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Stephen aldehyde synthesis

Stephen aldehyde synthesis, a named reaction in chemistry, was invented by Henry Stephen (OBE/MBE). This reaction involves the preparation of aldehydes (R-CHO) from nitriles (R-CN) using tin(II) chloride (SnCl2), hydrochloric acid (HCl) and quenching the resulting iminium salt (+Cl−) with water (H2O). During the synthesis, ammonium chloride is also…

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Stephen aldehyde synthesis

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reaction chloride salt tin nitriles resulting synthesis amide also aldehyde named type iminium electron using ii acid addition mechanism sonn-müller

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