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ZW10: Function, Interactions & Overview

Centromere/kinetochore protein zw10 homolog is a protein that in humans is encoded by the ZW10 gene. This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. The encoded protein binds to centromeres during the prophase, metaphase, and early anaphase cell division stages and to…

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ZW10 topic overview

The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around ZW10.

Related topics
29
Source areas
3
Connected nodes
32
Extracted relationships
115
Concept neighborhoods
18
Bridge connections
32

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 16 topics
Overview · 10 topics
Interactions · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
ZW10, HKNTC1AP, zw10 kinetochore protein
Band
11q23.2 · 9|9 A5.3
Bgee
tibialis anterior muscle · ventricular zone · secondary oocyte · mucosa of ileum · gastrocnemius muscle
BioGPS
More reference expression data
Chr.
Chromosome 11 (human) · Chromosome 9 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How ZW10 connects Entity context

The extracted context around ZW10 shows recurring relationship patterns in the source. For example, ZW10 → cell cycle, cell division, centromeric DNA binding, chromosome, chromosome, centromeric region, cytoplasm, cytoskeleton, cytosol, Dsl1/NZR complex, endoplasmic reticulum, endoplasmic reticulum membrane, endoplasmic reticulum to Golgi vesicle-mediated transport, establishment of mitotic spindle orientation, Golgi organization, kinetochore, kinetochore microtubule, meiosis, membrane, mitotic cell cycle, mitotic cell cycle checkpoint signaling Another extracted example is ZW10 → Achilles tendon, cartilage tissue, condyle, fetal liver hematopoietic progenitor cell, fossa, ganglionic eminence, gastrocnemius muscle, gastrula, hair follicle, maxillary prominence, motor neuron, mucosa of ileum, primary oocyte, primitive streak, secondary oocyte, skin of leg, submandibular gland, testicle, tibialis anterior muscle, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

ZW10

Top relations

Gene ontology · 36
ZW10 → cell cycle, cell division, centromeric DNA binding, chromosome, chromosome, centromeric region, cytoplasm, cytoskeleton, cytosol, Dsl1/NZR complex, endoplasmic reticulum, endoplasmic reticulum membrane, endoplasmic reticulum to Golgi vesicle-mediated transport, establishment of mitotic spindle orientation, Golgi organization, kinetochore, kinetochore microtubule, meiosis, membrane, mitotic cell cycle, mitotic cell cycle checkpoint signaling
Bgee · 20
ZW10 → Achilles tendon, cartilage tissue, condyle, fetal liver hematopoietic progenitor cell, fossa, ganglionic eminence, gastrocnemius muscle, gastrula, hair follicle, maxillary prominence, motor neuron, mucosa of ileum, primary oocyte, primitive streak, secondary oocyte, skin of leg, submandibular gland, testicle, tibialis anterior muscle, ventricular zone
RNA expression pattern · 20
ZW10 → Achilles tendon, cartilage tissue, condyle, fetal liver hematopoietic progenitor cell, fossa, ganglionic eminence, gastrocnemius muscle, gastrula, hair follicle, maxillary prominence, motor neuron, mucosa of ileum, primary oocyte, primitive streak, secondary oocyte, skin of leg, submandibular gland, testicle, tibialis anterior muscle, ventricular zone
related to Function · 18
ZW10 → Dominant-negative ZW10, Drosophila, Golgi, In, It, Mad2, RNAi, Rod, Rod-Zw10-Zwilch, Rough, RZZ, SAC, SNARE-mediated ER-Golgi, The, These, Zeste, ZW10 RNA, ZW10 RNAi
Band · 2
ZW10 → 11q23.2, 9|9 A5.3
Chr. · 2
ZW10 → Chromosome 11 (human), Chromosome 9 (mouse)
End · 2
ZW10 → 113,773,735 bp, 48,990,075 bp
Aliases · 1
ZW10 → ZW10, HKNTC1AP, zw10 kinetochore protein
BioGPS · 1
ZW10 → More reference expression data
Databases · 1
ZW10 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

chromosome protein kinetochore gene bp chr human band checkpoint 11 metaphase segregation cell division location involved encoded cytoplasmic dynein mouse

