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RPGRIP1: Interactions & Overview

X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 is a protein in the ciliary transition zone that in humans is encoded by the RPGRIP1 gene. RPGRIP1 is a multi-domain protein containing a coiled-coil domain at the N-terminus, two C2 domains and a C-terminal RPGR-interacting domain (RID). Defects in the gene result in the Leber…

Language: English [EN]
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RPGRIP1 topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around RPGRIP1.

Related topics
14
Source areas
2
Connected nodes
16
Extracted relationships
22
Concept neighborhoods
14
Bridge connections
16

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 10 topics
Interactions · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
IPR031134 · PF00168
Available protein structures:
IPR031134 · PF00168
CATH
4qam
InterPro
IPR031134
PDB
IPR031134 PF00168 (ECOD; PDBsum)
Pfam
PF00168

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How RPGRIP1 connects Entity context

The extracted context around RPGRIP1 shows recurring relationship patterns in the source. For example, RPGRIP1 → C2, GTPase, N-terminal, Retinitis, RID, RPGR, RPGR-interacting Another extracted example is RPGRIP1 → GTPase, Human X-linked, PDB, PDBe-KB. Use these groups to spot repeated connection types before inspecting the individual relationships.

RPGRIP1

Top relations

related to Interactions · 7
RPGRIP1 → C2, GTPase, N-terminal, Retinitis, RID, RPGR, RPGR-interacting
related to External links · 4
RPGRIP1 → GTPase, Human X-linked, PDB, PDBe-KB
AlphaFold · 2
RPGRIP1 → IPR031134, PF00168
Available protein structures: · 2
RPGRIP1 → IPR031134, PF00168
CATH · 1
RPGRIP1 → 4qam
InterPro · 1
RPGRIP1 → IPR031134
PDB · 1
RPGRIP1 → IPR031134 PF00168 (ECOD; PDBsum)
Pfam · 1
RPGRIP1 → PF00168
SCOP2 · 1
RPGRIP1 → 4qam / SCOPe / SUPFAM
Symbol · 1
RPGRIP1 → X-linked retinitis pigmentosa GTPase regulator-interacting protein 1

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein retinitis pigmentosa gtpase pdb gene x-linked regulator-interacting domain rpgr-interacting rid 4qam c2 structure available n-terminus c-terminal glaucoma ciliary transition

RPGRIP1 relationships Subject–Predicate–Object triples

TTTA extracted 22 structured relationships around RPGRIP1. Examples in this analysis include RPGRIP1 → AlphaFold → IPR031134 and RPGRIP1 → AlphaFold → PF00168. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
RPGRIP1AlphaFoldIPR0311341.00infobox
RPGRIP1AlphaFoldPF001681.00infobox
RPGRIP1Available protein structures:IPR0311341.00infobox
RPGRIP1Available protein structures:PF001681.00infobox
RPGRIP1CATH4qam1.00infobox
RPGRIP1InterProIPR0311341.00infobox
RPGRIP1PDBIPR031134 PF00168 (ECOD; PDBsum)1.00infobox
RPGRIP1PfamPF001681.00infobox
RPGRIP1SCOP24qam / SCOPe / SUPFAM1.00infobox
RPGRIP1SymbolX-linked retinitis pigmentosa GTPase regulator-interacting protein 11.00infobox
RPGRIP1is amulti-domain protein containing a coiled-coil domain at the N-terminus0.90text
RPGRIP1related to External linksPDBe-KB0.60section

Related concept clusters Concept neighborhoods

The concept neighborhoods around RPGRIP1 bring nearby vocabulary together. In this analysis, examples include Domain, Pdb and Rid. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • protein
    • Regulator-interacting
    • Retinitis
    • X-linked
    • Rpgrip1
    • Available
    • Pdb
    • C-terminal
    • Ciliary
    • Coiled-coil
    • Containing
    • Domains
    • Encoded
  • multi-domain protein
    • C-terminal
    • Coiled-coil
    • Containing
    • Domains
    • N-terminus
    • Two
    • Regulator-interacting
    • Retinitis
    • X-linked
    • Rpgrip1
    • Available
    • C2
  • RPGRIP1
    • Domain
    • Pdb
    • Rid
    • Rpgr-interacting
    • X-linked
    • 4qam
    • Available
    • C2
    • Structure
    • C-terminal
    • Coiled-coil
    • Containing
  • rpgrip1
    • Domain
    • Pdb
    • Rid
    • Rpgr-interacting
    • X-linked
    • 4qam
    • Available
    • C2
    • Structure
    • C-terminal
    • Coiled-coil
    • Containing
  • gene
    • Amaurosis
    • Congenital
    • Defects
    • Disease
    • Eye
    • Glaucoma
    • Humans
    • Lca
    • Leber
    • Result
    • Syndrome
    • Transition
  • coiled-coil domain
    • C-terminal
    • Containing
    • Domains
    • Multi-domain
    • N-terminus
    • Rid
    • Rpgr-interacting
    • Two
    • C2
    • Rpgrip1
    • Domain
    • Interactions
  • retinitis pigmentosa gtpase regulator
    • Gtpase
    • Pigmentosa
    • Regulator-interacting
    • Retinitis
    • X-linked
    • Protein
    • Available
    • Pdb
    • Rpgrip1
    • Ciliary
    • Encoded
    • Humans
  • ciliary transition zone
    • Ciliary
    • Encoded
    • Humans
    • Transition
    • Zone
    • Gene
    • Gtpase
    • Pigmentosa
    • Regulator-interacting
    • Retinitis
    • X-linked
    • Protein

Connections between topic areas Semantic bridges

For RPGRIP1, one of the stronger structural bridges in this analysis connects RPGRIP1 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
RPGRIP1 — Overview · splits 6 ⟂ 11
RPGRIP1 — Interactions · splits 12 ⟂ 5

Map overview Semantic statistics

RPGRIP1

Nodes17
Edges16
Triples22
Avg. degree1.88
Density0.117647
Components1

Source & methodology

TTTA analyzes the structure around RPGRIP1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — RPGRIP1 · EN edition · Analysis: TopicsToTalkAbout

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