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ADCY2: Regions & Standards

Adenylyl cyclase type 2 is an enzyme typically expressed in the brain of humans, that is encoded by the ADCY2 gene. It belongs to the adenylyl cyclase class-3 or guanylyl cyclase family because it contains two guanylate cyclase domains. ADCY2 is one of ten different mammalian isoforms of adenylyl cyclases. ADCY2 can be found on chromosome 5 and the…

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ADCY2 topic overview

The analysis highlights Regions and Standards as prominent areas in the source structure around ADCY2.

Related topics
19
Source areas
4
Connected nodes
23
Extracted relationships
140
Concept neighborhoods
9
Bridge connections
23

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical significance · 10 topics
Function · 6 topics
Overview · 2 topics
Structure · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

4.6.1.1
Aliases
ADCY2, AC2, HBAC2, adenylate cyclase 2 (brain), adenylate cyclase 2
Band
5p15.31 · 13 B3|13 35.55 cM
Bgee
middle temporal gyrus · Brodmann area 23 · dorsal motor nucleus of vagus nerve · Skeletal muscle tissue of rectus abdominis · entorhinal cortex
BioGPS
More reference expression data
Chr.
Chromosome 5 (human) · Chromosome 13 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How ADCY2 connects Entity context

The extracted context around ADCY2 shows recurring relationship patterns in the source. For example, ADCY2 → activation of adenylate cyclase activity, activation of protein kinase A activity, adenylate cyclase activity, adenylate cyclase binding, adenylate cyclase-activating G protein-coupled receptor signaling pathway, adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, adenylate cyclase-modulating G protein-coupled receptor signaling pathway, ATP binding, cAMP biosynthetic process, cAMP-mediated signaling, cellular response to forskolin, cellular response to glucagon stimulus, cGMP biosynthetic process, cyclic nucleotide biosynthetic process, cytoplasm, dendrite, G protein-coupled receptor signaling pathway, guanylate cyclase activity, guanylate cyclase complex, soluble, integral component of membrane Another extracted example is ADCY2 → biceps brachii, Brodmann area 23, CA3 field, cingulate gyrus, deltoid muscle, digastric muscle, dorsal motor nucleus of vagus nerve, entorhinal cortex, extraocular muscle, middle temporal gyrus, muscle of thigh, postcentral gyrus, primary motor cortex, primary visual cortex, Region I of hippocampus proper, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, sternocleidomastoid muscle, superior frontal gyrus, temporal muscle. Use these groups to spot repeated connection types before inspecting the individual relationships.

ADCY2

Top relations

Gene ontology · 35
ADCY2 → activation of adenylate cyclase activity, activation of protein kinase A activity, adenylate cyclase activity, adenylate cyclase binding, adenylate cyclase-activating G protein-coupled receptor signaling pathway, adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, adenylate cyclase-modulating G protein-coupled receptor signaling pathway, ATP binding, cAMP biosynthetic process, cAMP-mediated signaling, cellular response to forskolin, cellular response to glucagon stimulus, cGMP biosynthetic process, cyclic nucleotide biosynthetic process, cytoplasm, dendrite, G protein-coupled receptor signaling pathway, guanylate cyclase activity, guanylate cyclase complex, soluble, integral component of membrane
Bgee · 20
ADCY2 → biceps brachii, Brodmann area 23, CA3 field, cingulate gyrus, deltoid muscle, digastric muscle, dorsal motor nucleus of vagus nerve, entorhinal cortex, extraocular muscle, middle temporal gyrus, muscle of thigh, postcentral gyrus, primary motor cortex, primary visual cortex, Region I of hippocampus proper, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, sternocleidomastoid muscle, superior frontal gyrus, temporal muscle
RNA expression pattern · 20
ADCY2 → biceps brachii, Brodmann area 23, CA3 field, cingulate gyrus, deltoid muscle, digastric muscle, dorsal motor nucleus of vagus nerve, entorhinal cortex, extraocular muscle, middle temporal gyrus, muscle of thigh, postcentral gyrus, primary motor cortex, primary visual cortex, Region I of hippocampus proper, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, sternocleidomastoid muscle, superior frontal gyrus, temporal muscle
related to Function · 16
ADCY2 → A-kinase-anchoring, AKAP, AKAP-anchored, ATP, Ca2, G-proteins, Gq-coupled, In, Once, PDE4, PKC, Raf, Recently, The, Therefore, This
related to Structure · 13
ADCY2 → ADCY1, C1, C2, C2a, HBA C1, In, N-terminus, Outside, Structurally, The, The C1a, Then, This
related to Clinical significance · 12
ADCY2 → Anthrax, COPD, During, IP3, NCALD, Perturbations, PKA, Polymorphisms, SCN7A, SPAG16, This, WDR60
Band · 2
ADCY2 → 13 B3|13 35.55 cM, 5p15.31
Chr. · 2
ADCY2 → Chromosome 13 (mouse), Chromosome 5 (human)
End · 2
ADCY2 → 69,147,660 bp, 7,830,081 bp
related to External links · 2
ADCY2 → Human ADCY2, UCSC Genome Browser

