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Stearoyl-CoA desaturase (Δ-9-desaturase or SCD-1) is an endoplasmic reticulum enzyme that catalyzes the rate-limiting step in the formation of monounsaturated fatty acids (MUFAs), specifically oleate and palmitoleate from stearoyl-CoA and palmitoyl-CoA. Oleate and palmitoleate are major components of membrane phospholipids, cholesterol esters and…
Role in human disease, Function & Overview
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enzyme fatty scd-1 acid stearoyl-coa desaturase oxygen acids double synthesis bond scd liver scd1 monounsaturated two also oleate expression membrane
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Stearoyl-CoA 9-desaturase | Alt. names | Delta9-desaturase, acyl-CoA desaturase, fatty acid desaturase, and stearoyl-CoA, hydrogen-donor:oxygen oxidoreductase | 1.00 | infobox |
| Stearoyl-CoA 9-desaturase | BRENDA | enzyme data | 1.00 | infobox |
| Stearoyl-CoA 9-desaturase | CAS no. | 9014-34-0[permanent dead link] | 1.00 | infobox |
| Stearoyl-CoA 9-desaturase | EC no. | 1.14.19.1 | 1.00 | infobox |
| Stearoyl-CoA 9-desaturase | ExPASy | NiceZyme view | 1.00 | infobox |
| Stearoyl-CoA 9-desaturase | Gene Ontology | AmiGO / QuickGO | 1.00 | infobox |
| Stearoyl-CoA 9-desaturase | KEGG | enzyme entry | 1.00 | infobox |
| Stearoyl-CoA 9-desaturase | MetaCyc | metabolic pathway | 1.00 | infobox |
| Stearoyl-CoA 9-desaturase | NCBI | proteins | 1.00 | infobox |
| Stearoyl-CoA 9-desaturase | PDB structures | RCSB PDB PDBe PDBsum | 1.00 | infobox |
| Stearoyl-CoA 9-desaturase | PMC | articles | 1.00 | infobox |
| Stearoyl-CoA 9-desaturase | PubMed | articles | 1.00 | infobox |
| Stearoyl-CoA 9-desaturase | Rhea | reactions | 1.00 | infobox |
| Stearoyl-CoA 9-desaturase | Search | SearchPMCarticlesPubMedarticlesNCBIproteins | 1.00 | infobox |
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