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Afamelanotide, sold under the brand name Scenesse, is a medication used to prevent phototoxicity and to reduce pain from light exposure for people with erythropoietic protoporphyria, a rare form of genetic sun sensitivity. Afamelanotide is a melanocortin 1 receptor (MC1 receptor) agonist and a synthetic peptide and analogue of α-melanocyte stimulating…
The analysis highlights History, Adverse effects and Pharmacology as prominent areas in the source structure around Afamelanotide.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Afamelanotide shows recurring relationship patterns in the source. For example, Afamelanotide → Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2, D-Phe7, It, MSH, NDP-MSH, NDP-α-MSH, Nle4 Another extracted example is Afamelanotide → Arizona, By, II, In, Later, MSH, University. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
trials effects erythropoietic protoporphyria skin drug us name light exposure phototoxicity adverse α-msh half-life peptide reactions clinical clinuvel sold medication
TTTA extracted 57 structured relationships around Afamelanotide. Examples in this analysis include Afamelanotide → 3D model (JSmol) → Interactive image and Afamelanotide → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Afamelanotide | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| Afamelanotide | AHFS/Drugs.com | Monograph | 1.00 | infobox |
| Afamelanotide | ATC code | D02BB02 (WHO) | 1.00 | infobox |
| Afamelanotide | CAS Number | 75921-69-6 N | 1.00 | infobox |
| Afamelanotide | ChEBI | CHEBI:136034 | 1.00 | infobox |
| Afamelanotide | ChEMBL | ChEMBL441738 Y | 1.00 | infobox |
| Afamelanotide | ChemSpider | 17310725 Y | 1.00 | infobox |
| Afamelanotide | CompTox Dashboard (EPA) | DTXSID40226843 | 1.00 | infobox |
| Afamelanotide | DrugBank | DB04931 | 1.00 | infobox |
| Afamelanotide | Elimination half-life | 30 minutes | 1.00 | infobox |
| Afamelanotide | Formula | C78H111N21O19 | 1.00 | infobox |
| Afamelanotide | IUPHAR/BPS | 1324 | 1.00 | infobox |
| Afamelanotide | KEGG | D10511 N | 1.00 | infobox |
| Afamelanotide | KEGG | as salt: D11334 N | 1.00 | infobox |
| Afamelanotide | Legal status | AU: S4 (Prescription only) | 1.00 | infobox |
| Afamelanotide | Legal status | UK: POM (Prescription only) | 1.00 | infobox |
| Afamelanotide | Legal status | US: ℞-only | 1.00 | infobox |
| Afamelanotide | Legal status | EU: Rx-only | 1.00 | infobox |
| Afamelanotide | License data | US DailyMed: Afamelanotide | 1.00 | infobox |
| Afamelanotide | Molar mass | 1646.874 g·mol−1 | 1.00 | infobox |
| Afamelanotide | Other names | [Nle4,D-Phe7]α-MSH; NDP-α-MSH; NDP-MSH; Melanotan; Melanotan-1; Melanotan I; EPT1647; CUV1647; | 1.00 | infobox |
| Afamelanotide | Pregnancy category | AU: B1 | 1.00 | infobox |
| Afamelanotide | Pronunciation | /ˌæfəmɛˈlænoʊtaɪd/ ⓘ | 1.00 | infobox |
| Afamelanotide | PubChem CID | 16154396 | 1.00 | infobox |
| Afamelanotide | Routes of administration | Subcutaneous | 1.00 | infobox |
| Afamelanotide | Trade names | Scenesse | 1.00 | infobox |
| Afamelanotide | UNII | QW68W3J66U | 1.00 | infobox |
| Afamelanotide | is a | melanocortin 1 receptor | 0.90 | text |
| Afamelanotide | is a | international nonproprietary name | 0.90 | text |
The concept neighborhoods around Afamelanotide bring nearby vocabulary together. In this analysis, examples include Exposure, Erythropoietic and Protoporphyria. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Afamelanotide, one of the stronger structural bridges in this analysis connects Afamelanotide with Adverse effects. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Afamelanotide to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Adverse effects & Pharmacology, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Afamelanotide · EN edition · Analysis: TopicsToTalkAbout