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SCO2

SCO2 cytochrome c oxidase assembly (also known as SCO2 homolog, mitochondrial and SCO cytochrome oxidase deficient homolog 2) is a protein that in humans is encoded by the SCO2 gene. The encoded protein is one of the cytochrome c oxidase (COX)(Complex IV) assembly factors. Human COX is a multimeric protein complex that requires several assembly factors.…

Clinical significance, Function & Structure

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Aliases
SCO2, CEMCOX1, MYP6, SCO1L, SCO2 cytochrome c oxidase assembly protein, cytochrome c oxidase assembly protein, PD-ECGF, TP, Gliostatin, TYMP, ECGF1, TdRPase, SCO cytochrome c ox…
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2RLI
Band
22q13.33 · 15|15 E3
Bgee
right uterine tube · granulocyte · mucosa of transverse colon · monocyte · gingival epithelium
BioGPS
n/a
Chr.
Chromosome 22 (human) · Chromosome 15 (mouse)

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Clinical significance

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Map overview Semantic statistics

SCO2

Nodes65
Edges64
Triples119
Avg. degree1.97
Density0.030769
Components1

How this topic connects Entity context

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SCO2

Top relations

Bgee · 20
SCO2 → blastocyst, colon, duodenum, embryo, epithelium of bronchus, gingival epithelium, gonad, granulocyte, jejunum, monocyte, morula, mucosa of transverse colon, muscle of thigh, palpebral conjunctiva, periodontal fiber, proximal tubule, right kidney, right lobe of liver, right uterine tube, yolk sac
RNA expression pattern · 20
SCO2 → blastocyst, colon, duodenum, embryo, epithelium of bronchus, gingival epithelium, gonad, granulocyte, jejunum, monocyte, morula, mucosa of transverse colon, muscle of thigh, palpebral conjunctiva, periodontal fiber, proximal tubule, right kidney, right lobe of liver, right uterine tube, yolk sac
Gene ontology · 17
SCO2 → cell redox homeostasis, cellular copper ion homeostasis, copper ion binding, copper ion transport, eye development, integral component of membrane, integral component of mitochondrial inner membrane, membrane, metal ion binding, mitochondrial cytochrome c oxidase assembly, mitochondrial inner membrane, mitochondrial matrix, mitochondrion, myofibril, protein binding, protein-disulfide reductase activity, respiratory chain complex IV assembly
related to Clinical significance · 15
SCO2 → Cardioencephalomyopathy, CEMCOX1, Clinical, COX, E140K, G1541A, Lastly, Leigh, LS, Mutations, Myopia, MYP6, Other, Q53X, SMA
related to Function · 9
SCO2 → Complex IV, COX, Cu, II, In, Mammalian, SCO1, The, The SCO2
related to Interactions · 7
SCO2 → COA6, COX16, COX20, COX20-dependent, In, SCO1, THEM177
related to Structure · 6
SCO2 → Complex IV, COX, Mammalian, N-terminal, The, The SCO2
Band · 2
SCO2 → 15|15 E3, 22q13.33
Chr. · 2
SCO2 → Chromosome 15 (mouse), Chromosome 22 (human)
End · 2
SCO2 → 50,526,461 bp, 89,258,049 bp

Important terminology Word statistics

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Important terminology

cytochrome protein oxidase gene human cox assembly complex bp mitochondrial iv chr band subunit chromosome 22 ii encoded location copper

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
SCO2AliasesSCO2, CEMCOX1, MYP6, SCO1L, SCO2 cytochrome c oxidase assembly protein, cytochrome c oxidase assembly protein, PD-ECGF, TP, Gliostatin, TYMP, ECGF1, TdRPase, SCO cytochrome c ox…1.00infobox
SCO2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2RLI1.00infobox
SCO2Band22q13.331.00infobox
SCO2Band15|15 E31.00infobox
SCO2Bgeeright uterine tube1.00infobox
SCO2Bgeegranulocyte1.00infobox
SCO2Bgeemucosa of transverse colon1.00infobox
SCO2Bgeemonocyte1.00infobox
SCO2Bgeegingival epithelium1.00infobox
SCO2Bgeegonad1.00infobox
SCO2Bgeepalpebral conjunctiva1.00infobox
SCO2Bgeeperiodontal fiber1.00infobox
SCO2Bgeeright lobe of liver1.00infobox
SCO2Bgeeepithelium of bronchus1.00infobox
SCO2Bgeeyolk sac1.00infobox
SCO2Bgeeblastocyst1.00infobox
SCO2Bgeeembryo1.00infobox
SCO2Bgeeduodenum1.00infobox
SCO2Bgeecolon1.00infobox
SCO2Bgeeproximal tubule1.00infobox
SCO2Bgeeright kidney1.00infobox
SCO2Bgeemuscle of thigh1.00infobox
SCO2Bgeejejunum1.00infobox
SCO2Bgeemorula1.00infobox
SCO2BioGPSn/a1.00infobox
SCO2Chr.Chromosome 22 (human)1.00infobox
SCO2Chr.Chromosome 15 (mouse)1.00infobox
SCO2DatabasesNCBI: entry; OMA: entry1.00infobox
SCO2End50,526,461 bp1.00infobox
SCO2End89,258,049 bp1.00infobox

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