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APBA2: Function, Structure & Interactions

Amyloid beta A4 precursor protein-binding family A member 2 is a protein that in humans is encoded by the APBA2 gene.

Language: English [EN]
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APBA2 topic overview

The analysis highlights Function, Structure and Interactions as prominent areas in the source structure around APBA2.

Related topics
14
Source areas
4
Connected nodes
18
Extracted relationships
73
Related term clusters
10
Bridge connections
18

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 6 topics
Interactions · 3 topics
Structure · 3 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
APBA2, D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11-BETA, X11L, amyloid beta precursor protein binding family A member 2
Band
15q13.1 · 7 C|7 34.65 cM
Bgee
superior frontal gyrus · right hemisphere of cerebellum · primary visual cortex · prefrontal cortex · right frontal lobe
BioGPS
More reference expression data
Chr.
Chromosome 15 (human) · Chromosome 7 (mouse)
Databases
NCBI: entry; OMA: entry

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Interactions

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How APBA2 connects Entity context

The extracted context around APBA2 shows recurring relationship patterns in the source. For example, APBA2 → anterior cingulate cortex, Brodmann area 9, C1 segment, CA3 field, cerebellar cortex, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, ganglionic eminence, hippocampus proper, perirhinal cortex, prefrontal cortex, primary motor cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, superior frontal gyrus Another extracted example is APBA2 → amyloid-beta binding, chemical synaptic transmission, cytoplasm, dendritic spine, identical protein binding, in utero embryonic development, locomotory behavior, multicellular organism growth, nervous system development, plasma membrane, protein binding, protein transport, regulation of gene expression, regulation of synaptic vesicle exocytosis, Schaffer collateral - CA1 synapse, synapse, synaptic vesicle. Use these groups to spot repeated connection types before inspecting the individual relationships.

APBA2

Top relations

Bgee · 17
APBA2 → anterior cingulate cortex, Brodmann area 9, C1 segment, CA3 field, cerebellar cortex, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, ganglionic eminence, hippocampus proper, perirhinal cortex, prefrontal cortex, primary motor cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, superior frontal gyrus
Gene ontology · 17
APBA2 → amyloid-beta binding, chemical synaptic transmission, cytoplasm, dendritic spine, identical protein binding, in utero embryonic development, locomotory behavior, multicellular organism growth, nervous system development, plasma membrane, protein binding, protein transport, regulation of gene expression, regulation of synaptic vesicle exocytosis, Schaffer collateral - CA1 synapse, synapse, synaptic vesicle
RNA expression pattern · 17
APBA2 → anterior cingulate cortex, Brodmann area 9, C1 segment, CA3 field, cerebellar cortex, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, ganglionic eminence, hippocampus proper, perirhinal cortex, prefrontal cortex, primary motor cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, superior frontal gyrus
Band · 2
APBA2 → 15q13.1, 7 C|7 34.65 cM
Chr. · 2
APBA2 → Chromosome 15 (human), Chromosome 7 (mouse)
End · 2
APBA2 → 29,118,315 bp, 64,753,878 bp
related to Interactions · 2
APBA2 → CLSTN1, RELA
Aliases · 1
APBA2 → APBA2, D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11-BETA, X11L, amyloid beta precursor protein binding family A member 2
BioGPS · 1
APBA2 → More reference expression data
Databases · 1
APBA2 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein gene bp human chr band chromosome 15 amyloid precursor location beta family member mouse function external encoded binding 118

