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ABL2: Interactions, Function & Overview

Tyrosine-protein kinase ABL2 also known as Abelson-related gene (Arg) is an enzyme that in humans is encoded by the ABL2 gene.

Language: English [EN]
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ABL2 topic overview

The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around ABL2.

Related topics
13
Source areas
3
Connected nodes
16
Extracted relationships
128
Concept neighborhoods
10
Bridge connections
16

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 7 topics
Function · 4 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.10.2
Aliases
ABL2, ABLL, ARG, ABL proto-oncogene 2, non-receptor tyrosine kinase
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2ECD, 2KK1, 2XYN, 3GVU, 3HMI, 3ULR, 4EIH
Band
1q25.2 · 1 G3|1 67.71 cM
Bgee
tendon of biceps brachii · buccal mucosa cell · sural nerve · visceral pleura · parietal pleura
BioGPS
More reference expression data

Suggested research paths

A focused starting point derived from the topic graph, ranked independently of the source article order.

Start with these areas

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How ABL2 connects Entity context

The extracted context around ABL2 shows recurring relationship patterns in the source. For example, ABL2 → actin cytoskeleton, actin filament binding, actin monomer binding, ATP binding, cell adhesion, cell differentiation, cellular response to retinoic acid, cytoplasm, cytoskeleton, cytosol, exploration behavior, extrinsic component of cytoplasmic side of plasma membrane, innate immune response, kinase activity, magnesium ion binding, manganese ion binding, metal ion binding, negative regulation of Rho protein signal transduction, non-membrane spanning protein tyrosine kinase activity, nucleotide binding Another extracted example is ABL2 → Brodmann area 23, buccal mucosa cell, cerebellar vermis, endothelial cell of lymphatic vessel, foot, hand, lumbar subsegment of spinal cord, middle temporal gyrus, otolith organ, parietal pleura, primary oocyte, Rostral migratory stream, secondary oocyte, sural nerve, tendon of biceps brachii, tibia, utricle, visceral pleura, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

ABL2

Top relations

Gene ontology · 42
ABL2 → actin cytoskeleton, actin filament binding, actin monomer binding, ATP binding, cell adhesion, cell differentiation, cellular response to retinoic acid, cytoplasm, cytoskeleton, cytosol, exploration behavior, extrinsic component of cytoplasmic side of plasma membrane, innate immune response, kinase activity, magnesium ion binding, manganese ion binding, metal ion binding, negative regulation of Rho protein signal transduction, non-membrane spanning protein tyrosine kinase activity, nucleotide binding
Bgee · 19
ABL2 → Brodmann area 23, buccal mucosa cell, cerebellar vermis, endothelial cell of lymphatic vessel, foot, hand, lumbar subsegment of spinal cord, middle temporal gyrus, otolith organ, parietal pleura, primary oocyte, Rostral migratory stream, secondary oocyte, sural nerve, tendon of biceps brachii, tibia, utricle, visceral pleura, zygote
RNA expression pattern · 19
ABL2 → Brodmann area 23, buccal mucosa cell, cerebellar vermis, endothelial cell of lymphatic vessel, foot, hand, lumbar subsegment of spinal cord, middle temporal gyrus, otolith organ, parietal pleura, primary oocyte, Rostral migratory stream, secondary oocyte, sural nerve, tendon of biceps brachii, tibia, utricle, visceral pleura, zygote
related to External links · 10
ABL2 → Abelson, ABL2 Info, Cell Migration GatewayHuman ABL2, Genes, Leukemia, Medicine Medical Subject Headings, MeSH, National Library, UCSC Genome Browser, Virus
related to Interactions · 7
ABL2 → Abl, ABL1, Catalase, SH3, Sorbin, SORBS2, The
related to Function · 6
ABL2 → ABL1, KRAS, SH2, SH3, The, The ABL2
Band · 2
ABL2 → 1 G3|1 67.71 cM, 1q25.2
Chr. · 2
ABL2 → Chromosome 1 (human), Chromosome 1 (mouse)
End · 2
ABL2 → 156,477,138 bp, 179,229,684 bp
2.7.10.2 · 1
ABL2 → ↗

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene human bp chr band kinase chromosome location enzyme tyrosine abl also known encoded mouse cell expressed protein arg function

