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Tofersen

Tofersen, sold under the brand name Qalsody, is a medication used for the treatment of amyotrophic lateral sclerosis (ALS). Tofersen is an antisense oligonucleotide that targets the production of superoxide dismutase 1, an enzyme whose mutant form is commonly associated with ALS. It is administered as an intrathecal injection.

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Key facts & relationships

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AHFS/Drugs.com
Monograph
ATC code
N07XX22 (WHO)
CAS Number
2088232-70-4
DrugBank
DB14782
Formula
C230H317N72O123P19S15
KEGG
D11811

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Overview

Uses

History

Clinical trials

Advanced semantic analysis

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Map overview Semantic statistics

Tofersen

Nodes25
Edges24
Triples47
Avg. degree1.92
Density0.08
Components1

How this topic connects Entity context

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Tofersen

Top relations

related to Clinical trials · 14
Tofersen → ALS, Approximately, Asian, III, Neuroscience Institute, Sheffield, Sheffield Institute, SITraN, SOD-1, The, Tofersen's, Translational Neuroscience, University, White
related to history · 13
Tofersen → Biogen, Biogen Netherlands, Committee, European Medicines Agency, European Union, Human Use, In February, Ionis Pharmaceuticals, May, Medicinal Products, Qalsody, SOD1, The
Legal status · 3
Tofersen → CA: ℞-only, EU: Rx-only, US: ℞-only
related to Uses · 3
Tofersen → ALS, SOD1, SOD1-ALS
AHFS/Drugs.com · 1
Tofersen → Monograph
ATC code · 1
Tofersen → N07XX22 (WHO)
CAS Number · 1
Tofersen → 2088232-70-4
DrugBank · 1
Tofersen → DB14782
Formula · 1
Tofersen → C230H317N72O123P19S15
KEGG · 1
Tofersen → D11811

Important terminology Word statistics

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Important terminology

als us treatment drug medication qalsody intrathecal superoxide dismutase approved use clinical name eu administration mutation sod1 amyotrophic lateral sclerosis

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
TofersenAHFS/Drugs.comMonograph1.00infobox
TofersenATC codeN07XX22 (WHO)1.00infobox
TofersenCAS Number2088232-70-41.00infobox
TofersenDrugBankDB147821.00infobox
TofersenFormulaC230H317N72O123P19S151.00infobox
TofersenKEGGD118111.00infobox
TofersenLegal statusCA: ℞-only1.00infobox
TofersenLegal statusUS: ℞-only1.00infobox
TofersenLegal statusEU: Rx-only1.00infobox
TofersenLicense dataUS DailyMed: Tofersen1.00infobox
TofersenMedlinePlusa6230241.00infobox
TofersenMolar mass7127.85 g·mol−11.00infobox
TofersenPubChem CID1728734011.00infobox
TofersenRoutes of administrationIntrathecal1.00infobox
TofersenTrade namesQalsody1.00infobox
TofersenUNII2NU6F9601K1.00infobox
Tofersenis aantisense oligonucleotide that targets the production of superoxide dismutase 10.90text

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