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VPS28: Function, Interactions & Overview

Vacuolar protein sorting-associated protein 28 homolog is a protein that in humans is encoded by the VPS28 gene.

Language: English [EN]
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VPS28 topic overview

The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around VPS28.

Related topics
7
Source areas
3
Connected nodes
10
Extracted relationships
89
Related term clusters
9
Bridge connections
10

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 4 topics
Overview · 2 topics
Interactions · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
VPS28, ESCRT-I subunit, VPS28 subunit of ESCRT-I
Band
8q24.3 · 15|15 D3
Bgee
right uterine tube · left testis · apex of heart · right lobe of thyroid gland · right ovary
BioGPS
More reference expression data
Chr.
Chromosome 8 (human) · Chromosome 15 (mouse)
Databases
NCBI: entry; OMA: entry

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How VPS28 connects Entity context

The extracted context around VPS28 shows recurring relationship patterns in the source. For example, VPS28 → cytoplasm, cytosol, early endosome, endosomal transport, endosome, endosome membrane, endosome transport via multivesicular body sorting pathway, ESCRT I complex, extracellular exosome, host cell, intracellular transport of virus, late endosome membrane, macroautophagy, membrane, multivesicular body assembly, negative regulation of protein ubiquitination, plasma membrane, positive regulation of protein catabolic process, positive regulation of ubiquitin-dependent endocytosis, protein binding Another extracted example is VPS28 → adrenal gland, ankle joint, anterior horn of spinal cord, apex of heart, central gray substance of midbrain, duodenum, facial motor nucleus, fundus, granulocyte, left lobe of thyroid gland, left ovary, left testis, nucleus of stria terminalis, right lobe of thyroid gland, right lung lobe, right ovary, right testis, right uterine tube, transitional epithelium of urinary bladder, vestibular membrane of cochlear duct. Use these groups to spot repeated connection types before inspecting the individual relationships.

VPS28

Top relations

Gene ontology · 28
VPS28 → cytoplasm, cytosol, early endosome, endosomal transport, endosome, endosome membrane, endosome transport via multivesicular body sorting pathway, ESCRT I complex, extracellular exosome, host cell, intracellular transport of virus, late endosome membrane, macroautophagy, membrane, multivesicular body assembly, negative regulation of protein ubiquitination, plasma membrane, positive regulation of protein catabolic process, positive regulation of ubiquitin-dependent endocytosis, protein binding
Bgee · 20
VPS28 → adrenal gland, ankle joint, anterior horn of spinal cord, apex of heart, central gray substance of midbrain, duodenum, facial motor nucleus, fundus, granulocyte, left lobe of thyroid gland, left ovary, left testis, nucleus of stria terminalis, right lobe of thyroid gland, right lung lobe, right ovary, right testis, right uterine tube, transitional epithelium of urinary bladder, vestibular membrane of cochlear duct
RNA expression pattern · 20
VPS28 → adrenal gland, ankle joint, anterior horn of spinal cord, apex of heart, central gray substance of midbrain, duodenum, facial motor nucleus, fundus, granulocyte, left lobe of thyroid gland, left ovary, left testis, nucleus of stria terminalis, right lobe of thyroid gland, right lung lobe, right ovary, right testis, right uterine tube, transitional epithelium of urinary bladder, vestibular membrane of cochlear duct
Band · 2
VPS28 → 15|15 D3, 8q24.3
Chr. · 2
VPS28 → Chromosome 15 (mouse), Chromosome 8 (human)
End · 2
VPS28 → 144,428,563 bp, 76,510,286 bp
Aliases · 1
VPS28 → VPS28, ESCRT-I subunit, VPS28 subunit of ESCRT-I
BioGPS · 1
VPS28 → More reference expression data
Databases · 1
VPS28 → NCBI: entry; OMA: entry
Ensembl · 1
VPS28 → ENSG00000160948 ENSG00000285339

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene chr human band protein chromosome sorting location escrt-i encoded mouse endosomal involved function vacuolar 428 563 end 144