ZW10 relationships Subject–Predicate–Object triples

TTTA extracted 115 structured relationships around ZW10. Examples in this analysis include ZW10 → Aliases → ZW10, HKNTC1AP, zw10 kinetochore protein and ZW10 → Band → 11q23.2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
ZW10AliasesZW10, HKNTC1AP, zw10 kinetochore protein1.00infobox
ZW10Band11q23.21.00infobox
ZW10Band9|9 A5.31.00infobox
ZW10Bgeetibialis anterior muscle1.00infobox
ZW10Bgeeventricular zone1.00infobox
ZW10Bgeesecondary oocyte1.00infobox
ZW10Bgeemucosa of ileum1.00infobox
ZW10Bgeegastrocnemius muscle1.00infobox
ZW10BgeeAchilles tendon1.00infobox
ZW10Bgeecartilage tissue1.00infobox
ZW10Bgeeskin of leg1.00infobox
ZW10Bgeeganglionic eminence1.00infobox
ZW10Bgeetesticle1.00infobox
ZW10Bgeegastrula1.00infobox
ZW10Bgeeprimary oocyte1.00infobox
ZW10Bgeecondyle1.00infobox
ZW10Bgeesubmandibular gland1.00infobox
ZW10Bgeefossa1.00infobox
ZW10Bgeefetal liver hematopoietic progenitor cell1.00infobox
ZW10Bgeeprimitive streak1.00infobox
ZW10Bgeehair follicle1.00infobox
ZW10Bgeemaxillary prominence1.00infobox
ZW10Bgeemotor neuron1.00infobox
ZW10BioGPSMore reference expression data1.00infobox
ZW10Chr.Chromosome 11 (human)1.00infobox
ZW10Chr.Chromosome 9 (mouse)1.00infobox
ZW10DatabasesNCBI: entry; OMA: entry1.00infobox
ZW10End113,773,735 bp1.00infobox
ZW10End48,990,075 bp1.00infobox
ZW10EnsemblENSG000000868271.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around ZW10 bring nearby vocabulary together. In this analysis, examples include Kinetochore, Gene and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • ZW10
    • Kinetochore
    • Gene
    • Protein
    • Function
    • Rna
    • Golgi
    • Location
    • Checkpoint
    • Human
    • Metaphase
    • Bp
    • Chr
  • zw10
    • Kinetochore
    • Gene
    • Protein
    • Function
    • Rna
    • Golgi
    • Location
    • Checkpoint
    • Human
    • Metaphase
    • Bp
    • Chr
  • protein
    • Cell
    • Division
    • Function
    • Chromosome
    • Involved
    • Location
    • Segregation
    • Zw10
    • Human
    • Metaphase
    • Bp
    • Chr
  • gene
    • Protein
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Kinetochore
    • A5
    • End
    • Function
    • Mouse
    • Cell
  • chromosome segregation
    • Human
    • Bp
    • Chr
    • Gene
    • Location
    • Segregation
    • Band
    • Protein
    • A5
    • End
    • Function
    • Mitosis
  • cell division
    • Division
    • Protein
    • Involved
    • Segregation
    • Metaphase
    • Gene
    • Kinetochore
    • Mitotic
    • Chromosome
    • A5
    • Anaphase
    • Complex
  • metaphase
    • Checkpoint
    • Microtubule
    • Spindle
    • Kinetochores
    • Protein
    • Mitotic
    • Zw10
    • A5
    • Complex
    • End
    • Function
    • Mitosis
  • kinetochore
    • Protein
    • Metaphase
    • Zw10
    • Gene
    • Encoded
    • Function
    • Cell
    • Division
    • Location
    • Checkpoint
    • Human
    • Bp

Connections between topic areas Semantic bridges

For ZW10, one of the stronger structural bridges in this analysis connects ZW10 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
ZW10Function · splits 16 ⟂ 17
ZW10Overview · splits 22 ⟂ 11
ZW10Interactions · splits 29 ⟂ 4

Map overview Semantic statistics

ZW10

Nodes33
Edges32
Triples115
Avg. degree1.94
Density0.060606
Components1

Source & methodology

TTTA analyzes the structure around ZW10 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — ZW10 · EN edition · Analysis: TopicsToTalkAbout

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