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Chromosomal translocation

In genetics, chromosome translocation is a phenomenon that results in unusual rearrangement of chromosomes. This includes "balanced" and "unbalanced" translocation, with three main types: "reciprocal", "nonreciprocal" and "Robertsonian" translocation. Reciprocal translocation is a chromosome abnormality caused by exchange of parts between non-homologous…

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History

Philadelphia chromosomeChronic myelogenous leukemiaQ-bandingG-bandingFISH
5 related topics

Nonreciprocal translocation

GenesNon-homologousDNA replicationCrossing overOncogenes
10 related topics

Robertsonian translocations

Metacentric1314Chromosome 21Down syndrome
8 related topics

Balanced reciprocal translocations

GametesMiscarriagesChildrenGenetic counsellingGenetic testing
6 related topics

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Overview

History

Balanced reciprocal translocations

Unbalanced reciprocal translocations

Nonreciprocal translocation

Robertsonian translocations

Chromosomal structural changes

DNA double-strand breaks with translocations

Role in disease

By chromosome

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Chromosomal translocation

Nodes61
Edges60
Triples32
Avg. degree1.97
Density0.032787
Components1

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Chromosomal translocation

Top relations

related to history · 17
Chromosomal translocation → American, Barbara McClintock's, Chromosomal, DNA, During, FISH, G-banding, In, Janet Rowley, Karl Sax, Philadelphia, Q-banding, Robertson, Robertsonian, The, William, X-ray
related to Role in disease · 10
Chromosomal translocation → An, Cancer, Chromosomal, DNA, Ewing's, Often, Regardless, There, This, Whether
related to External links · 4
Chromosomal translocation → Chromosomal, Media, Wikimedia Commons, Wiktionary-logo-en-v2

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Important terminology

chromosome translocation translocations chromosomes chromosomal genetic result resulting dna may unbalanced robertsonian due genes reciprocal two non-homologous one also balanced

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Ewing's sarcomainstance ofwith additional translation classifications being detected within solid malignancies0.80text
Chromosomal translocationrelated to External linksWiktionary-logo-en-v20.60section
Chromosomal translocationrelated to External linksMedia0.60section
Chromosomal translocationrelated to External linksChromosomal0.60section
Chromosomal translocationrelated to External linksWikimedia Commons0.60section
Chromosomal translocationrelated to historyChromosomal0.60section
Chromosomal translocationrelated to historyIn0.60section
Chromosomal translocationrelated to historyAmerican0.60section
Chromosomal translocationrelated to historyWilliam0.60section
Chromosomal translocationrelated to historyRobertson0.60section
Chromosomal translocationrelated to historyRobertsonian0.60section
Chromosomal translocationrelated to historyKarl Sax0.60section

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