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Thermogenin

Thermogenin (called uncoupling protein by its discoverers and now known as uncoupling protein 1, or UCP1) is a mitochondrial carrier protein found in brown adipose tissue (BAT). It is used to generate heat by non-shivering thermogenesis, and makes a quantitatively important contribution to countering heat loss in babies which would otherwise occur due to…

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Aliases
UCP1, SLC25A7, UCP, uncoupling protein 1
Band
4q31.1 · 8 C2|8 39.65 cM
Bgee
testicle · parietal pleura · face · mucosa of nose · Ventricular system of neuraxis
BioGPS
More reference expression data
Chr.
Chromosome 4 (human) · Chromosome 8 (mouse)
Databases
NCBI: entry; OMA: entry

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Thermogenin

Nodes53
Edges52
Triples116
Avg. degree1.96
Density0.037736
Components1

How this topic connects Entity context

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Thermogenin

Top relations

Gene ontology · 27
Thermogenin → adaptive thermogenesis, brown fat cell differentiation, cardiolipin binding, cellular response to fatty acid, cellular response to hormone stimulus, cellular response to reactive oxygen species, diet induced thermogenesis, integral component of membrane, ion transport, long-chain fatty acid binding, membrane, mitochondrial envelope, mitochondrial inner membrane, mitochondrial membranes, mitochondrial transmembrane transport, mitochondrial transport, mitochondrion, oxidative phosphorylation uncoupler activity, positive regulation of cold-induced thermogenesis, proton transmembrane transport
Bgee · 20
Thermogenin → ascending aorta, brown adipose tissue, carotid body, face, intercostal muscle, lactiferous gland, mammary gland, mucosa of nose, olfactory zone of nasal mucosa, parietal pleura, parotid gland, placenta, sternocleidomastoid muscle, superior surface of tongue, testicle, trachea, tunica adventitia of aorta, tunica media of zone of aorta, Ventricular system of neuraxis, ventricular zone
RNA expression pattern · 20
Thermogenin → ascending aorta, brown adipose tissue, carotid body, face, intercostal muscle, lactiferous gland, mammary gland, mucosa of nose, olfactory zone of nasal mucosa, parietal pleura, parotid gland, placenta, sternocleidomastoid muscle, superior surface of tongue, testicle, trachea, tunica adventitia of aorta, tunica media of zone of aorta, Ventricular system of neuraxis, ventricular zone
related to Mechanism · 16
Thermogenin → Active, ADP, AMP, ATP, Beta-3, During, Fatty, GDP, Norepinephrine, Sympathetic, The, They, This, UCP, UCP1, UCP1-mediated
related to Evolution · 6
Thermogenin → It, Recent, The UCP1, This, UCP1, While UCP1
related to External links · 5
Thermogenin → BBC, Medicine Medical Subject Headings, MeSH, National Library, Seaweed
Band · 2
Thermogenin → 4q31.1, 8 C2|8 39.65 cM
Chr. · 2
Thermogenin → Chromosome 4 (human), Chromosome 8 (mouse)
End · 2
Thermogenin → 140,568,961 bp, 84,025,081 bp
Aliases · 1
Thermogenin → UCP1, SLC25A7, UCP, uncoupling protein 1

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Important terminology

ucp1 protein brown bp membrane gene human thermogenesis uncoupling mitochondrial adipose tissue chr band proton heat chromosome fatty placental acids

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
ThermogeninAliasesUCP1, SLC25A7, UCP, uncoupling protein 11.00infobox
ThermogeninBand4q31.11.00infobox
ThermogeninBand8 C2|8 39.65 cM1.00infobox
ThermogeninBgeetesticle1.00infobox
ThermogeninBgeeparietal pleura1.00infobox
ThermogeninBgeeface1.00infobox
ThermogeninBgeemucosa of nose1.00infobox
ThermogeninBgeeVentricular system of neuraxis1.00infobox
ThermogeninBgeeplacenta1.00infobox
ThermogeninBgeeventricular zone1.00infobox
ThermogeninBgeeolfactory zone of nasal mucosa1.00infobox
ThermogeninBgeemammary gland1.00infobox
ThermogeninBgeelactiferous gland1.00infobox
ThermogeninBgeeintercostal muscle1.00infobox
ThermogeninBgeeparotid gland1.00infobox
ThermogeninBgeesuperior surface of tongue1.00infobox
ThermogeninBgeetunica adventitia of aorta1.00infobox
ThermogeninBgeetrachea1.00infobox
ThermogeninBgeebrown adipose tissue1.00infobox
ThermogeninBgeesternocleidomastoid muscle1.00infobox
ThermogeninBgeetunica media of zone of aorta1.00infobox
ThermogeninBgeecarotid body1.00infobox
ThermogeninBgeeascending aorta1.00infobox
ThermogeninBioGPSMore reference expression data1.00infobox
ThermogeninChr.Chromosome 4 (human)1.00infobox
ThermogeninChr.Chromosome 8 (mouse)1.00infobox
ThermogeninDatabasesNCBI: entry; OMA: entry1.00infobox
ThermogeninEnd140,568,961 bp1.00infobox
ThermogeninEnd84,025,081 bp1.00infobox
ThermogeninEnsemblENSG000001094241.00infobox

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