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Revumenib, sold under the brand name Revuforj, is an anti-cancer medication used for the treatment of acute leukemias harboring lysine methyltransferase 2A gene (KMT2A) rearrangements. It is designed to disrupt the interaction between menin and KMT2A (also known as MLL), which plays a role in the pathogenesis of these leukemias. It is taken by mouth.
The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Revumenib.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Revumenib shows recurring relationship patterns in the source. For example, Revumenib → Archived, AUGMENT-101, Clinical, ClinicalTrials, Code C165776, December, Expanded Access Program, MLL/KMT2A Gene Rearrangement, NCI Drug Dictionary, NCI Thesaurus, NCT04065399, NCT05918913, NPM1 Mutation, R/R Leukemias Including Those, Study, With Another extracted example is Revumenib → AUGMENT-101, Drug Administration, Efficacy, FDA, NCT04065399, Participants, R/R, SNDX-5613-0700, The US Food. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
kmt2a treatment acute name us drug menin gene 2024 leukemias adverse medical revuforj administration leukemia lysine methyltransferase 2a differentiation syndrome
TTTA extracted 58 structured relationships around Revumenib. Examples in this analysis include Revumenib → 3D model (JSmol) → Interactive image and Revumenib → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Revumenib | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| Revumenib | AHFS/Drugs.com | Monograph | 1.00 | infobox |
| Revumenib | ATC code | L01XX87 (WHO) | 1.00 | infobox |
| Revumenib | CAS Number | 2169919-21-3 | 1.00 | infobox |
| Revumenib | CAS Number | 2169919-22-4 | 1.00 | infobox |
| Revumenib | ChEMBL | ChEMBL4650827 | 1.00 | infobox |
| Revumenib | ChEMBL | ChEMBL4650278 | 1.00 | infobox |
| Revumenib | ChemSpider | 95502909 | 1.00 | infobox |
| Revumenib | Drug class | Antineoplastic; menin inhibitor | 1.00 | infobox |
| Revumenib | DrugBank | DB18515 | 1.00 | infobox |
| Revumenib | DrugBank | DBSALT003460 | 1.00 | infobox |
| Revumenib | Formula | C32H47FN6O4S | 1.00 | infobox |
| Revumenib | KEGG | D12728 | 1.00 | infobox |
| Revumenib | KEGG | D12729 | 1.00 | infobox |
| Revumenib | Legal status | US: ℞-only | 1.00 | infobox |
| Revumenib | License data | US DailyMed: Revumenib | 1.00 | infobox |
| Revumenib | MedlinePlus | a624077 | 1.00 | infobox |
| Revumenib | Molar mass | 630.82 g·mol−1 | 1.00 | infobox |
| Revumenib | Other names | SNDX-5613 | 1.00 | infobox |
| Revumenib | PDB ligand | OQ4 (PDBe, RCSB PDB) | 1.00 | infobox |
| Revumenib | Pronunciation | /rɪˈvuːmɛnɪb/ rih-VOO-meh-nib | 1.00 | infobox |
| Revumenib | PubChem CID | 132212657 | 1.00 | infobox |
| Revumenib | Routes of administration | By mouth | 1.00 | infobox |
| Revumenib | Trade names | Revuforj | 1.00 | infobox |
| Revumenib | UNII | LZ0M43NNF2 | 1.00 | infobox |
| Revumenib | UNII | 75HI05N8HS | 1.00 | infobox |
The concept neighborhoods around Revumenib bring nearby vocabulary together. In this analysis, examples include Treatment, Medical and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Revumenib, one of the stronger structural bridges in this analysis connects Revumenib with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Revumenib to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Revumenib · EN edition · Analysis: TopicsToTalkAbout