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SFRP2

Secreted frizzled-related protein 2 is a protein that in humans is encoded by the SFRP2 gene. This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence…

Cancer & Overview

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Aliases
SFRP2, FRP-2, SARP1, SDF-5, secreted frizzled related protein 2
Band
4q31.3 · 3 E3|3 37.37 cM
Bgee
skin of arm · parietal pleura · gallbladder · vena cava · skin of thigh
BioGPS
More reference expression data
Chr.
Chromosome 4 (human) · Chromosome 3 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

Cancer

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Map overview Semantic statistics

SFRP2

Nodes13
Edges12
Triples145
Avg. degree1.85
Density0.153846
Components1

How this topic connects Entity context

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SFRP2

Top relations

Gene ontology · 83
SFRP2 → anterior/posterior pattern specification, apoptotic process, bone morphogenesis, branching involved in blood vessel morphogenesis, canonical Wnt signaling pathway, cardiac left ventricle morphogenesis, cartilage development, cell differentiation, cell-cell signaling, cellular response to extracellular stimulus, cellular response to X-ray, chondrocyte development, collagen fibril organization, collagen-containing extracellular matrix, convergent extension involved in axis elongation, development of primary male sexual characteristics, digestive tract morphogenesis, embryonic digit morphogenesis, endopeptidase activator activity, enzyme activator activity
Bgee · 20
SFRP2 → aortic valve, ascending aorta, calvaria, condyle, endocardial cushion, external carotid artery, fossa, gallbladder, hand, internal carotid artery, lactiferous duct, parietal pleura, pericardium, renal corpuscle, skin of arm, skin of hip, skin of thigh, trachea, vena cava, ventricular zone
RNA expression pattern · 20
SFRP2 → aortic valve, ascending aorta, calvaria, condyle, endocardial cushion, external carotid artery, fossa, gallbladder, hand, internal carotid artery, lactiferous duct, parietal pleura, pericardium, renal corpuscle, skin of arm, skin of hip, skin of thigh, trachea, vena cava, ventricular zone
Band · 2
SFRP2 → 3 E3|3 37.37 cM, 4q31.3
Chr. · 2
SFRP2 → Chromosome 3 (mouse), Chromosome 4 (human)
End · 2
SFRP2 → 153,789,083 bp, 83,681,623 bp
related to Cancer · 2
SFRP2 → For, Human
Aliases · 1
SFRP2 → SFRP2, FRP-2, SARP1, SDF-5, secreted frizzled related protein 2
BioGPS · 1
SFRP2 → More reference expression data
Databases · 1
SFRP2 → NCBI: entry; OMA: entry

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Important terminology

gene bp human chr band chromosome mouse protein location frizzled cancer secreted domain wnt signaling via potential marker may external

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
SFRP2AliasesSFRP2, FRP-2, SARP1, SDF-5, secreted frizzled related protein 21.00infobox
SFRP2Band4q31.31.00infobox
SFRP2Band3 E3|3 37.37 cM1.00infobox
SFRP2Bgeeskin of arm1.00infobox
SFRP2Bgeeparietal pleura1.00infobox
SFRP2Bgeegallbladder1.00infobox
SFRP2Bgeevena cava1.00infobox
SFRP2Bgeeskin of thigh1.00infobox
SFRP2Bgeetrachea1.00infobox
SFRP2Bgeeskin of hip1.00infobox
SFRP2Bgeelactiferous duct1.00infobox
SFRP2Bgeepericardium1.00infobox
SFRP2Bgeeventricular zone1.00infobox
SFRP2Bgeeascending aorta1.00infobox
SFRP2Bgeeaortic valve1.00infobox
SFRP2Bgeecalvaria1.00infobox
SFRP2Bgeehand1.00infobox
SFRP2Bgeeendocardial cushion1.00infobox
SFRP2Bgeerenal corpuscle1.00infobox
SFRP2Bgeecondyle1.00infobox
SFRP2Bgeefossa1.00infobox
SFRP2Bgeeinternal carotid artery1.00infobox
SFRP2Bgeeexternal carotid artery1.00infobox
SFRP2BioGPSMore reference expression data1.00infobox
SFRP2Chr.Chromosome 4 (human)1.00infobox
SFRP2Chr.Chromosome 3 (mouse)1.00infobox
SFRP2DatabasesNCBI: entry; OMA: entry1.00infobox
SFRP2End153,789,083 bp1.00infobox
SFRP2End83,681,623 bp1.00infobox
SFRP2EnsemblENSG000001454231.00infobox

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