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Proteiny rodiny STAT (z ang. "Signal Transducer and Activator of Transcription") mají duální roli přenašečů signálu a transkripčních faktorů. Tím, že ovlivňují diferenciaci, proliferaci, migraci a apoptózu buněk se podílejí na udržení humorální a imunitní homeostázy a na embryonálním vývoji. Doposud bylo u savců popsáno sedm členů této rodiny (STAT1…
Signální dráha, Funkce & Overview
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stat proteiny rodiny stat3 stat5a stat4 diferenciaci stat5b stat6 faktorů buněk podílejí vývoji il-4 il-12 proliferaci migraci apoptózu homeostázy savců
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| STAT protein | related to Funkce | Ačkoliv | 0.60 | section |
| STAT protein | related to Funkce | Jednotlivé STAT | 0.60 | section |
| STAT protein | related to Funkce | Odpověď | 0.60 | section |
| STAT protein | related to Funkce | IL-12 | 0.60 | section |
| STAT protein | related to Funkce | STAT4 | 0.60 | section |
| STAT protein | related to Funkce | T-lymfocytu | 0.60 | section |
| STAT protein | related to Funkce | Th1 | 0.60 | section |
| STAT protein | related to Funkce | IL-4 | 0.60 | section |
| STAT protein | related to Funkce | STAT6 | 0.60 | section |
| STAT protein | related to Funkce | Th2 | 0.60 | section |
| STAT protein | related to Funkce | STAT3 | 0.60 | section |
| STAT protein | related to Funkce | Th17 | 0.60 | section |
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