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Sigma factor

A sigma factor (σ factor or specificity factor) is a protein needed for initiation of transcription in bacteria. It is a bacterial transcription initiation factor that enables specific binding of RNA polymerase (RNAP) to gene promoters. They are also found in plant chloroplasts as a part of the bacteria-like plastid-encoded polymerase (PEP). It is…

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Specialized sigma factors

Σ70(RpoD)Consensus sequencesΣ19 (FecI)Σ24 (RpoE)Σ28 (RpoF/FliA)
13 related topics

Overview

TranscriptionBacteriaBacterial transcriptionRNA polymerasePromoters
14 related topics

Structure

InterProPribnow box
2 related topics

Retention during transcription elongation

Holoenzyme
1 related topics

Key facts & relationships

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AlphaFold
IPR007127 · PF03979
Available protein structures:
IPR007127 · PF03979
InterPro
IPR007127
PDB
IPR007127 PF03979 (ECOD; PDBsum)
Pfam
PF03979
Symbol
Sigma70_r1_1

Topics to explore

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Overview

Specialized sigma factors

Structure

Retention during transcription elongation

Sigma cycle

Advanced semantic analysis

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Map overview Semantic statistics

Sigma factor

Nodes37
Edges36
Triples44
Avg. degree1.95
Density0.054054
Components1

How this topic connects Entity context

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Sigma factor

Top relations

related to Retention during transcription elongation · 9
Sigma factor → All, Finally, However, Indeed, It, RNA, The, This, Thus
related to Genes with dual sigma factor preference · 7
Sigma factor → In, RegulonDB, RNAP, Studies, The, This, While
related to Sigma factor competition · 6
Sigma factor → Consequently, However, Interestingly, Meanwhile, RNAPs, The
related to Structure · 6
Sigma factor → By, For, InterPro, IPR000943, The, They
related to Sigma cycle · 5
Sigma factor → However, Instead, It, Therefore, Thus
related to Specialized sigma factors · 3
Sigma factor → Different, Sigma, These
AlphaFold · 2
Sigma factor → IPR007127, PF03979
Available protein structures: · 2
Sigma factor → IPR007127, PF03979
InterPro · 1
Sigma factor → IPR007127
PDB · 1
Sigma factor → IPR007127 PF03979 (ECOD; PDBsum)

Important terminology Word statistics

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Important terminology

sigma factor factors transcription polymerase rna initiation holoenzyme elongation promoter coli genes also promoters core σ70 complex rnap gene called

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Sigma factorAlphaFoldIPR0071271.00infobox
Sigma factorAlphaFoldPF039791.00infobox
Sigma factorAvailable protein structures:IPR0071271.00infobox
Sigma factorAvailable protein structures:PF039791.00infobox
Sigma factorInterProIPR0071271.00infobox
Sigma factorPDBIPR007127 PF03979 (ECOD; PDBsum)1.00infobox
Sigma factorPfamPF039791.00infobox
Sigma factorSymbolSigma70_r1_11.00infobox
Sigma factorrelated to Genes with dual sigma factor preferenceWhile0.60section
Sigma factorrelated to Genes with dual sigma factor preferenceRNAP0.60section
Sigma factorrelated to Genes with dual sigma factor preferenceRegulonDB0.60section
Sigma factorrelated to Genes with dual sigma factor preferenceThe0.60section

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