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Roundabout homolog 1 is a protein that in humans is encoded by the ROBO1 gene.
The analysis highlights Function, Clinical significance and Overview as prominent areas in the source structure around ROBO1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around ROBO1 shows recurring relationship patterns in the source. For example, ROBO1 → activation of cysteine-type endopeptidase activity involved in apoptotic process, aorta development, aortic valve morphogenesis, axon, axon guidance, axon guidance receptor activity, axon midline choice point recognition, cell adhesion, cell differentiation, cell migration involved in sprouting angiogenesis, cell projection, cell surface, chemorepulsion involved in postnatal olfactory bulb interneuron migration, chemotaxis, cytoplasm, development of the heart, endocardial cushion formation, endoplasmic reticulum-Golgi intermediate compartment membrane, homophilic cell adhesion via plasma membrane adhesion molecules, identical protein binding Another extracted example is ROBO1 → Achilles tendon, cumulus cell, ganglionic eminence, genital tubercle, gingival epithelium, Gonadal ridge, habenula, hair follicle, human penis, lateral nuclear group of thalamus, left lung lobe, maxillary prominence, migratory enteric neural crest cell, olfactory tubercle, periodontal fiber, skin of hip, tibia, urethra, ventricular zone, vestibular membrane of cochlear duct. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
bp gene chr human band roundabout chromosome protein midline location guidance receptor mouse nervous system function encoded search 767 998
TTTA extracted 115 structured relationships around ROBO1. Examples in this analysis include ROBO1 → Aliases → ROBO1, DUTT1, SAX3, roundabout guidance receptor 1 and ROBO1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2EO9, 2V9Q, 2V9T, 4HLJ. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| ROBO1 | Aliases | ROBO1, DUTT1, SAX3, roundabout guidance receptor 1 | 1.00 | infobox |
| ROBO1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2EO9, 2V9Q, 2V9T, 4HLJ | 1.00 | infobox |
| ROBO1 | Band | 3p12.3 | 1.00 | infobox |
| ROBO1 | Band | 16|16 C3.1 | 1.00 | infobox |
| ROBO1 | Bgee | ventricular zone | 1.00 | infobox |
| ROBO1 | Bgee | ganglionic eminence | 1.00 | infobox |
| ROBO1 | Bgee | tibia | 1.00 | infobox |
| ROBO1 | Bgee | human penis | 1.00 | infobox |
| ROBO1 | Bgee | Achilles tendon | 1.00 | infobox |
| ROBO1 | Bgee | periodontal fiber | 1.00 | infobox |
| ROBO1 | Bgee | gingival epithelium | 1.00 | infobox |
| ROBO1 | Bgee | lateral nuclear group of thalamus | 1.00 | infobox |
| ROBO1 | Bgee | skin of hip | 1.00 | infobox |
| ROBO1 | Bgee | urethra | 1.00 | infobox |
| ROBO1 | Bgee | genital tubercle | 1.00 | infobox |
| ROBO1 | Bgee | cumulus cell | 1.00 | infobox |
| ROBO1 | Bgee | Gonadal ridge | 1.00 | infobox |
| ROBO1 | Bgee | habenula | 1.00 | infobox |
| ROBO1 | Bgee | vestibular membrane of cochlear duct | 1.00 | infobox |
| ROBO1 | Bgee | hair follicle | 1.00 | infobox |
| ROBO1 | Bgee | olfactory tubercle | 1.00 | infobox |
| ROBO1 | Bgee | maxillary prominence | 1.00 | infobox |
| ROBO1 | Bgee | left lung lobe | 1.00 | infobox |
| ROBO1 | Bgee | migratory enteric neural crest cell | 1.00 | infobox |
| ROBO1 | BioGPS | n/a | 1.00 | infobox |
| ROBO1 | Chr. | Chromosome 3 (human) | 1.00 | infobox |
| ROBO1 | Chr. | Chromosome 16 (mouse) | 1.00 | infobox |
| ROBO1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| ROBO1 | End | 79,767,998 bp | 1.00 | infobox |
| ROBO1 | End | 72,842,983 bp | 1.00 | infobox |
The concept neighborhoods around ROBO1 bring nearby vocabulary together. In this analysis, examples include Roundabout, Gene and Guidance. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For ROBO1, one of the stronger structural bridges in this analysis connects ROBO1 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around ROBO1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Clinical significance & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — ROBO1 · EN edition · Analysis: TopicsToTalkAbout