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Amoxicillin/clavulanic acid: History, Applications & Research

Amoxicillin/clavulanic acid, also known as co-amoxiclav or amox-clav, sold under the brand names Augmentin, and Ranclav among others, is an antibiotic medication used for the treatment of a number of bacterial infections. It is a combination consisting of amoxicillin, a β-lactam antibiotic, and potassium clavulanate, a β-lactamase inhibitor. It is…

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Amoxicillin/clavulanic acid topic overview

The analysis highlights History, Applications and Research as prominent areas in the source structure around Amoxicillin/clavulanic acid.

Related topics
109
Source areas
6
Connected nodes
115
Extracted relationships
86
Concept neighborhoods
33
Bridge connections
115

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 48 topics
Medical uses · 37 topics
Pharmacology · 13 topics
History · 4 topics
Preparations · 4 topics
Miscellaneous research · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
Amoxicillin
Penicillin antibiotic
ATC code
J01CR02 (WHO) QJ01CR02 (WHO)
CAS Number
74469-00-4 · 74428-36-7
ChEMBL
ChEMBL1697738

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

History

Preparations

Medical uses

Pharmacology

Miscellaneous research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Amoxicillin/clavulanic acid connects Entity context

The extracted context around Amoxicillin/clavulanic acid shows recurring relationship patterns in the source. For example, Amoxicillin/clavulanic acid → Amoxicillin/clavulanic, AmpC, As, CRE, Enterobacteriaceae, Enterococci, Enterococcus, ESBL, ESBL-producing Gram-negative, Escherichia, Gram-negative, In, It, Klebsiella, Morganella, Proteus, Providencia, Pseudomonas, Staphylococcus, The Another extracted example is Amoxicillin/clavulanic acid → As, Clostridioides, Committee, In, It, Medicines, Possible, Rarely, Safety, The, These, United Kingdom. Use these groups to spot repeated connection types before inspecting the individual relationships.

Amoxicillin/clavulanic acid

Top relations

related to Urinary tract infections · 22
Amoxicillin/clavulanic acid → Amoxicillin/clavulanic, AmpC, As, CRE, Enterobacteriaceae, Enterococci, Enterococcus, ESBL, ESBL-producing Gram-negative, Escherichia, Gram-negative, In, It, Klebsiella, Morganella, Proteus, Providencia, Pseudomonas, Staphylococcus, The
has effect · 12
Amoxicillin/clavulanic acid → As, Clostridioides, Committee, In, It, Medicines, Possible, Rarely, Safety, The, These, United Kingdom
related to history · 10
Amoxicillin/clavulanic acid → Amoxicillin/clavulanic, Augmentin, BAN, Beecham, British, British Approved Name, GlaxoSmithKline, INN, International Nonproprietary Name, It
related to Preparations · 7
Amoxicillin/clavulanic acid → As, Augmentin, Branded, Intravenous, The, UK, US
related to Veterinary use · 5
Amoxicillin/clavulanic acid → Approved Animal Drug Products, April, As, FDA, Green Book
Legal status · 4
Amoxicillin/clavulanic acid → AU: S4 (Prescription only), CA: ℞-only, UK: POM (Prescription only), US: ℞-only
CAS Number · 2
Amoxicillin/clavulanic acid → 74428-36-7, 74469-00-4
3D model (JSmol) · 1
Amoxicillin/clavulanic acid → Interactive image
AHFS/Drugs.com · 1
Amoxicillin/clavulanic acid → Monograph
Amoxicillin · 1
Amoxicillin/clavulanic acid → Penicillin antibiotic

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

amoxicillin clavulanic acid infections treatment antibiotic used bacteria use also utis medication urinary tract effects co-amoxiclav tuberculosis susceptible due combination

