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E3 ubiquitin-protein ligase Arkadia is an enzyme that in humans is encoded by the RNF111 gene.
The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around RNF111.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around RNF111 shows recurring relationship patterns in the source. For example, RNF111 → cellular response to DNA damage stimulus, cytoplasm, cytosol, DNA repair, global genome nucleotide-excision repair, metal ion binding, multicellular organism development, nucleoplasm, nucleus, pattern specification process, PML body, positive regulation of protein ubiquitination, positive regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, positive regulation of transforming growth factor beta receptor signaling pathway, proteasome-mediated ubiquitin-dependent protein catabolic process, protein binding, protein polyubiquitination, protein ubiquitination, protein-containing complex Another extracted example is RNF111 → aortic valve, blood, cumulus cell, endothelial cell, Epithelium of choroid plexus, epithelium of colon, ganglionic eminence, granulocyte, lymph node, monocyte, parotid gland, pineal gland, primitive streak, secondary oocyte, stromal cell of endometrium, sural nerve, tonsil, ventricular zone, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
bp gene chr human band chromosome 15 mouse location protein enzyme ligase function arkadia encoded search activity 1-q22 097 419
TTTA extracted 96 structured relationships around RNF111. Examples in this analysis include RNF111 → 2.3.2.27 → ↗ and RNF111 → Aliases → RNF111, ARK, ring finger protein 111, hRNF111. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| RNF111 | 2.3.2.27 | ↗ | 1.00 | infobox |
| RNF111 | Aliases | RNF111, ARK, ring finger protein 111, hRNF111 | 1.00 | infobox |
| RNF111 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2KIZ | 1.00 | infobox |
| RNF111 | Band | 15q22.1-q22.2 | 1.00 | infobox |
| RNF111 | Band | 9 D|9 39.53 cM | 1.00 | infobox |
| RNF111 | Bgee | secondary oocyte | 1.00 | infobox |
| RNF111 | Bgee | endothelial cell | 1.00 | infobox |
| RNF111 | Bgee | monocyte | 1.00 | infobox |
| RNF111 | Bgee | ganglionic eminence | 1.00 | infobox |
| RNF111 | Bgee | Epithelium of choroid plexus | 1.00 | infobox |
| RNF111 | Bgee | ventricular zone | 1.00 | infobox |
| RNF111 | Bgee | epithelium of colon | 1.00 | infobox |
| RNF111 | Bgee | stromal cell of endometrium | 1.00 | infobox |
| RNF111 | Bgee | tonsil | 1.00 | infobox |
| RNF111 | Bgee | sural nerve | 1.00 | infobox |
| RNF111 | Bgee | zygote | 1.00 | infobox |
| RNF111 | Bgee | cumulus cell | 1.00 | infobox |
| RNF111 | Bgee | granulocyte | 1.00 | infobox |
| RNF111 | Bgee | primitive streak | 1.00 | infobox |
| RNF111 | Bgee | blood | 1.00 | infobox |
| RNF111 | Bgee | parotid gland | 1.00 | infobox |
| RNF111 | Bgee | pineal gland | 1.00 | infobox |
| RNF111 | Bgee | lymph node | 1.00 | infobox |
| RNF111 | Bgee | aortic valve | 1.00 | infobox |
| RNF111 | BioGPS | More reference expression data | 1.00 | infobox |
| RNF111 | Chr. | Chromosome 15 (human) | 1.00 | infobox |
| RNF111 | Chr. | Chromosome 9 (mouse) | 1.00 | infobox |
| RNF111 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| RNF111 | End | 59,097,419 bp | 1.00 | infobox |
| RNF111 | End | 70,411,007 bp | 1.00 | infobox |
The concept neighborhoods around RNF111 bring nearby vocabulary together. In this analysis, examples include Gene, Activity and Development. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For RNF111, one of the stronger structural bridges in this analysis connects RNF111 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around RNF111 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — RNF111 · EN edition · Analysis: TopicsToTalkAbout