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Sodium- and chloride-dependent glycine transporter 1: Selective inhibitors, Pathological mutations & Overview

Sodium- and chloride-dependent glycine transporter 1, also known as glycine transporter 1, is a protein that in humans is encoded by the SLC6A9 gene which is promising therapeutic target for treatment of diabetes and obesity.

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Sodium- and chloride-dependent glycine transporter 1 topic overview

The analysis highlights Selective inhibitors, Pathological mutations and Overview as prominent areas in the source structure around Sodium- and chloride-dependent glycine transporter 1.

Related topics
14
Source areas
3
Connected nodes
17
Extracted relationships
86
Related term clusters
9
Bridge connections
17

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Selective inhibitors · 10 topics
Overview · 2 topics
Pathological mutations · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SLC6A9, GLYT1, Glycine transporter 1, solute carrier family 6 member 9, GCENSG
Band
1p34.1 · 4 D1|4 53.62 cM
Bgee
C1 segment · skin of leg · skin of abdomen · right adrenal gland · stromal cell of endometrium
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 4 (mouse)
Databases
NCBI: entry; OMA: entry

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Sodium- and chloride-dependent glycine transporter 1

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Selective inhibitors

Pathological mutations

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Sodium- and chloride-dependent glycine transporter 1 connects Entity context

The extracted context around Sodium- and chloride-dependent glycine transporter 1 shows recurring relationship patterns in the source. For example, Sodium- and chloride-dependent glycine transporter 1 → amino acid transmembrane transport, amino acid transport, amino acid:sodium symporter activity, asymmetric synapse, glycine secretion, neurotransmission, glycine transmembrane transporter activity, glycine transport, glycine:sodium symporter activity, hippocampal mossy fiber to CA3 synapse, integral component of membrane, integral component of plasma membrane, integral component of postsynaptic membrane, integral component of presynaptic membrane, integral component of synaptic vesicle membrane, membrane, neurotransmitter transport, neurotransmitter:sodium symporter activity, organic acid transmembrane transport, parallel fiber to Purkinje cell synapse, plasma membrane Another extracted example is Sodium- and chloride-dependent glycine transporter 1 → C1 segment, deep cerebellar nuclei, dorsal tegmental nucleus, fetal liver hematopoietic progenitor cell, left adrenal cortex, left adrenal gland, lumbar subsegment of spinal cord, medulla oblongata, mucosa of esophagus, mucosa of transverse colon, neural layer of retina, primary oocyte, retinal pigment epithelium, right adrenal cortex, right adrenal gland, secondary oocyte, skin of abdomen, skin of leg, stromal cell of endometrium, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

Sodium- and chloride-dependent glycine transporter 1

Top relations

Gene ontology · 26
Sodium- and chloride-dependent glycine transporter 1 → amino acid transmembrane transport, amino acid transport, amino acid:sodium symporter activity, asymmetric synapse, glycine secretion, neurotransmission, glycine transmembrane transporter activity, glycine transport, glycine:sodium symporter activity, hippocampal mossy fiber to CA3 synapse, integral component of membrane, integral component of plasma membrane, integral component of postsynaptic membrane, integral component of presynaptic membrane, integral component of synaptic vesicle membrane, membrane, neurotransmitter transport, neurotransmitter:sodium symporter activity, organic acid transmembrane transport, parallel fiber to Purkinje cell synapse, plasma membrane
Bgee · 20
Sodium- and chloride-dependent glycine transporter 1 → C1 segment, deep cerebellar nuclei, dorsal tegmental nucleus, fetal liver hematopoietic progenitor cell, left adrenal cortex, left adrenal gland, lumbar subsegment of spinal cord, medulla oblongata, mucosa of esophagus, mucosa of transverse colon, neural layer of retina, primary oocyte, retinal pigment epithelium, right adrenal cortex, right adrenal gland, secondary oocyte, skin of abdomen, skin of leg, stromal cell of endometrium, zygote
RNA expression pattern · 20
Sodium- and chloride-dependent glycine transporter 1 → C1 segment, deep cerebellar nuclei, dorsal tegmental nucleus, fetal liver hematopoietic progenitor cell, left adrenal cortex, left adrenal gland, lumbar subsegment of spinal cord, medulla oblongata, mucosa of esophagus, mucosa of transverse colon, neural layer of retina, primary oocyte, retinal pigment epithelium, right adrenal cortex, right adrenal gland, secondary oocyte, skin of abdomen, skin of leg, stromal cell of endometrium, zygote
Band · 2
Sodium- and chloride-dependent glycine transporter 1 → 1p34.1, 4 D1|4 53.62 cM
Chr. · 2
Sodium- and chloride-dependent glycine transporter 1 → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
Sodium- and chloride-dependent glycine transporter 1 → 117,732,395 bp, 44,031,467 bp
Aliases · 1
Sodium- and chloride-dependent glycine transporter 1 → SLC6A9, GLYT1, Glycine transporter 1, solute carrier family 6 member 9, GCENSG
BioGPS · 1
Sodium- and chloride-dependent glycine transporter 1 → More reference expression data
Databases · 1
Sodium- and chloride-dependent glycine transporter 1 → NCBI: entry; OMA: entry
Ensembl · 1
Sodium- and chloride-dependent glycine transporter 1 → ENSG00000196517

