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Tapasin: Function, Interactions & Overview

TAP-associated glycoprotein, also known as tapasin or TAPBP, is a protein that in humans is encoded by the TAPBP gene.

Language: English [EN]
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Tapasin topic overview

The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around Tapasin.

Related topics
15
Source areas
3
Connected nodes
18
Extracted relationships
113
Concept neighborhoods
12
Bridge connections
18

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 10 topics
Interactions · 3 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
TAPBP, NGS17, TAPA, TPN, TPSN, TAP binding protein (tapasin), TAP binding protein
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3F8U
Band
6p21.32 · 17 B1|17 17.98 cM
Bgee
bone marrow cell · granulocyte · blood · spleen · mucosa of transverse colon
BioGPS
More reference expression data
Chr.
Chromosome 6 (human) · Chromosome 17 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Tapasin connects Entity context

The extracted context around Tapasin shows recurring relationship patterns in the source. For example, Tapasin → ABC-type peptide antigen transporter activity, amide transport, antigen processing and presentation of endogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, endoplasmic reticulum, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment membrane, Golgi membrane, immune response, integral component of lumenal side of endoplasmic reticulum membrane, integral component of membrane, membrane, MHC class I peptide loading complex, MHC class I protein binding, MHC class Ib protein complex assembly, peptide antigen binding, peptide antigen stabilization, peptide transport, phagocytic vesicle membrane Another extracted example is Tapasin → appendix, blood, bone marrow cell, epithelium of colon, granulocyte, Ileal epithelium, lymph node, mesenteric lymph nodes, monocyte, mucosa of transverse colon, pituitary gland, right adrenal gland, right lung, right lung lobe, spleen, stroma of bone marrow, subcutaneous adipose tissue, submandibular gland. Use these groups to spot repeated connection types before inspecting the individual relationships.

Tapasin

Top relations

Gene ontology · 31
Tapasin → ABC-type peptide antigen transporter activity, amide transport, antigen processing and presentation of endogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, antigen processing and presentation of peptide antigen via MHC class I, endoplasmic reticulum, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment membrane, Golgi membrane, immune response, integral component of lumenal side of endoplasmic reticulum membrane, integral component of membrane, membrane, MHC class I peptide loading complex, MHC class I protein binding, MHC class Ib protein complex assembly, peptide antigen binding, peptide antigen stabilization, peptide transport, phagocytic vesicle membrane
Bgee · 18
Tapasin → appendix, blood, bone marrow cell, epithelium of colon, granulocyte, Ileal epithelium, lymph node, mesenteric lymph nodes, monocyte, mucosa of transverse colon, pituitary gland, right adrenal gland, right lung, right lung lobe, spleen, stroma of bone marrow, subcutaneous adipose tissue, submandibular gland
RNA expression pattern · 18
Tapasin → appendix, blood, bone marrow cell, epithelium of colon, granulocyte, Ileal epithelium, lymph node, mesenteric lymph nodes, monocyte, mucosa of transverse colon, pituitary gland, right adrenal gland, right lung, right lung lobe, spleen, stroma of bone marrow, subcutaneous adipose tissue, submandibular gland
related to Function · 15
Tapasin → Alternative, Beta2, C-terminal, ER, ERp57, Following, In, It, KKKAE, MHC, TAP, The, The TAPBP, This, Up
related to External links · 6
Tapasin → Human Tapasin, Medicine Medical Subject Headings, MeSH, National Library, PDB, PDBe-KB
Band · 2
Tapasin → 17 B1|17 17.98 cM, 6p21.32
Chr. · 2
Tapasin → Chromosome 17 (mouse), Chromosome 6 (human)
End · 2
Tapasin → 33,314,254 bp, 34,148,266 bp
Aliases · 1
Tapasin → TAPBP, NGS17, TAPA, TPN, TPSN, TAP binding protein (tapasin), TAP binding protein
Available structures · 1
Tapasin → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3F8U

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

mhc class bp gene human tap chr band chromosome tapbp complex protein also transporter endoplasmic reticulum loading location antigen molecules

