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Acetolactate synthase: Standards, Inhibitors & Regulation

The acetolactate synthase (ALS) enzyme (also known as acetohydroxy acid or acetohydroxyacid synthase, abbr. AHAS) is a protein found in plants and micro-organisms. ALS catalyzes the first step in the synthesis of the branched-chain amino acids (valine, leucine, and isoleucine).

Language: English [EN]
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Acetolactate synthase topic overview

The analysis highlights Standards, Inhibitors and Regulation as prominent areas in the source structure around Acetolactate synthase.

Related topics
43
Source areas
7
Connected nodes
50
Extracted relationships
60
Concept neighborhoods
23
Bridge connections
50

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Inhibitors · 14 topics
Regulation · 11 topics
Structure · 5 topics
Overview · 4 topics
Catalytic activity · 3 topics
Function · 3 topics
Interactions · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Alt. names
pyruvate:pyruvate acetaldehydetransferase (decarboxylating)
BRENDA
enzyme data
CAS no.
9027-45-6
EC no.
2.2.1.6
ExPASy
NiceZyme view
Gene Ontology
AmiGO / QuickGO

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Catalytic activity

Regulation

Inhibitors

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Acetolactate synthase connects Entity context

The extracted context around Acetolactate synthase shows recurring relationship patterns in the source. For example, Acetolactate synthase → Acetolactate, ACT, AHASS1, AHASS2, ALS, Each, II, III, In, In Arabidopsis, InterPro, IPR002912, IPR004789, IPR012846, IPR027271, Most, NiKR-like C-terminal, Porphyra, Regulation, Such Another extracted example is Acetolactate synthase → Acetolactate, Enzyme Commission Code, Escherichia, FAD, In, InterPro, IPR012782, K-12, These, This. Use these groups to spot repeated connection types before inspecting the individual relationships.

Acetolactate synthase

Top relations

related to Regulation · 22
Acetolactate synthase → Acetolactate, ACT, AHASS1, AHASS2, ALS, Each, II, III, In, In Arabidopsis, InterPro, IPR002912, IPR004789, IPR012846, IPR027271, Most, NiKR-like C-terminal, Porphyra, Regulation, Such
related to Function · 10
Acetolactate synthase → Acetolactate, Enzyme Commission Code, Escherichia, FAD, In, InterPro, IPR012782, K-12, These, This
related to Structure · 9
Acetolactate synthase → ALS, Arabidopsis, C-terminal, DHS-like NAD/FAD-binding, In SCOP, N-terminal, The, Three, X-ray
related to Catalytic activity · 4
Acetolactate synthase → Acetolactate, All, The, This
Alt. names · 1
Acetolactate synthase → pyruvate:pyruvate acetaldehydetransferase (decarboxylating)
BRENDA · 1
Acetolactate synthase → enzyme data
CAS no. · 1
Acetolactate synthase → 9027-45-6
EC no. · 1
Acetolactate synthase → 2.2.1.6
ExPASy · 1
Acetolactate synthase → NiceZyme view
Gene Ontology · 1
Acetolactate synthase → AmiGO / QuickGO

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

als enzyme acetolactate synthase amino catalytic protein acids arabidopsis pyruvate activity operon structure also acid found plants branched-chain valine leucine

