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Ramipril

Ramipril, sold under the brand name Altace among others, is an ACE inhibitor type medication used to treat high blood pressure, heart failure, and diabetic kidney disease. It can also be used as a preventative medication in patients over 55 years old to reduce the risk of having a heart attack, stroke or cardiovascular death in patients shown to be at…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
C09AA05 (WHO)
Bioavailability
28%
CAS Number
87333-19-5 Y
ChEBI
CHEBI:8774 Y

Topics to explore

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Overview

Activation and binding

Medical uses

Contraindications

Adverse effects

Mechanism of action

Synthesis

Society and culture

Research

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Map overview Semantic statistics

Ramipril

Nodes70
Edges69
Triples74
Avg. degree1.97
Density0.028571
Components1

How this topic connects Entity context

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Ramipril

Top relations

related to US patent · 13
Ramipril → Appeals, Aventis, Aventis's, Federal Circuit, German, Hoechst AG, Indian, Lupin Ltd, October, On, September, The, United States Court
related to Research · 7
Ramipril → AIRE, Efficacy, Heart Outcomes, However, Prevention Evaluation, The, The Acute Infarction Ramipril
has effect · 6
Ramipril → Chest, Hyperkalemia Serious, Impotence, In, ShakinessDry, Symptoms
related to Activation and binding · 6
Ramipril → ACE, ACE Inhibitor, OCH2CH3, The, This, Zn2
related to Mechanism of action · 6
Ramipril → ACE, II, Its, Peak, Ramiprilat, The
related to Contraindications · 4
Ramipril → ACE, Contraindications, It, People
Legal status · 3
Ramipril → CA: ℞-only, UK: POM (Prescription only), US: ℞-only
related to Synthesis · 2
Ramipril → In, The
3D model (JSmol) · 1
Ramipril → Interactive image
AHFS/Drugs.com · 1
Ramipril → Monograph

Important terminology Word statistics

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Important terminology

blood high kidney ace heart medication patients pressure include inhibitor disease liver medical effects mouth trial failure side use patent

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Ramipril3D model (JSmol)Interactive image1.00infobox
RamiprilAHFS/Drugs.comMonograph1.00infobox
RamiprilATC codeC09AA05 (WHO)1.00infobox
RamiprilBioavailability28%1.00infobox
RamiprilCAS Number87333-19-5 Y1.00infobox
RamiprilChEBICHEBI:8774 Y1.00infobox
RamiprilChEMBLChEMBL1168 Y1.00infobox
RamiprilChemSpider4514937 Y1.00infobox
RamiprilCompTox Dashboard (EPA)DTXSID80235511.00infobox
RamiprilDrugBankDB00178 Y1.00infobox
RamiprilECHA InfoCard100.170.7261.00infobox
RamiprilElimination half-life13 to 17 hours1.00infobox
RamiprilExcretionKidney (60%) and fecal (40%)1.00infobox
RamiprilFormulaC23H32N2O51.00infobox
RamiprilIUPHAR/BPS63391.00infobox
RamiprilKEGGD00421 Y1.00infobox
RamiprilLegal statusCA: ℞-only1.00infobox
RamiprilLegal statusUK: POM (Prescription only)1.00infobox
RamiprilLegal statusUS: ℞-only1.00infobox
RamiprilLicense dataUS DailyMed: Ramipril1.00infobox
RamiprilMedlinePlusa6920271.00infobox
RamiprilMelting point109 °C (228 °F)1.00infobox
RamiprilMetabolismLiver, to ramiprilat1.00infobox
RamiprilMolar mass416.518 g·mol−11.00infobox
RamiprilProtein binding73% (ramipril) 56% (ramiprilat)1.00infobox
RamiprilPubChem CID53621291.00infobox
RamiprilRoutes of administrationBy mouth1.00infobox
RamiprilTrade namesAltace, others1.00infobox
RamiprilUNIIL35JN3I7SJ1.00infobox
Ramiprilis aproduct after the benzyl ester has been removed by hydrogenation0.90text

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