Tapasin relationships Subject–Predicate–Object triples

TTTA extracted 113 structured relationships around Tapasin. Examples in this analysis include Tapasin → Aliases → TAPBP, NGS17, TAPA, TPN, TPSN, TAP binding protein (tapasin), TAP binding protein and Tapasin → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3F8U. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
TapasinAliasesTAPBP, NGS17, TAPA, TPN, TPSN, TAP binding protein (tapasin), TAP binding protein1.00infobox
TapasinAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3F8U1.00infobox
TapasinBand6p21.321.00infobox
TapasinBand17 B1|17 17.98 cM1.00infobox
TapasinBgeebone marrow cell1.00infobox
TapasinBgeegranulocyte1.00infobox
TapasinBgeeblood1.00infobox
TapasinBgeespleen1.00infobox
TapasinBgeemucosa of transverse colon1.00infobox
TapasinBgeemonocyte1.00infobox
TapasinBgeeappendix1.00infobox
TapasinBgeelymph node1.00infobox
TapasinBgeeepithelium of colon1.00infobox
TapasinBgeeright adrenal gland1.00infobox
TapasinBgeemesenteric lymph nodes1.00infobox
TapasinBgeeIleal epithelium1.00infobox
TapasinBgeesubcutaneous adipose tissue1.00infobox
TapasinBgeestroma of bone marrow1.00infobox
TapasinBgeeright lung1.00infobox
TapasinBgeeright lung lobe1.00infobox
TapasinBgeepituitary gland1.00infobox
TapasinBgeesubmandibular gland1.00infobox
TapasinBioGPSMore reference expression data1.00infobox
TapasinChr.Chromosome 6 (human)1.00infobox
TapasinChr.Chromosome 17 (mouse)1.00infobox
TapasinDatabasesNCBI: entry; OMA: entry1.00infobox
TapasinEnd33,314,254 bp1.00infobox
TapasinEnd34,148,266 bp1.00infobox
TapasinEnsemblENSG00000231925 ENSG00000236490 ENSG00000206281 ENSG00000206208 ENSG00000112493 n/a1.00infobox
TapasinEntrez68921.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Tapasin bring nearby vocabulary together. In this analysis, examples include Class, Mhc and Tap. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Tapasin
    • Class
    • Mhc
    • Tap
    • Complex
    • Associated
    • Endoplasmic
    • Molecule
    • Protein
    • Reticulum
    • Tapbp
    • Transporter
    • Loading
  • tapasin
    • Class
    • Mhc
    • Tap
    • Complex
    • Associated
    • Endoplasmic
    • Molecule
    • Protein
    • Reticulum
    • Tapbp
    • Transporter
    • Loading
  • protein
    • Tapbp
    • Binding
    • Function
    • Search
    • Location
    • Bp
    • Chr
    • Chromosome
    • External
    • Human
    • Tap
    • Antigen
  • gene
    • Chromosome
    • Location
    • Protein
    • Tapbp
    • Bp
    • Chr
    • Human
    • Binding
    • End
    • Function
    • Glycoprotein
    • Humans
  • glycoprotein
    • Protein
    • Tapbp
    • Gene
    • Antigen
    • Binding
    • End
    • Function
    • Humans
    • Known
    • Membrane
    • Mouse
    • Processing
  • class i
    • Mhc
    • Loading
    • Molecules
    • Tapasin
    • Tap
    • Interaction
    • Molecule
    • Peptide
    • Complex
    • Endoplasmic
    • Reticulum
    • Transporter
  • antigen
    • Processing
    • Associated
    • Transporter
    • Binding
    • End
    • Function
    • Glycoprotein
    • Membrane
    • Mouse
    • Search
    • Tap
    • Endoplasmic
  • function
    • Binding
    • Search
    • Location
    • Protein
    • Tapbp
    • Bp
    • Chr
    • Chromosome
    • Gene
    • Human
    • Antigen
    • End

Connections between topic areas Semantic bridges

For Tapasin, one of the stronger structural bridges in this analysis connects Tapasin with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
TapasinFunction · splits 8 ⟂ 11
TapasinInteractions · splits 15 ⟂ 4
TapasinOverview · splits 16 ⟂ 3

Map overview Semantic statistics

Tapasin

Nodes19
Edges18
Triples113
Avg. degree1.89
Density0.105263
Components1

Source & methodology

TTTA analyzes the structure around Tapasin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Tapasin · EN edition · Analysis: TopicsToTalkAbout

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