VPS28 relationships Subject–Predicate–Object triples

TTTA extracted 89 structured relationships around VPS28. Examples in this analysis include VPS28 → Aliases → VPS28, ESCRT-I subunit, VPS28 subunit of ESCRT-I and VPS28 → Band → 8q24.3. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
VPS28AliasesVPS28, ESCRT-I subunit, VPS28 subunit of ESCRT-I1.00infobox
VPS28Band8q24.31.00infobox
VPS28Band15|15 D31.00infobox
VPS28Bgeeright uterine tube1.00infobox
VPS28Bgeeleft testis1.00infobox
VPS28Bgeeapex of heart1.00infobox
VPS28Bgeeright lobe of thyroid gland1.00infobox
VPS28Bgeeright ovary1.00infobox
VPS28Bgeeleft ovary1.00infobox
VPS28Bgeeduodenum1.00infobox
VPS28Bgeefundus1.00infobox
VPS28Bgeeright testis1.00infobox
VPS28Bgeeleft lobe of thyroid gland1.00infobox
VPS28Bgeeankle joint1.00infobox
VPS28Bgeefacial motor nucleus1.00infobox
VPS28Bgeeright lung lobe1.00infobox
VPS28Bgeecentral gray substance of midbrain1.00infobox
VPS28Bgeevestibular membrane of cochlear duct1.00infobox
VPS28Bgeeanterior horn of spinal cord1.00infobox
VPS28Bgeetransitional epithelium of urinary bladder1.00infobox
VPS28Bgeenucleus of stria terminalis1.00infobox
VPS28Bgeegranulocyte1.00infobox
VPS28Bgeeadrenal gland1.00infobox
VPS28BioGPSMore reference expression data1.00infobox
VPS28Chr.Chromosome 8 (human)1.00infobox
VPS28Chr.Chromosome 15 (mouse)1.00infobox
VPS28DatabasesNCBI: entry; OMA: entry1.00infobox
VPS28End144,428,563 bp1.00infobox
VPS28End76,510,286 bp1.00infobox
VPS28EnsemblENSG00000160948 ENSG000002853391.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around VPS28 bring nearby vocabulary together. In this analysis, examples include Function, Gene and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • VPS28
    • Function
    • Gene
    • Location
    • Chromosome
    • Human
    • Protein
    • Bp
    • Chr
    • Body
    • Cell
    • Endosome
    • Multivesicular
  • vps28
    • Function
    • Gene
    • Location
    • Chromosome
    • Human
    • Protein
    • Bp
    • Chr
    • Body
    • Cell
    • Endosome
    • Multivesicular
  • protein
    • Sorting
    • Complex
    • Endosomal
    • Gene
    • Involved
    • Subunits
    • Transport
    • Vacuolar
    • Encoded
    • Escrt-i
    • Vps28
    • Body
  • gene
    • Location
    • Chromosome
    • Human
    • Protein
    • Vps28
    • Bp
    • Chr
    • End
    • Function
    • Mouse
    • Vacuolar
    • Escrt-i
  • ubiquitinated protein
    • Sorting
    • Complex
    • Endosomal
    • Gene
    • Involved
    • Subunits
    • Transport
    • Vacuolar
    • Encoded
    • Escrt-i
    • Vps28
    • Body
  • tumor susceptibility gene 101
    • Location
    • Chromosome
    • Human
    • Protein
    • Vps28
    • Bp
    • Chr
    • End
    • Function
    • Mouse
    • Vacuolar
    • Escrt-i
  • vacuolar protein sorting 37
    • Sorting
    • Subunits
    • Transport
    • Complex
    • Endosomal
    • Gene
    • Involved
    • Vacuolar
    • Encoded
    • Escrt-i
    • Tsg101
    • Two
  • function
    • Location
    • Body
    • Cell
    • Chromosome
    • Endosome
    • Human
    • Multivesicular
    • Pathway
    • Via
    • Vps28
    • Bp
    • Chr

Connections between topic areas Semantic bridges

For VPS28, one of the stronger structural bridges in this analysis connects VPS28 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
VPS28 — Function · splits 6 ⟂ 5
VPS28 — Overview · splits 8 ⟂ 3

Map overview Semantic statistics

VPS28

Nodes11
Edges10
Triples89
Avg. degree1.82
Density0.181818
Components1

Source & methodology

TTTA analyzes the structure around VPS28 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — VPS28 · EN edition · Analysis: TopicsToTalkAbout

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