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USP8

Ubiquitin carboxyl-terminal hydrolase 8 is an enzyme that in humans is encoded by the USP8 gene.

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3.4.19.12
Aliases
USP8, HumORF8, SPG59, UBPY, ubiquitin specific peptidase 8, PITA4
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WHB, 2A9U, 2GFO, 2GWF, 3N3K
Band
15q21.2 · 2|2 F1
Bgee
Achilles tendon · sural nerve · epithelium of colon · ventricular zone · testicle
BioGPS
n/a

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USP8

Nodes8
Edges7
Triples107
Avg. degree1.75
Density0.25
Components1

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USP8

Top relations

Gene ontology · 38
USP8 → cadherin binding, cell cycle, cell population proliferation, cellular response to dexamethasone stimulus, cellular response to nerve growth factor stimulus, cysteine-type endopeptidase activity, cysteine-type peptidase activity, cytoplasm, cytosol, dendritic spine, early endosome, endosome, endosome membrane, endosome organization, extrinsic component of endosome membrane, extrinsic component of plasma membrane, glutamatergic synapse, hydrolase activity, membrane, midbody
Bgee · 20
USP8 → Achilles tendon, caput epididymis, corpus epididymis, deep cerebellar nuclei, epithelium of colon, gallbladder, genital tubercle, medial vestibular nucleus, monocyte, rectum, right kidney, seminiferous tubule, spermatid, spermatocyte, stroma of bone marrow, sural nerve, tail of embryo, testicle, ventricular zone, zygote
RNA expression pattern · 20
USP8 → Achilles tendon, caput epididymis, corpus epididymis, deep cerebellar nuclei, epithelium of colon, gallbladder, genital tubercle, medial vestibular nucleus, monocyte, rectum, right kidney, seminiferous tubule, spermatid, spermatocyte, stroma of bone marrow, sural nerve, tail of embryo, testicle, ventricular zone, zygote
Band · 2
USP8 → 15q21.2, 2|2 F1
Chr. · 2
USP8 → Chromosome 15 (human), Chromosome 2 (mouse)
End · 2
USP8 → 126,601,217 bp, 50,514,421 bp
related to Diseases · 2
USP8 → In, Morbus Cushing's
related to Interactions · 2
USP8 → RNF41, STAM2
3.4.19.12 · 1
USP8 → ↗
Aliases · 1
USP8 → USP8, HumORF8, SPG59, UBPY, ubiquitin specific peptidase 8, PITA4

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Important terminology

bp chr human band gene chromosome 15 location enzyme mouse ubiquitin hydrolase peptidase search activity 514 421 end 50 601

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
USP83.4.19.121.00infobox
USP8AliasesUSP8, HumORF8, SPG59, UBPY, ubiquitin specific peptidase 8, PITA41.00infobox
USP8Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WHB, 2A9U, 2GFO, 2GWF, 3N3K1.00infobox
USP8Band15q21.21.00infobox
USP8Band2|2 F11.00infobox
USP8BgeeAchilles tendon1.00infobox
USP8Bgeesural nerve1.00infobox
USP8Bgeeepithelium of colon1.00infobox
USP8Bgeeventricular zone1.00infobox
USP8Bgeetesticle1.00infobox
USP8Bgeerectum1.00infobox
USP8Bgeemonocyte1.00infobox
USP8Bgeecaput epididymis1.00infobox
USP8Bgeecorpus epididymis1.00infobox
USP8Bgeegallbladder1.00infobox
USP8Bgeespermatid1.00infobox
USP8Bgeeseminiferous tubule1.00infobox
USP8Bgeespermatocyte1.00infobox
USP8Bgeetail of embryo1.00infobox
USP8Bgeegenital tubercle1.00infobox
USP8Bgeeright kidney1.00infobox
USP8Bgeestroma of bone marrow1.00infobox
USP8Bgeezygote1.00infobox
USP8Bgeedeep cerebellar nuclei1.00infobox
USP8Bgeemedial vestibular nucleus1.00infobox
USP8BioGPSn/a1.00infobox
USP8Chr.Chromosome 15 (human)1.00infobox
USP8Chr.Chromosome 2 (mouse)1.00infobox
USP8DatabasesNCBI: entry; OMA: entry1.00infobox
USP8End50,514,421 bp1.00infobox

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