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STAT1

Přenašeč signálu a aktivátor transkripce 1 (z anglického: „Signal transducer and activator of transcription 1“ = STAT1), je transkripční faktor, který je v lidském genomu kódován STAT1 genem. Je členem STAT proteinové rodiny a účastní se JAK/STAT signalizace.

Mutace STAT1, Funkce & Overview

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Overview

Funkce

Mutace STAT1

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Map overview Semantic statistics

STAT1

Nodes15
Edges14
Triples76
Avg. degree1.87
Density0.133333
Components1

How this topic connects Entity context

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STAT1

Top relations

related to Gain of function · 27
STAT1 → Candida, CMC, DNA, Dále, Herpesviridae, IgE, IL-17A, Jak, Kandidou, Kvůli, Mutace, Mycobacterium, Mykobakteriální, N-koncové, Pacienti, Pokud, Pomocí, SH2, Staphylococcus, T-buněk
related to Funkce · 24
STAT1 → EGF, Epidermální, Existují, Fosforylují, IFNa, IFNb, IFNg, IL-6, Interferon, Interferonem, Interferony, Interleukin, ISGF3G/IRF-9, Jak, JAK1, PDGF, Regulačním, Růstový, STAT, STAT2
related to Loss of function · 20
STAT1 → BCG, Bylo, CD25, CD4, Dalším, Dále, Existují, IFNa, IFNg, III, IL-12, IL-27, Jednalo, MSMD, První, Při, Ta, Tito, Ve, Vědci
related to Mutace STAT1 · 5
STAT1 → GOF, LOF, Mutace, Obě, Opakované

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Important terminology

jako jsou cmc mutace může ifng odpověď deficience pacienti stat jak of typu tedy symptomy infekce ifna autozomálně recesivní trpí

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
STAT1related to FunkceVšechny STAT0.60section
STAT1related to FunkceZejména STAT10.60section
STAT1related to FunkceInterferon0.60section
STAT1related to FunkceIFNa0.60section
STAT1related to FunkceIFNg0.60section
STAT1related to FunkceEpidermální0.60section
STAT1related to FunkceEGF0.60section
STAT1related to FunkceRůstový0.60section
STAT1related to FunkcePDGF0.60section
STAT1related to FunkceInterleukin0.60section
STAT1related to FunkceIL-60.60section
STAT1related to FunkceInterferony0.60section

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