.00infobox
APIPBgeeleft adrenal gland1.00infobox
APIPBgeeleft adrenal cortex1.00infobox
APIPBgeegastrocnemius muscle1.00infobox
APIPBgeeright ventricle1.00infobox
APIPBgeeinterventricular septum1.00infobox
APIPBgeezygote1.00infobox
APIPBgeecardiac muscle tissue of left ventricle1.00infobox
APIPBgeesecondary oocyte1.00infobox
APIPBgeeright kidney1.00infobox
APIPBgeedigastric muscle1.00infobox
APIPBgeetemporal muscle1.00infobox
APIPBgeebrown adipose tissue1.00infobox
APIPBioGPSMore reference expression data1.00infobox
APIPChr.Chromosome 11 (human)1.00infobox
APIPChr.Chromosome 2 (mouse)1.00infobox
APIPDatabasesNCBI: entry; OMA: entry1.00infobox
APIPEnd34,916,379 bp1.00infobox
APIPEnd102,922,989 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around APIP bring nearby vocabulary together. In this analysis, examples include Gene, Protein and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • APIP
    • Gene
    • Protein
    • Location
    • Human
    • Apaf1
    • Search
    • Ucsc
    • Activity
    • Chromosome
    • Bp
    • Chr
    • Associated
  • apip
    • Gene
    • Protein
    • Location
    • Human
    • Apaf1
    • Search
    • Ucsc
    • Activity
    • Chromosome
    • Bp
    • Chr
    • Associated
  • gene
    • Location
    • Human
    • Protein
    • Chromosome
    • Bp
    • Chr
    • Apaf1
    • End
    • Mouse
    • Search
    • Ucsc
    • Activity
  • methylthioribulose 1-phosphate dehydratase
    • Dehydratase
    • Methionine
    • Methylthioribulose
    • Salvage
    • Activity
    • Involved
    • Pathway
    • Apaf1
    • End
    • Enzyme
    • Mouse
    • Search
  • apaf1
    • Search
    • Protein
    • Chromosome
    • External
    • Interactions
    • Location
    • References
    • Apip
    • Bp
    • Chr
    • Gene
    • Human
  • methionine
    • Methylthioribulose
    • Salvage
    • Pathway
    • Apaf1
    • End
    • Mouse
    • Search
    • Ucsc
    • Protein
    • Band
    • Chromosome
    • Location
  • interactions
    • External
    • References
    • Apaf1
    • Search
    • Protein
    • Chromosome
    • Location
    • Bp
    • Chr
    • Human
  • protein
    • Search
    • Location
    • References
    • End
    • Mouse
    • Salvage
    • Ucsc
    • Band

Connections between topic areas Semantic bridges

For APIP, one of the stronger structural bridges in this analysis connects APIP with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
APIPOverview · splits 4 ⟂ 6
APIPInteractions · splits 7 ⟂ 3

Map overview Semantic statistics

APIP

Nodes10
Edges9
Triples83
Avg. degree1.8
Density0.2
Components1

Source & methodology

TTTA analyzes the structure around APIP to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — APIP · EN edition · Analysis: TopicsToTalkAbout

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