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Twinkle protein also known as twinkle mtDNA helicase is a mitochondrial protein that in humans is encoded by the TWNK gene (also known as C10orf2 or PEO1) located in the long arm of chromosome 10 (10q24.31).
The analysis highlights Function, Disease association and Discovery as prominent areas in the source structure around Twinkle (protein).
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
A focused starting point derived from the topic graph, ranked independently of the source article order.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Twinkle (protein) shows recurring relationship patterns in the source. For example, Twinkle (protein) → abdominal wall, autopod region, cumulus cell, epiblast, foot, ganglionic eminence, gastrocnemius muscle, glutes, gonad, interventricular septum, left adrenal cortex, left adrenal gland, mucosa of transverse colon, muscle of thigh, otic vesicle, right adrenal gland, superior cervical ganglion, testicle, ventricular zone Another extracted example is Twinkle (protein) → 5'-3' DNA helicase activity, ATP binding, cellular response to glucose stimulus, DNA helicase activity, DNA replication, DNA unwinding involved in DNA replication, helicase activity, hydrolase activity, mitochondrial DNA replication, mitochondrial matrix, mitochondrial nucleoid, mitochondrial transcription, mitochondrion, mitochondrion organization, nucleotide binding, protease binding, protein hexamerization, protein homooligomerization, single-stranded DNA binding. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
mtdna twinkle protein helicase gene mitochondrial dna human bp chromosome 10 twnk chr band function disease unwinding ataxia known mouse
TTTA extracted 83 structured relationships around Twinkle (protein). Examples in this analysis include Twinkle (protein) → 5.6.2.3 → ↗ and Twinkle (protein) → Aliases → TWNK, ATXN8, IOSCA, MTDPS7, PEO, PEO1, PEOA3, SANDO, SCA8, TWINL, PRLTS5, C10orf2, chromosome 10 open reading frame 2, twinkle mtDNA helicase. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Twinkle (protein) | 5.6.2.3 | ↗ | 1.00 | infobox |
| Twinkle (protein) | Aliases | TWNK, ATXN8, IOSCA, MTDPS7, PEO, PEO1, PEOA3, SANDO, SCA8, TWINL, PRLTS5, C10orf2, chromosome 10 open reading frame 2, twinkle mtDNA helicase | 1.00 | infobox |
| Twinkle (protein) | Band | 10q24.31 | 1.00 | infobox |
| Twinkle (protein) | Band | 19 C3|19 38.19 cM | 1.00 | infobox |
| Twinkle (protein) | Bgee | testicle | 1.00 | infobox |
| Twinkle (protein) | Bgee | gastrocnemius muscle | 1.00 | infobox |
| Twinkle (protein) | Bgee | ventricular zone | 1.00 | infobox |
| Twinkle (protein) | Bgee | gonad | 1.00 | infobox |
| Twinkle (protein) | Bgee | ganglionic eminence | 1.00 | infobox |
| Twinkle (protein) | Bgee | glutes | 1.00 | infobox |
| Twinkle (protein) | Bgee | left adrenal gland | 1.00 | infobox |
| Twinkle (protein) | Bgee | left adrenal cortex | 1.00 | infobox |
| Twinkle (protein) | Bgee | mucosa of transverse colon | 1.00 | infobox |
| Twinkle (protein) | Bgee | right adrenal gland | 1.00 | infobox |
| Twinkle (protein) | Bgee | epiblast | 1.00 | infobox |
| Twinkle (protein) | Bgee | interventricular septum | 1.00 | infobox |
| Twinkle (protein) | Bgee | autopod region | 1.00 | infobox |
| Twinkle (protein) | Bgee | superior cervical ganglion | 1.00 | infobox |
| Twinkle (protein) | Bgee | muscle of thigh | 1.00 | infobox |
| Twinkle (protein) | Bgee | cumulus cell | 1.00 | infobox |
| Twinkle (protein) | Bgee | foot | 1.00 | infobox |
| Twinkle (protein) | Bgee | abdominal wall | 1.00 | infobox |
| Twinkle (protein) | Bgee | otic vesicle | 1.00 | infobox |
| Twinkle (protein) | BioGPS | More reference expression data | 1.00 | infobox |
| Twinkle (protein) | Chr. | Chromosome 10 (human) | 1.00 | infobox |
| Twinkle (protein) | Chr. | Chromosome 19 (mouse) | 1.00 | infobox |
| Twinkle (protein) | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Twinkle (protein) | End | 100,994,403 bp | 1.00 | infobox |
| Twinkle (protein) | End | 45,001,201 bp | 1.00 | infobox |
| Twinkle (protein) | Ensembl | ENSG00000107815 | 1.00 | infobox |
The concept neighborhoods around Twinkle (protein) bring nearby vocabulary together. In this analysis, examples include Twinkle, Mitochondrial and Helicase. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Twinkle (protein), one of the stronger structural bridges in this analysis connects Twinkle (protein) with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Twinkle (protein) to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Disease association & Discovery, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Twinkle (protein) · EN edition · Analysis: TopicsToTalkAbout