ABL2 relationships Subject–Predicate–Object triples

TTTA extracted 128 structured relationships around ABL2. Examples in this analysis include ABL2 → 2.7.10.2 → ↗ and ABL2 → Aliases → ABL2, ABLL, ARG, ABL proto-oncogene 2, non-receptor tyrosine kinase. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
ABL22.7.10.21.00infobox
ABL2AliasesABL2, ABLL, ARG, ABL proto-oncogene 2, non-receptor tyrosine kinase1.00infobox
ABL2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2ECD, 2KK1, 2XYN, 3GVU, 3HMI, 3ULR, 4EIH1.00infobox
ABL2Band1q25.21.00infobox
ABL2Band1 G3|1 67.71 cM1.00infobox
ABL2Bgeetendon of biceps brachii1.00infobox
ABL2Bgeebuccal mucosa cell1.00infobox
ABL2Bgeesural nerve1.00infobox
ABL2Bgeevisceral pleura1.00infobox
ABL2Bgeeparietal pleura1.00infobox
ABL2Bgeemiddle temporal gyrus1.00infobox
ABL2BgeeBrodmann area 231.00infobox
ABL2Bgeetibia1.00infobox
ABL2Bgeesecondary oocyte1.00infobox
ABL2Bgeecerebellar vermis1.00infobox
ABL2BgeeRostral migratory stream1.00infobox
ABL2Bgeeprimary oocyte1.00infobox
ABL2Bgeeotolith organ1.00infobox
ABL2Bgeezygote1.00infobox
ABL2Bgeeutricle1.00infobox
ABL2Bgeeendothelial cell of lymphatic vessel1.00infobox
ABL2Bgeehand1.00infobox
ABL2Bgeelumbar subsegment of spinal cord1.00infobox
ABL2Bgeefoot1.00infobox
ABL2BioGPSMore reference expression data1.00infobox
ABL2Chr.Chromosome 1 (human)1.00infobox
ABL2Chr.Chromosome 1 (mouse)1.00infobox
ABL2DatabasesNCBI: entry; OMA: entry1.00infobox
ABL2End179,229,684 bp1.00infobox
ABL2End156,477,138 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around ABL2 bring nearby vocabulary together. In this analysis, examples include Gene, Cell and Expressed. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • ABL2
    • Gene
    • Cell
    • Expressed
    • Kinase
    • Location
    • Human
    • Activity
    • Arg
    • Expression
    • Function
    • Links
    • Search
  • abl2
    • Gene
    • Cell
    • Expressed
    • Kinase
    • Location
    • Human
    • Activity
    • Arg
    • Expression
    • Function
    • Links
    • Search
  • gene
    • Human
    • Location
    • Cell
    • Encoded
    • Known
    • Protein
    • Abl
    • Chromosome
    • Kinase
    • Bp
    • Chr
    • Abl1
  • tyrosine kinase
    • Kinase
    • Tyrosine
    • Activity
    • Function
    • Search
    • Arg
    • Chromosome
    • Enzyme
    • Location
    • Bp
    • Chr
    • External
  • abl1
    • Protein
    • Activity
    • End
    • Expression
    • Function
    • G3
    • Human
    • Mouse
    • Search
    • Also
    • Cell
    • Encoded
  • function
    • Activity
    • Search
    • Tyrosine
    • Chromosome
    • Kinase
    • Location
    • Bp
    • Chr
    • Abl1
    • End
    • Expression
    • G3
  • enzyme
    • Kinase
    • External
    • Activity
    • Catalase
    • Function
    • Humans
    • Links
    • Search
    • Encoded
    • Known
    • Tyrosine
    • Gene
  • sorbs2
    • Catalase
    • Humans
    • Sh3
    • Also
    • Encoded
    • Known
    • Protein
    • Abl
    • Gene
    • Abl2

Connections between topic areas Semantic bridges

For ABL2, one of the stronger structural bridges in this analysis connects ABL2 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
ABL2Interactions · splits 9 ⟂ 8
ABL2Function · splits 12 ⟂ 5
ABL2Overview · splits 14 ⟂ 3

Map overview Semantic statistics

ABL2

Nodes17
Edges16
Triples128
Avg. degree1.88
Density0.117647
Components1

Source & methodology

TTTA analyzes the structure around ABL2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — ABL2 · EN edition · Analysis: TopicsToTalkAbout

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