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Afamelanotide

Afamelanotide, sold under the brand name Scenesse, is a medication used to prevent phototoxicity and to reduce pain from light exposure for people with erythropoietic protoporphyria, a rare form of genetic sun sensitivity. Afamelanotide is a melanocortin 1 receptor (MC1 receptor) agonist and a synthetic peptide and analogue of α-melanocyte stimulating…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
D02BB02 (WHO)
CAS Number
75921-69-6 N
ChEBI
CHEBI:136034
ChEMBL
ChEMBL441738 Y

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Pharmacology

Chemistry

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Afamelanotide

Nodes77
Edges76
Triples57
Avg. degree1.97
Density0.025974
Components1

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Afamelanotide

Top relations

related to Chemistry · 7
Afamelanotide → Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2, D-Phe7, It, MSH, NDP-MSH, NDP-α-MSH, Nle4
related to history · 7
Afamelanotide → Arizona, By, II, In, Later, MSH, University
related to Pharmacology · 7
Afamelanotide → After, By, It, Its, MC1, MSH, This
Legal status · 4
Afamelanotide → AU: S4 (Prescription only), EU: Rx-only, UK: POM (Prescription only), US: ℞-only
has effect · 3
Afamelanotide → Other, The, Uncommon
related to Medical uses · 3
Afamelanotide → European Union, In, United States
KEGG · 2
Afamelanotide → as salt: D11334 N, D10511 N
is a · 2
Afamelanotide → international nonproprietary name, melanocortin 1 receptor
3D model (JSmol) · 1
Afamelanotide → Interactive image
AHFS/Drugs.com · 1
Afamelanotide → Monograph

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Important terminology

trials effects erythropoietic protoporphyria skin drug us name light exposure phototoxicity adverse α-msh half-life peptide reactions clinical clinuvel sold medication

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Afamelanotide3D model (JSmol)Interactive image1.00infobox
AfamelanotideAHFS/Drugs.comMonograph1.00infobox
AfamelanotideATC codeD02BB02 (WHO)1.00infobox
AfamelanotideCAS Number75921-69-6 N1.00infobox
AfamelanotideChEBICHEBI:1360341.00infobox
AfamelanotideChEMBLChEMBL441738 Y1.00infobox
AfamelanotideChemSpider17310725 Y1.00infobox
AfamelanotideCompTox Dashboard (EPA)DTXSID402268431.00infobox
AfamelanotideDrugBankDB049311.00infobox
AfamelanotideElimination half-life30 minutes1.00infobox
AfamelanotideFormulaC78H111N21O191.00infobox
AfamelanotideIUPHAR/BPS13241.00infobox
AfamelanotideKEGGD10511 N1.00infobox
AfamelanotideKEGGas salt: D11334 N1.00infobox
AfamelanotideLegal statusAU: S4 (Prescription only)1.00infobox
AfamelanotideLegal statusUK: POM (Prescription only)1.00infobox
AfamelanotideLegal statusUS: ℞-only1.00infobox
AfamelanotideLegal statusEU: Rx-only1.00infobox
AfamelanotideLicense dataUS DailyMed: Afamelanotide1.00infobox
AfamelanotideMolar mass1646.874 g·mol−11.00infobox
AfamelanotideOther names[Nle4,D-Phe7]α-MSH; NDP-α-MSH; NDP-MSH; Melanotan; Melanotan-1; Melanotan I; EPT1647; CUV1647;1.00infobox
AfamelanotidePregnancy categoryAU: B11.00infobox
AfamelanotidePronunciation/ˌæfəmɛˈlænoʊtaɪd/ ⓘ1.00infobox
AfamelanotidePubChem CID161543961.00infobox
AfamelanotideRoutes of administrationSubcutaneous1.00infobox
AfamelanotideTrade namesScenesse1.00infobox
AfamelanotideUNIIQW68W3J66U1.00infobox
Afamelanotideis amelanocortin 1 receptor0.90text
Afamelanotideis ainternational nonproprietary name0.90text

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