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Ubiquitin carboxyl-terminal hydrolase 8 is an enzyme that in humans is encoded by the USP8 gene.
The analysis highlights Interactions and Overview as prominent areas in the source structure around USP8.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around USP8 shows recurring relationship patterns in the source. For example, USP8 → cadherin binding, cell cycle, cell population proliferation, cellular response to dexamethasone stimulus, cellular response to nerve growth factor stimulus, cysteine-type endopeptidase activity, cysteine-type peptidase activity, cytoplasm, cytosol, dendritic spine, early endosome, endosome, endosome membrane, endosome organization, extrinsic component of endosome membrane, extrinsic component of plasma membrane, glutamatergic synapse, hydrolase activity, membrane, midbody Another extracted example is USP8 → Achilles tendon, caput epididymis, corpus epididymis, deep cerebellar nuclei, epithelium of colon, gallbladder, genital tubercle, medial vestibular nucleus, monocyte, rectum, right kidney, seminiferous tubule, spermatid, spermatocyte, stroma of bone marrow, sural nerve, tail of embryo, testicle, ventricular zone, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
bp chr human band gene chromosome 15 location enzyme mouse ubiquitin hydrolase peptidase search activity 514 421 end 50 601
TTTA extracted 107 structured relationships around USP8. Examples in this analysis include USP8 → 3.4.19.12 → ↗ and USP8 → Aliases → USP8, HumORF8, SPG59, UBPY, ubiquitin specific peptidase 8, PITA4. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| USP8 | 3.4.19.12 | ↗ | 1.00 | infobox |
| USP8 | Aliases | USP8, HumORF8, SPG59, UBPY, ubiquitin specific peptidase 8, PITA4 | 1.00 | infobox |
| USP8 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WHB, 2A9U, 2GFO, 2GWF, 3N3K | 1.00 | infobox |
| USP8 | Band | 15q21.2 | 1.00 | infobox |
| USP8 | Band | 2|2 F1 | 1.00 | infobox |
| USP8 | Bgee | Achilles tendon | 1.00 | infobox |
| USP8 | Bgee | sural nerve | 1.00 | infobox |
| USP8 | Bgee | epithelium of colon | 1.00 | infobox |
| USP8 | Bgee | ventricular zone | 1.00 | infobox |
| USP8 | Bgee | testicle | 1.00 | infobox |
| USP8 | Bgee | rectum | 1.00 | infobox |
| USP8 | Bgee | monocyte | 1.00 | infobox |
| USP8 | Bgee | caput epididymis | 1.00 | infobox |
| USP8 | Bgee | corpus epididymis | 1.00 | infobox |
| USP8 | Bgee | gallbladder | 1.00 | infobox |
| USP8 | Bgee | spermatid | 1.00 | infobox |
| USP8 | Bgee | seminiferous tubule | 1.00 | infobox |
| USP8 | Bgee | spermatocyte | 1.00 | infobox |
| USP8 | Bgee | tail of embryo | 1.00 | infobox |
| USP8 | Bgee | genital tubercle | 1.00 | infobox |
| USP8 | Bgee | right kidney | 1.00 | infobox |
| USP8 | Bgee | stroma of bone marrow | 1.00 | infobox |
| USP8 | Bgee | zygote | 1.00 | infobox |
| USP8 | Bgee | deep cerebellar nuclei | 1.00 | infobox |
| USP8 | Bgee | medial vestibular nucleus | 1.00 | infobox |
| USP8 | BioGPS | n/a | 1.00 | infobox |
| USP8 | Chr. | Chromosome 15 (human) | 1.00 | infobox |
| USP8 | Chr. | Chromosome 2 (mouse) | 1.00 | infobox |
| USP8 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| USP8 | End | 50,514,421 bp | 1.00 | infobox |
The concept neighborhoods around USP8 bring nearby vocabulary together. In this analysis, examples include Gene, Activity and Enzyme. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For USP8, one of the stronger structural bridges in this analysis connects USP8 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around USP8 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — USP8 · EN edition · Analysis: TopicsToTalkAbout