Acetolactate synthase relationships Subject–Predicate–Object triples

TTTA extracted 60 structured relationships around Acetolactate synthase. Examples in this analysis include Acetolactate synthase → Alt. names → pyruvate:pyruvate acetaldehydetransferase (decarboxylating) and Acetolactate synthase → BRENDA → enzyme data. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Acetolactate synthaseAlt. namespyruvate:pyruvate acetaldehydetransferase (decarboxylating)1.00infobox
Acetolactate synthaseBRENDAenzyme data1.00infobox
Acetolactate synthaseCAS no.9027-45-61.00infobox
Acetolactate synthaseEC no.2.2.1.61.00infobox
Acetolactate synthaseExPASyNiceZyme view1.00infobox
Acetolactate synthaseGene OntologyAmiGO / QuickGO1.00infobox
Acetolactate synthaseKEGGenzyme entry1.00infobox
Acetolactate synthaseMetaCycmetabolic pathway1.00infobox
Acetolactate synthaseNCBIproteins1.00infobox
Acetolactate synthasePDB structuresRCSB PDB PDBe PDBsum1.00infobox
Acetolactate synthasePMCarticles1.00infobox
Acetolactate synthasePubMedarticles1.00infobox
Acetolactate synthaseRheareactions1.00infobox
Acetolactate synthaseSearchSearchPMCarticlesPubMedarticlesNCBIproteins1.00infobox
Acetolactate synthaseis atransketolase0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Acetolactate synthase bring nearby vocabulary together. In this analysis, examples include Synthase, Known and Enzyme. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Acetolactate synthase
    • Synthase
    • Known
    • Enzyme
    • Acid
    • Also
    • Involved
    • Acetohydroxyacid
    • Domain
    • Interpro
    • Leucine
    • Structure
    • Thaliana
  • acetolactate synthase
    • Synthase
    • Known
    • Enzyme
    • Acid
    • Also
    • Involved
    • Acetohydroxyacid
    • Domain
    • Interpro
    • Leucine
    • Structure
    • Thaliana
  • enzyme
    • Also
    • Residues
    • Catalytic
    • Synthase
    • Known
    • Acid
    • Coli
    • Involved
    • Pyruvate
    • Ahas
    • Domain
    • Metabolic
  • acetolactate
    • Synthase
    • Known
    • Enzyme
    • Acid
    • Also
    • Involved
    • Acetohydroxyacid
    • Domain
    • Interpro
    • Leucine
    • Structure
    • Three
  • catalytic activity
    • Residues
    • Activity
    • Arabidopsis
    • Catalytic
    • Thaliana
    • Enzyme
    • Involved
    • Specific
    • Metsulfuron-methyl
    • Synthase
    • Herbicide
    • Inhibitors
  • arabidopsis thaliana
    • Metsulfuron-methyl
    • Arabidopsis
    • Thaliana
    • Herbicide
    • Catalytic
    • Acetohydroxyacid
    • Protein
    • Inhibitors
    • Metabolic
    • Structure
    • Residues
    • Activity
  • catalytic site
    • Residues
    • Activity
    • Arabidopsis
    • Thaliana
    • Enzyme
    • Involved
    • Specific
    • Synthase
    • Metsulfuron-methyl
    • Herbicide
    • Inhibitors
    • Interpro
  • branched-chain amino acids
    • Amino
    • Branched-chain
    • Involved
    • Isoleucine
    • Leucine
    • Valine
    • Inhibitors
    • Three
    • Als
    • Inhibition
    • Plants
    • Activity

Connections between topic areas Semantic bridges

For Acetolactate synthase, one of the stronger structural bridges in this analysis connects Acetolactate synthase with Inhibitors. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Acetolactate synthaseInhibitors · splits 36 ⟂ 15
Acetolactate synthaseRegulation · splits 39 ⟂ 12
Acetolactate synthaseStructure · splits 45 ⟂ 6
Acetolactate synthaseOverview · splits 46 ⟂ 5
Acetolactate synthaseFunction · splits 47 ⟂ 4
Acetolactate synthaseCatalytic activity · splits 47 ⟂ 4
Acetolactate synthaseInteractions · splits 47 ⟂ 4

Map overview Semantic statistics

Acetolactate synthase

Nodes51
Edges50
Triples60
Avg. degree1.96
Density0.039216
Components1

Source & methodology

TTTA analyzes the structure around Acetolactate synthase to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Standards, Inhibitors & Regulation, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Acetolactate synthase · EN edition · Analysis: TopicsToTalkAbout

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