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

human adenylyl cyclase gene bp chromosome protein chr band enzyme camp kinase brain location function cyclases expressed structure pathway domain

ADCY2 relationships Subject–Predicate–Object triples

TTTA extracted 140 structured relationships around ADCY2. Examples in this analysis include ADCY2 → 4.6.1.1 → ↗ and ADCY2 → Aliases → ADCY2, AC2, HBAC2, adenylate cyclase 2 (brain), adenylate cyclase 2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
ADCY24.6.1.11.00infobox
ADCY2AliasesADCY2, AC2, HBAC2, adenylate cyclase 2 (brain), adenylate cyclase 21.00infobox
ADCY2Band5p15.311.00infobox
ADCY2Band13 B3|13 35.55 cM1.00infobox
ADCY2Bgeemiddle temporal gyrus1.00infobox
ADCY2BgeeBrodmann area 231.00infobox
ADCY2Bgeedorsal motor nucleus of vagus nerve1.00infobox
ADCY2BgeeSkeletal muscle tissue of rectus abdominis1.00infobox
ADCY2Bgeeentorhinal cortex1.00infobox
ADCY2Bgeepostcentral gyrus1.00infobox
ADCY2Bgeemuscle of thigh1.00infobox
ADCY2Bgeebiceps brachii1.00infobox
ADCY2Bgeedeltoid muscle1.00infobox
ADCY2BgeeSkeletal muscle tissue of biceps brachii1.00infobox
ADCY2Bgeeprimary motor cortex1.00infobox
ADCY2BgeeCA3 field1.00infobox
ADCY2Bgeecingulate gyrus1.00infobox
ADCY2Bgeedigastric muscle1.00infobox
ADCY2BgeeRegion I of hippocampus proper1.00infobox
ADCY2Bgeeprimary visual cortex1.00infobox
ADCY2Bgeetemporal muscle1.00infobox
ADCY2Bgeesuperior frontal gyrus1.00infobox
ADCY2Bgeeextraocular muscle1.00infobox
ADCY2Bgeesternocleidomastoid muscle1.00infobox
ADCY2BioGPSMore reference expression data1.00infobox
ADCY2Chr.Chromosome 5 (human)1.00infobox
ADCY2Chr.Chromosome 13 (mouse)1.00infobox
ADCY2DatabasesNCBI: entry; OMA: entry1.00infobox
ADCY2End7,830,081 bp1.00infobox
ADCY2End69,147,660 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around ADCY2 bring nearby vocabulary together. In this analysis, examples include Gene, Protein and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • ADCY2
    • Gene
    • Protein
    • Human
    • Activation
    • Pathway
    • Function
    • Location
    • Camp
    • Chromosome
    • Kinase
    • Cyclase
    • Adenylate
  • adcy2
    • Gene
    • Protein
    • Human
    • Activation
    • Pathway
    • Function
    • Location
    • Camp
    • Chromosome
    • Kinase
    • Cyclase
    • Adenylate
  • gene
    • Location
    • Function
    • Human
    • Bp
    • Chr
    • Chromosome
    • Adenylate
    • Mouse
    • Activity
    • Pathway
    • Structure
    • Band
  • structure
    • Adenylate
    • Activity
    • Pathway
    • Brain
    • Function
    • Location
    • Cyclase
    • Human
    • Bp
    • Chr
    • Chromosome
    • External
  • adenylyl cyclases
    • Cyclase
    • Cyclases
    • Mammalian
    • Brain
    • Family
    • Type
    • Expressed
    • Different
    • C1
    • Cytoplasmic
    • Found
    • Structure
  • function
    • Adenylate
    • Activity
    • Pathway
    • Structure
    • Gene
    • Location
    • Bp
    • Chr
    • External
    • Guanylate
    • Human
    • Magnesium
  • enzyme
    • External
    • Adenylate
    • Gene
    • Subunit
    • Type
    • Activity
    • Expressed
    • Pathway
    • Structure
    • Function
    • Location
    • Bp
  • protein kinase c
    • Protein
    • Pathway
    • Segments
    • Magnesium
    • Mouse
    • Region
    • Type
    • Structure
    • Location
    • Subunit
    • C1
    • Cytoplasmic

Connections between topic areas Semantic bridges

For ADCY2, one of the stronger structural bridges in this analysis connects ADCY2 with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
ADCY2Clinical significance · splits 13 ⟂ 11
ADCY2Function · splits 17 ⟂ 7
ADCY2Overview · splits 21 ⟂ 3

Map overview Semantic statistics

ADCY2

Nodes24
Edges23
Triples140
Avg. degree1.92
Density0.083333
Components1

Source & methodology

TTTA analyzes the structure around ADCY2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions & Standards, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — ADCY2 · EN edition · Analysis: TopicsToTalkAbout

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