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp glycine gene chr human band chromosome slc6a9 transporter also location treatment protein mouse glyt1 omim known 031 467 end

Sodium- and chloride-dependent glycine transporter 1 relationships Subject–Predicate–Object triples

TTTA extracted 86 structured relationships around Sodium- and chloride-dependent glycine transporter 1. Examples in this analysis include Sodium- and chloride-dependent glycine transporter 1 → Aliases → SLC6A9, GLYT1, Glycine transporter 1, solute carrier family 6 member 9, GCENSG and Sodium- and chloride-dependent glycine transporter 1 → Band → 1p34.1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Sodium- and chloride-dependent glycine transporter 1AliasesSLC6A9, GLYT1, Glycine transporter 1, solute carrier family 6 member 9, GCENSG1.00infobox
Sodium- and chloride-dependent glycine transporter 1Band1p34.11.00infobox
Sodium- and chloride-dependent glycine transporter 1Band4 D1|4 53.62 cM1.00infobox
Sodium- and chloride-dependent glycine transporter 1BgeeC1 segment1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeeskin of leg1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeeskin of abdomen1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeeright adrenal gland1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeestromal cell of endometrium1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeeleft adrenal gland1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeeright adrenal cortex1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeeleft adrenal cortex1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeemucosa of transverse colon1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeemucosa of esophagus1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeeneural layer of retina1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeesecondary oocyte1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeeretinal pigment epithelium1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeefetal liver hematopoietic progenitor cell1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeedeep cerebellar nuclei1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeeprimary oocyte1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeezygote1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeelumbar subsegment of spinal cord1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeemedulla oblongata1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeedorsal tegmental nucleus1.00infobox
Sodium- and chloride-dependent glycine transporter 1BioGPSMore reference expression data1.00infobox
Sodium- and chloride-dependent glycine transporter 1Chr.Chromosome 1 (human)1.00infobox
Sodium- and chloride-dependent glycine transporter 1Chr.Chromosome 4 (mouse)1.00infobox
Sodium- and chloride-dependent glycine transporter 1DatabasesNCBI: entry; OMA: entry1.00infobox
Sodium- and chloride-dependent glycine transporter 1End44,031,467 bp1.00infobox
Sodium- and chloride-dependent glycine transporter 1End117,732,395 bp1.00infobox
Sodium- and chloride-dependent glycine transporter 1EnsemblENSG000001965171.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around Sodium- and chloride-dependent glycine transporter 1 bring nearby vocabulary together. In this analysis, examples include Sodium-, Glyt1 and Cognitive. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Sodium- and chloride-dependent glycine transporter 1
    • Sodium-
    • Glyt1
    • Cognitive
    • Known
    • Mutations
    • Omim
    • Protein
    • Schizophrenia
    • Location
    • Also
    • Chromosome
    • Human
  • sodium- and chloride-dependent glycine transporter 1
    • Sodium-
    • Gene
    • Also
    • Glyt1
    • Slc6a9
    • Transporter
    • Treatment
    • Cognitive
    • Known
    • Location
    • Mutations
    • Omim
  • gene
    • Glycine
    • Glyt1
    • Location
    • Slc6a9
    • Transporter
    • Treatment
    • Chromosome
    • Human
    • Bp
    • Chr
    • Cognitive
    • D1
  • glycine
    • Gene
    • Also
    • Glyt1
    • Slc6a9
    • Transporter
    • Treatment
    • Cognitive
    • Known
    • Mutations
    • Omim
    • Protein
    • Schizophrenia
  • glycine encephalopathy with normal serum glycine
    • Gene
    • Also
    • Glyt1
    • Slc6a9
    • Transporter
    • Treatment
    • Cognitive
    • Known
    • Mutations
    • Omim
    • Protein
    • Schizophrenia
  • protein
    • Slc6a9
    • Transporter
    • Treatment
    • Function
    • Sodium-
    • Synaptic
    • Gene
    • Cognitive
    • D1
    • End
    • Mouse
    • Neurotransmitter
  • pathological mutations
    • Omim
    • Glyt1
    • Carrier
    • Cognitive
    • Family
    • Schizophrenia
    • Solute
    • Trials
    • Location
    • Slc6a9
    • Transporter
    • Treatment
  • schizophrenia
    • Treatment
    • Synaptic
    • Sodium
    • Symporter
    • Trials
    • Slc6a9
    • Transporter

Connections between topic areas Semantic bridges

For Sodium- and chloride-dependent glycine transporter 1, one of the stronger structural bridges in this analysis connects Sodium- and chloride-dependent glycine transporter 1 with Selective inhibitors. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Sodium- and chloride-dependent glycine transporter 1 — Selective inhibitors · splits 7 ⟂ 11
Sodium- and chloride-dependent glycine transporter 1 — Overview · splits 15 ⟂ 3
Sodium- and chloride-dependent glycine transporter 1 — Pathological mutations · splits 15 ⟂ 3

Map overview Semantic statistics

Sodium- and chloride-dependent glycine transporter 1

Nodes18
Edges17
Triples86
Avg. degree1.89
Density0.111111
Components1

Source & methodology

TTTA analyzes the structure around Sodium- and chloride-dependent glycine transporter 1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Selective inhibitors, Pathological mutations & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Sodium- and chloride-dependent glycine transporter 1 · EN edition · Analysis: TopicsToTalkAbout

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