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SCN7A

Nax is a protein that in humans is encoded by the SCN7A (Sodium channel protein type 7) gene. It is a sodium channel alpha subunit expressed in the heart, the uterus and in glial cells of mice. It has low similarity to all nine other sodium channel alpha subunits (Nav1.1–1.9).

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Function

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Evolution

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Aliases
SCN7A, NaG, Nav2.1, Nav2.2, SCN6A, sodium voltage-gated channel alpha subunit 7
Band
2q24.3 · 2 C1.3|2 39.21 cM
Bgee
trigeminal ganglion · sural nerve · right lung · spinal ganglia · lower lobe of lung
BioGPS
More reference expression data
Chr.
Chromosome 2 (human) · Chromosome 2 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

Function

Evolution

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Map overview Semantic statistics

SCN7A

Nodes12
Edges11
Triples98
Avg. degree1.83
Density0.166667
Components1

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SCN7A

Top relations

Gene ontology · 21
SCN7A → axon, glial cell projection, integral component of membrane, ion channel activity, ion transmembrane transport, ion transport, membrane, membrane depolarization during action potential, muscle contraction, neuronal action potential, plasma membrane, regulation of ion transmembrane transport, response to bacterium, sodium channel activity, sodium ion homeostasis, sodium ion transmembrane transport, sodium ion transport, transmembrane transport, voltage-gated ion channel activity, voltage-gated sodium channel activity
Bgee · 18
SCN7A → aortic valve, arcuate nucleus, carotid body, left lung lobe, left ovary, lower lobe of lung, lumbar spinal ganglion, median eminence, muscle layer of sigmoid colon, right lung, right lung lobe, right ventricle, seminal vesicula, spinal ganglia, sural nerve, trigeminal ganglion, visceral pleura, white adipose tissue
RNA expression pattern · 18
SCN7A → aortic valve, arcuate nucleus, carotid body, left lung lobe, left ovary, lower lobe of lung, lumbar spinal ganglion, median eminence, muscle layer of sigmoid colon, right lung, right lung lobe, right ventricle, seminal vesicula, spinal ganglia, sural nerve, trigeminal ganglion, visceral pleura, white adipose tissue
related to External links · 9
SCN7A → Man, Medicine, Medicine Medical Subject Headings, MeSH, National Library, OMIM, Online Mendelian Inheritance, This, United States National Library
related to Putative ion channel · 6
SCN7A → EM, QTT, SCN7A-QTT, The, This, When
related to Sodium sensor · 4
SCN7A → Compared, In, Mouse Scn7a, VGNCs
Band · 2
SCN7A → 2 C1.3|2 39.21 cM, 2q24.3
Chr. · 2
SCN7A → Chromosome 2 (human), Chromosome 2 (mouse)
End · 2
SCN7A → 166,611,482 bp, 66,615,258 bp
related to Function · 2
SCN7A → Scientists, There

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Important terminology

sodium channel human bp gene chr band mouse ion nax chromosome alpha voltage-gated protein location function humans cells mice sensor

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
SCN7AAliasesSCN7A, NaG, Nav2.1, Nav2.2, SCN6A, sodium voltage-gated channel alpha subunit 71.00infobox
SCN7ABand2q24.31.00infobox
SCN7ABand2 C1.3|2 39.21 cM1.00infobox
SCN7ABgeetrigeminal ganglion1.00infobox
SCN7ABgeesural nerve1.00infobox
SCN7ABgeeright lung1.00infobox
SCN7ABgeespinal ganglia1.00infobox
SCN7ABgeelower lobe of lung1.00infobox
SCN7ABgeeseminal vesicula1.00infobox
SCN7ABgeeright ventricle1.00infobox
SCN7ABgeeleft ovary1.00infobox
SCN7ABgeevisceral pleura1.00infobox
SCN7ABgeemuscle layer of sigmoid colon1.00infobox
SCN7ABgeeleft lung lobe1.00infobox
SCN7ABgeecarotid body1.00infobox
SCN7ABgeemedian eminence1.00infobox
SCN7ABgeelumbar spinal ganglion1.00infobox
SCN7ABgeeright lung lobe1.00infobox
SCN7ABgeewhite adipose tissue1.00infobox
SCN7ABgeearcuate nucleus1.00infobox
SCN7ABgeeaortic valve1.00infobox
SCN7ABioGPSMore reference expression data1.00infobox
SCN7AChr.Chromosome 2 (human)1.00infobox
SCN7AChr.Chromosome 2 (mouse)1.00infobox
SCN7ADatabasesNCBI: entry; OMA: entry1.00infobox
SCN7AEnd166,611,482 bp1.00infobox
SCN7AEnd66,615,258 bp1.00infobox
SCN7AEnsemblENSG000001365461.00infobox
SCN7AEntrez63321.00infobox
SCN7AExternal IDsOMIM: 182392; MGI: 102965; GeneCards: SCN7A1.00infobox

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