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Xbra

Xbra is a homologue of Brachyury (T) gene for Xenopus. It is a transcription activator involved in vertebrate gastrulation which controls posterior mesoderm patterning and notochord differentiation by activating transcription of genes expressed throughout mesoderm. The effects of Xbra is concentration dependent where concentration gradient controls the…

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Xbra

Nodes14
Edges13
Triples3
Avg. degree1.86
Density0.142857
Components1

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Xbra

Top relations

is a · 1
Xbra → homologue of Brachyury

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Important terminology

mesoderm notochord transcription concentration fgf ventral two cell migration cells xenopus chordamesoderm controls posterior patterning differentiation development types expression factor

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Xbrais ahomologue of Brachyury0.90text
defective blastopore closureinstance ofThe injection of RNA encoding this construct has led to various birth defects0.80text
abnormal notochord differentiation in the developing embryoinstance ofThe injection of RNA encoding this construct has led to various birth defects0.80text

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