APBA2 relationships Subject–Predicate–Object triples

TTTA extracted 73 structured relationships around APBA2. Examples in this analysis include APBA2 → Aliases → APBA2, D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11-BETA, X11L, amyloid beta precursor protein binding family A member 2 and APBA2 → Band → 15q13.1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
APBA2AliasesAPBA2, D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11-BETA, X11L, amyloid beta precursor protein binding family A member 21.00infobox
APBA2Band15q13.11.00infobox
APBA2Band7 C|7 34.65 cM1.00infobox
APBA2Bgeesuperior frontal gyrus1.00infobox
APBA2Bgeeright hemisphere of cerebellum1.00infobox
APBA2Bgeeprimary visual cortex1.00infobox
APBA2Bgeeprefrontal cortex1.00infobox
APBA2Bgeeright frontal lobe1.00infobox
APBA2BgeeBrodmann area 91.00infobox
APBA2Bgeeanterior cingulate cortex1.00infobox
APBA2Bgeehippocampus proper1.00infobox
APBA2Bgeeganglionic eminence1.00infobox
APBA2BgeeC1 segment1.00infobox
APBA2Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
APBA2Bgeeperirhinal cortex1.00infobox
APBA2BgeeCA3 field1.00infobox
APBA2Bgeeentorhinal cortex1.00infobox
APBA2Bgeecerebellar cortex1.00infobox
APBA2Bgeeprimary motor cortex1.00infobox
APBA2Bgeecingulate gyrus1.00infobox
APBA2BioGPSMore reference expression data1.00infobox
APBA2Chr.Chromosome 15 (human)1.00infobox
APBA2Chr.Chromosome 7 (mouse)1.00infobox
APBA2DatabasesNCBI: entry; OMA: entry1.00infobox
APBA2End29,118,315 bp1.00infobox
APBA2End64,753,878 bp1.00infobox
APBA2EnsemblENSG00000034053 ENSG000002764951.00infobox
APBA2Entrez3211.00infobox
APBA2External IDsOMIM: 602712; MGI: 1261791; GeneCards: APBA21.00infobox
APBA2Gene location (Human)Gene location (Human)Chr.Chromosome 15 (human)Band15q13.1Start28,884,483 bpEnd29,118,315 bp1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around APBA2 bring nearby vocabulary together. In this analysis, examples include Gene, Location and Precursor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • APBA2
    • Gene
    • Location
    • Precursor
    • Protein
    • Human
    • Binding
    • Function
    • Ucsc
    • Beta
    • Family
    • Member
    • Chromosome
  • apba2
    • Gene
    • Location
    • Precursor
    • Protein
    • Human
    • Binding
    • Function
    • Ucsc
    • Beta
    • Family
    • Member
    • Chromosome
  • amyloid precursor protein
    • Precursor
    • Protein
    • Apba2
    • Beta
    • Family
    • Member
    • Binding
    • Cell
    • Exocytosis
    • Function
    • Neuronal
    • Synaptic
  • protein
    • Binding
    • Cell
    • Exocytosis
    • Function
    • Neuronal
    • Synaptic
    • Vesicle
    • Chromosome
    • Location
    • Bp
    • Chr
    • Human
  • gene
    • Location
    • Human
    • Member
    • Protein
    • Chromosome
    • Bp
    • Chr
    • Binding
    • End
    • Function
    • Mouse
    • Ucsc
  • a beta peptide
    • Family
    • Member
    • Precursor
    • Apba2
    • External
    • Humans
    • Protein-binding
    • Alzheimer's
    • App
    • Binding
    • Disease
    • Encoded
  • synaptic vesicle
    • Cell
    • Exocytosis
    • Synaptic
    • Vesicle
    • Binding
    • End
    • Function
    • Mouse
    • Neuronal
    • Ucsc
    • Protein
    • Band
  • function
    • Binding
    • Chromosome
    • Location
    • Bp
    • Chr
    • Human
    • Cell
    • End
    • Exocytosis
    • Mouse
    • Synaptic
    • Ucsc

Connections between topic areas Semantic bridges

For APBA2, one of the stronger structural bridges in this analysis connects APBA2 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
APBA2 — Function · splits 12 ⟂ 7
APBA2 — Structure · splits 15 ⟂ 4
APBA2 — Interactions · splits 15 ⟂ 4
APBA2 — Overview · splits 16 ⟂ 3

Map overview Semantic statistics

APBA2

Nodes19
Edges18
Triples73
Avg. degree1.89
Density0.105263
Components1

Source & methodology

TTTA analyzes the structure around APBA2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Structure & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — APBA2 · EN edition · Analysis: TopicsToTalkAbout

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