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Sodium- and chloride-dependent glycine transporter 1

Sodium- and chloride-dependent glycine transporter 1, also known as glycine transporter 1, is a protein that in humans is encoded by the SLC6A9 gene which is promising therapeutic target for treatment of diabetes and obesity.

Selective inhibitors, Pathological mutations & Overview

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Selective inhibitors

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Pathological mutations

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Overview

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Key facts & relationships

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Aliases
SLC6A9, GLYT1, Glycine transporter 1, solute carrier family 6 member 9, GCENSG
Band
1p34.1 · 4 D1|4 53.62 cM
Bgee
C1 segment · skin of leg · skin of abdomen · right adrenal gland · stromal cell of endometrium
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 4 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

Selective inhibitors

Pathological mutations

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Map overview Semantic statistics

Sodium- and chloride-dependent glycine transporter 1

Nodes18
Edges17
Triples86
Avg. degree1.89
Density0.111111
Components1

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Sodium- and chloride-dependent glycine transporter 1

Top relations

Gene ontology · 26
Sodium- and chloride-dependent glycine transporter 1 → amino acid transmembrane transport, amino acid transport, amino acid:sodium symporter activity, asymmetric synapse, glycine secretion, neurotransmission, glycine transmembrane transporter activity, glycine transport, glycine:sodium symporter activity, hippocampal mossy fiber to CA3 synapse, integral component of membrane, integral component of plasma membrane, integral component of postsynaptic membrane, integral component of presynaptic membrane, integral component of synaptic vesicle membrane, membrane, neurotransmitter transport, neurotransmitter:sodium symporter activity, organic acid transmembrane transport, parallel fiber to Purkinje cell synapse, plasma membrane
Bgee · 20
Sodium- and chloride-dependent glycine transporter 1 → C1 segment, deep cerebellar nuclei, dorsal tegmental nucleus, fetal liver hematopoietic progenitor cell, left adrenal cortex, left adrenal gland, lumbar subsegment of spinal cord, medulla oblongata, mucosa of esophagus, mucosa of transverse colon, neural layer of retina, primary oocyte, retinal pigment epithelium, right adrenal cortex, right adrenal gland, secondary oocyte, skin of abdomen, skin of leg, stromal cell of endometrium, zygote
RNA expression pattern · 20
Sodium- and chloride-dependent glycine transporter 1 → C1 segment, deep cerebellar nuclei, dorsal tegmental nucleus, fetal liver hematopoietic progenitor cell, left adrenal cortex, left adrenal gland, lumbar subsegment of spinal cord, medulla oblongata, mucosa of esophagus, mucosa of transverse colon, neural layer of retina, primary oocyte, retinal pigment epithelium, right adrenal cortex, right adrenal gland, secondary oocyte, skin of abdomen, skin of leg, stromal cell of endometrium, zygote
Band · 2
Sodium- and chloride-dependent glycine transporter 1 → 1p34.1, 4 D1|4 53.62 cM
Chr. · 2
Sodium- and chloride-dependent glycine transporter 1 → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
Sodium- and chloride-dependent glycine transporter 1 → 117,732,395 bp, 44,031,467 bp
Aliases · 1
Sodium- and chloride-dependent glycine transporter 1 → SLC6A9, GLYT1, Glycine transporter 1, solute carrier family 6 member 9, GCENSG
BioGPS · 1
Sodium- and chloride-dependent glycine transporter 1 → More reference expression data
Databases · 1
Sodium- and chloride-dependent glycine transporter 1 → NCBI: entry; OMA: entry
Ensembl · 1
Sodium- and chloride-dependent glycine transporter 1 → ENSG00000196517

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Important terminology

bp glycine gene chr human band chromosome slc6a9 transporter also location treatment protein mouse glyt1 omim known 031 467 end

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Sodium- and chloride-dependent glycine transporter 1AliasesSLC6A9, GLYT1, Glycine transporter 1, solute carrier family 6 member 9, GCENSG1.00infobox
Sodium- and chloride-dependent glycine transporter 1Band1p34.11.00infobox
Sodium- and chloride-dependent glycine transporter 1Band4 D1|4 53.62 cM1.00infobox
Sodium- and chloride-dependent glycine transporter 1BgeeC1 segment1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeeskin of leg1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeeskin of abdomen1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeeright adrenal gland1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeestromal cell of endometrium1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeeleft adrenal gland1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeeright adrenal cortex1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeeleft adrenal cortex1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeemucosa of transverse colon1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeemucosa of esophagus1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeeneural layer of retina1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeesecondary oocyte1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeeretinal pigment epithelium1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeefetal liver hematopoietic progenitor cell1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeedeep cerebellar nuclei1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeeprimary oocyte1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeezygote1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeelumbar subsegment of spinal cord1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeemedulla oblongata1.00infobox
Sodium- and chloride-dependent glycine transporter 1Bgeedorsal tegmental nucleus1.00infobox
Sodium- and chloride-dependent glycine transporter 1BioGPSMore reference expression data1.00infobox
Sodium- and chloride-dependent glycine transporter 1Chr.Chromosome 1 (human)1.00infobox
Sodium- and chloride-dependent glycine transporter 1Chr.Chromosome 4 (mouse)1.00infobox
Sodium- and chloride-dependent glycine transporter 1DatabasesNCBI: entry; OMA: entry1.00infobox
Sodium- and chloride-dependent glycine transporter 1End44,031,467 bp1.00infobox
Sodium- and chloride-dependent glycine transporter 1End117,732,395 bp1.00infobox
Sodium- and chloride-dependent glycine transporter 1EnsemblENSG000001965171.00infobox

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