Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Dimethyl fumarate

Dimethyl fumarate (DMF) is the methyl ester of fumaric acid. Dimethyl fumarate combined with three other fumaric acid esters (FAEs) is solely licensed in Germany as an oral therapy for psoriasis (brand name Fumaderm). Since 2013, it has been approved by the U.S. Food and Drug Administration (FDA) as a treatment option for adults with relapsing multiple…

History, Applications, Research & Products

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around Dimethyl fumarate. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
ATC code
L04AX07 (WHO)
Boiling point
193 °C (379 °F)
CAS Number
624-49-7 Y
ChEBI
CHEBI:76004 Y
ChEMBL
ChEMBL2107333

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Adverse effects

Pharmacology

Chemistry

History

Consumer products

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Dimethyl fumarate

Nodes47
Edges46
Triples83
Avg. degree1.96
Density0.042553
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Dimethyl fumarate

Top relations

related to Consumer products · 20
Dimethyl fumarate → Argos, BBC Watchdog, British Journal, Chinese, Concentrations, Dermatology, Dimethyl, Finland, In, In Finland, July, Land, Leather, Linkwise, Tapio Rantanen, The, There, United Kingdom, Walmsley, Walmsley Furnishing
related to history · 14
Dimethyl fumarate → Almirall, Based, EMA, European Medicines Agency, Fumaderm, Fumapharm, German, Germany, June, Skilarence, The, The Swiss, This, Walter Schweckendiek
related to Medical uses · 9
Dimethyl fumarate → Cochrane, Fumaderm, In Germany, It, MS, Skilarence, Tecfidera, UK, US
related to COVID-19 · 5
Dimethyl fumarate → COVID-19, In, RECOVERY Trial, The, UK
related to Pharmacology · 5
Dimethyl fumarate → Dimethyl, FDA, MMF, October, Other
Legal status · 3
Dimethyl fumarate → EU: Rx-only, UK: POM (Prescription only), US: ℞-only
related to Synthesis and reactions · 3
Dimethyl fumarate → Dimethyl, Fischer, Several
is a · 2
Dimethyl fumarate → old compound used in industrial chemistry and can be purchased by the ton, precursor of monomethyl fumarate
3D model (JSmol) · 1
Dimethyl fumarate → Interactive image
ATC code · 1
Dimethyl fumarate → L04AX07 (WHO)

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

dimethyl fumarate oral psoriasis treatment products name formulation acid monomethyl multiple sclerosis approved biogen consumer european brand drug relapsing tecfidera

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Dimethyl fumarate3D model (JSmol)Interactive image1.00infobox
Dimethyl fumarateATC codeL04AX07 (WHO)1.00infobox
Dimethyl fumarateBoiling point193 °C (379 °F)1.00infobox
Dimethyl fumarateCAS Number624-49-7 Y1.00infobox
Dimethyl fumarateChEBICHEBI:76004 Y1.00infobox
Dimethyl fumarateChEMBLChEMBL21073331.00infobox
Dimethyl fumarateChemSpider553171 Y1.00infobox
Dimethyl fumarateCompTox Dashboard (EPA)DTXSID40607871.00infobox
Dimethyl fumarateDensity1.37 g/cm3 g/cm31.00infobox
Dimethyl fumarateDrug classImmunomodulator1.00infobox
Dimethyl fumarateDrugBankDB08908 Y1.00infobox
Dimethyl fumarateECHA InfoCard100.009.8631.00infobox
Dimethyl fumarateFormulaC6H8O41.00infobox
Dimethyl fumarateIUPHAR/BPS70451.00infobox
Dimethyl fumarateKEGGD038461.00infobox
Dimethyl fumarateLegal statusUK: POM (Prescription only)1.00infobox
Dimethyl fumarateLegal statusUS: ℞-only1.00infobox
Dimethyl fumarateLegal statusEU: Rx-only1.00infobox
Dimethyl fumarateLicense dataEU EMA: by INN1.00infobox
Dimethyl fumarateMelting point103.5 °C (218.3 °F)1.00infobox
Dimethyl fumarateMolar mass144.126 g·mol−11.00infobox
Dimethyl fumarateOther namesDHF; trans-1,2-Ethylenedicarboxylic acid dimethyl ester; (E)-2-Butenedioic acid dimethyl ester1.00infobox
Dimethyl fumaratePubChem CID6375681.00infobox
Dimethyl fumarateRoutes of administrationOral1.00infobox
Dimethyl fumarateUNIIFO2303MNI21.00infobox
Dimethyl fumarateis aprecursor of monomethyl fumarate0.90text
Dimethyl fumarateis aold compound used in industrial chemistry and can be purchased by the ton0.90text

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.