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Structural genomics

Structural genomics seeks to describe the 3-dimensional structure of every protein encoded by a given genome. This genome-based approach allows for a high-throughput method of structure determination by a combination of experimental and modeling approaches. The principal difference between structural genomics and traditional structural prediction is that…

Products, Examples of structural genomics & Methods

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Overview

Goals

Methods

Examples of structural genomics

Protein structure databases and classifications

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Map overview Semantic statistics

Structural genomics

Nodes35
Edges34
Triples35
Avg. degree1.94
Density0.057143
Components1

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Structural genomics

Top relations

related to Thermotoga maritima proteome · 13
Structural genomics → Among, Escherichia, JCSG, Joint Center, Lesley, One, ORFs, Protein Structure Initiative, PSI, Thermotoga, These, TM0449, X-ray
related to Goals · 10
Structural genomics → Experimental, Furthermore, Health, National Institutes, One, Protein, PSI, The Protein Structure Initiative, This, Thus
related to Mycobacterium tuberculosis proteome · 6
Structural genomics → Mycobacterium, So, Studies, TB Structural Genomics Consortium, The, X-ray
has method · 2
Structural genomics → Structural, The

Important terminology Word statistics

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Important terminology

protein structural genomics structure structures proteins determination approach genome modeling sequences sequence one every function novel unknown encoded known experimental

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
clonesinstance ofas well as to reagents0.80text
proteininstance ofas well as to reagents0.80text
ab initio modeling may be better able to identify novel protein folds than the experimental approaches because they are not limited by experimental constraints.Protein function depends on 3-D structureinstance ofmodeling-based approach0.80text
these 3-D structures are more highly conserved than sequencesinstance ofmodeling-based approach0.80text
Structural genomicshas methodStructural0.60section
Structural genomicshas methodThe0.60section
Structural genomicsrelated to GoalsOne0.60section
Structural genomicsrelated to GoalsExperimental0.60section
Structural genomicsrelated to GoalsProtein0.60section
Structural genomicsrelated to GoalsThus0.60section
Structural genomicsrelated to GoalsThis0.60section
Structural genomicsrelated to GoalsFurthermore0.60section

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