Amoxicillin/clavulanic acid relationships Subject–Predicate–Object triples

TTTA extracted 86 structured relationships around Amoxicillin/clavulanic acid. Examples in this analysis include Amoxicillin/clavulanic acid → 3D model (JSmol) → Interactive image and Amoxicillin/clavulanic acid → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Amoxicillin/clavulanic acid3D model (JSmol)Interactive image1.00infobox
Amoxicillin/clavulanic acidAHFS/Drugs.comMonograph1.00infobox
Amoxicillin/clavulanic acidAmoxicillinPenicillin antibiotic1.00infobox
Amoxicillin/clavulanic acidATC codeJ01CR02 (WHO) QJ01CR02 (WHO)1.00infobox
Amoxicillin/clavulanic acidCAS Number74469-00-41.00infobox
Amoxicillin/clavulanic acidCAS Number74428-36-71.00infobox
Amoxicillin/clavulanic acidChEMBLChEMBL16977381.00infobox
Amoxicillin/clavulanic acidChemSpider49406081.00infobox
Amoxicillin/clavulanic acidClavulanic acidBeta-lactamase inhibitor1.00infobox
Amoxicillin/clavulanic acidCompTox Dashboard (EPA)DTXSID402254771.00infobox
Amoxicillin/clavulanic acidFormulaC24H27KN4O10S1.00infobox
Amoxicillin/clavulanic acidKEGGD064851.00infobox
Amoxicillin/clavulanic acidLegal statusAU: S4 (Prescription only)1.00infobox
Amoxicillin/clavulanic acidLegal statusCA: ℞-only1.00infobox
Amoxicillin/clavulanic acidLegal statusUK: POM (Prescription only)1.00infobox
Amoxicillin/clavulanic acidLegal statusUS: ℞-only1.00infobox
Amoxicillin/clavulanic acidLicense dataUS DailyMed: Amoxicillin clavulanate1.00infobox
Amoxicillin/clavulanic acidMedlinePlusa6850241.00infobox
Amoxicillin/clavulanic acidMolar mass602.66 g·mol−11.00infobox
Amoxicillin/clavulanic acidOther namesCo-amoxiclav; Amox-clav1.00infobox
Amoxicillin/clavulanic acidPregnancy categoryAU: B11.00infobox
Amoxicillin/clavulanic acidPubChem CID64359241.00infobox
Amoxicillin/clavulanic acidRoutes of administrationBy mouth, intravenous1.00infobox
Amoxicillin/clavulanic acidTrade namesAugmentin, Clavulin, Amoclan, others1.00infobox
Amoxicillin/clavulanic acidis aInternational Nonproprietary Name0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Amoxicillin/clavulanic acid bring nearby vocabulary together. In this analysis, examples include Acid, Amoxicillin and Clavulanic. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Amoxicillin/clavulanic acid
    • Acid
    • Amoxicillin
    • Clavulanic
    • Antibiotic
    • Bacteria
    • Infections
    • Used
    • Treatment
    • Augmentin
    • Bacterial
    • Beta-lactamase
    • Clavulanate
  • amoxicillin/clavulanic acid
    • Clavulanic
    • Acid
    • Amoxicillin
    • Treatment
    • Bacteria
    • Infections
    • Used
    • Augmentin
    • Bacterial
    • Beta-lactamase
    • Due
    • Antibiotic
  • antibiotic
    • Inhibitor
    • Augmentin
    • Clavulanate
    • Co-amoxiclav
    • Penicillin
    • Combination
    • Β-lactamase
    • Infections
    • Clavulanic
    • Bacterial
    • Beta-lactamase
    • Medical
  • bacterial infections
    • Tract
    • Urinary
    • Used
    • Cellulitis
    • Beta-lactamase
    • Due
    • Infections
    • Pregnancy
    • Susceptible
    • Utis
    • Needed
    • Tuberculosis
  • amoxicillin
    • Acid
    • Clavulanic
    • Antibiotic
    • Bacteria
    • Infections
    • Used
    • Treatment
    • Augmentin
    • Bacterial
    • Beta-lactamase
    • Clavulanate
    • Co-amoxiclav
  • β-lactam antibiotic
    • Inhibitor
    • Augmentin
    • Clavulanate
    • Co-amoxiclav
    • Penicillin
    • Combination
    • Β-lactamase
    • Infections
    • Clavulanic
    • Bacterial
    • Beta-lactamase
    • Medical
  • clavulanic acid
    • Clavulanic
    • Amoxicillin
    • Treatment
    • Bacteria
    • Infections
    • Used
    • Augmentin
    • Bacterial
    • Beta-lactamase
    • Due
    • Needed
    • Tract
  • antibiotic resistance
    • Inhibitor
    • Augmentin
    • Clavulanate
    • Co-amoxiclav
    • Penicillin
    • Combination
    • Β-lactamase
    • Infections
    • Clavulanic
    • Bacterial
    • Beta-lactamase
    • Medical

Connections between topic areas Semantic bridges

For Amoxicillin/clavulanic acid, one of the stronger structural bridges in this analysis connects Amoxicillin/clavulanic acid with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Amoxicillin/clavulanic acidOverview · splits 67 ⟂ 49
Amoxicillin/clavulanic acidMedical uses · splits 78 ⟂ 38
Amoxicillin/clavulanic acidPharmacology · splits 102 ⟂ 14
Amoxicillin/clavulanic acidHistory · splits 111 ⟂ 5
Amoxicillin/clavulanic acidPreparations · splits 111 ⟂ 5
Amoxicillin/clavulanic acidMiscellaneous research · splits 112 ⟂ 4

Map overview Semantic statistics

Amoxicillin/clavulanic acid

Nodes116
Edges115
Triples86
Avg. degree1.98
Density0.017241
Components1

Source & methodology

TTTA analyzes the structure around Amoxicillin/clavulanic acid to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Applications & Research, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Amoxicillin/clavulanic acid · EN edition · Analysis: TopicsToTalkAbout

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