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Ramipril: Community, Culture, Applications & Research

Ramipril, sold under the brand name Altace among others, is an ACE inhibitor type medication used to treat high blood pressure, heart failure, and diabetic kidney disease. It can also be used as a preventative medication in patients over 55 years old to reduce the risk of having a heart attack, stroke or cardiovascular death in patients shown to be at…

Language: English [EN]
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Ramipril topic overview

The analysis highlights Community, Culture, Applications and Research as prominent areas in the source structure around Ramipril.

Related topics
60
Source areas
9
Connected nodes
69
Extracted relationships
74
Concept neighborhoods
21
Bridge connections
69

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Mechanism of action · 14 topics
Overview · 11 topics
Activation and binding · 7 topics
Adverse effects · 7 topics
Synthesis · 7 topics
Contraindications · 5 topics
Society and culture · 4 topics
Medical uses · 3 topics
Research · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
C09AA05 (WHO)
Bioavailability
28%
CAS Number
87333-19-5 Y
ChEBI
CHEBI:8774 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Activation and binding

Medical uses

Contraindications

Adverse effects

Mechanism of action

Synthesis

Society and culture

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Ramipril connects Entity context

The extracted context around Ramipril shows recurring relationship patterns in the source. For example, Ramipril → Appeals, Aventis, Aventis's, Federal Circuit, German, Hoechst AG, Indian, Lupin Ltd, October, On, September, The, United States Court Another extracted example is Ramipril → AIRE, Efficacy, Heart Outcomes, However, Prevention Evaluation, The, The Acute Infarction Ramipril. Use these groups to spot repeated connection types before inspecting the individual relationships.

Ramipril

Top relations

related to US patent · 13
Ramipril → Appeals, Aventis, Aventis's, Federal Circuit, German, Hoechst AG, Indian, Lupin Ltd, October, On, September, The, United States Court
related to Research · 7
Ramipril → AIRE, Efficacy, Heart Outcomes, However, Prevention Evaluation, The, The Acute Infarction Ramipril
has effect · 6
Ramipril → Chest, Hyperkalemia Serious, Impotence, In, ShakinessDry, Symptoms
related to Activation and binding · 6
Ramipril → ACE, ACE Inhibitor, OCH2CH3, The, This, Zn2
related to Mechanism of action · 6
Ramipril → ACE, II, Its, Peak, Ramiprilat, The
related to Contraindications · 4
Ramipril → ACE, Contraindications, It, People
Legal status · 3
Ramipril → CA: ℞-only, UK: POM (Prescription only), US: ℞-only
related to Synthesis · 2
Ramipril → In, The
3D model (JSmol) · 1
Ramipril → Interactive image
AHFS/Drugs.com · 1
Ramipril → Monograph

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

blood high kidney ace heart medication patients pressure include inhibitor disease liver medical effects mouth trial failure side use patent

Ramipril relationships Subject–Predicate–Object triples

TTTA extracted 74 structured relationships around Ramipril. Examples in this analysis include Ramipril → 3D model (JSmol) → Interactive image and Ramipril → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Ramipril3D model (JSmol)Interactive image1.00infobox
RamiprilAHFS/Drugs.comMonograph1.00infobox
RamiprilATC codeC09AA05 (WHO)1.00infobox
RamiprilBioavailability28%1.00infobox
RamiprilCAS Number87333-19-5 Y1.00infobox
RamiprilChEBICHEBI:8774 Y1.00infobox
RamiprilChEMBLChEMBL1168 Y1.00infobox
RamiprilChemSpider4514937 Y1.00infobox
RamiprilCompTox Dashboard (EPA)DTXSID80235511.00infobox
RamiprilDrugBankDB00178 Y1.00infobox
RamiprilECHA InfoCard100.170.7261.00infobox
RamiprilElimination half-life13 to 17 hours1.00infobox
RamiprilExcretionKidney (60%) and fecal (40%)1.00infobox
RamiprilFormulaC23H32N2O51.00infobox
RamiprilIUPHAR/BPS63391.00infobox
RamiprilKEGGD00421 Y1.00infobox
RamiprilLegal statusCA: ℞-only1.00infobox
RamiprilLegal statusUK: POM (Prescription only)1.00infobox
RamiprilLegal statusUS: ℞-only1.00infobox
RamiprilLicense dataUS DailyMed: Ramipril1.00infobox
RamiprilMedlinePlusa6920271.00infobox
RamiprilMelting point109 °C (228 °F)1.00infobox
RamiprilMetabolismLiver, to ramiprilat1.00infobox
RamiprilMolar mass416.518 g·mol−11.00infobox
RamiprilProtein binding73% (ramipril) 56% (ramiprilat)1.00infobox
RamiprilPubChem CID53621291.00infobox
RamiprilRoutes of administrationBy mouth1.00infobox
RamiprilTrade namesAltace, others1.00infobox
RamiprilUNIIL35JN3I7SJ1.00infobox
Ramiprilis aproduct after the benzyl ester has been removed by hydrogenation0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Ramipril bring nearby vocabulary together. In this analysis, examples include Patients, Acid and Trial. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Ramipril
    • Patients
    • Acid
    • Trial
    • Heart
    • Ramiprilat
    • Use
    • Failure
    • Liver
    • Medical
    • Patent
    • Kidney
    • Blood
  • ramipril
    • Patients
    • Acid
    • Trial
    • Heart
    • Ramiprilat
    • Use
    • Failure
    • Liver
    • Medical
    • Patent
    • Kidney
    • Blood
  • high blood pressure
    • Pressure
    • Disease
    • Blood
    • High
    • Stroke
    • Used
    • Heart
    • Kidney
    • Cardiovascular
    • Death
    • Diabetic
    • Failure
  • diabetic kidney disease
    • Cardiovascular
    • Death
    • Disease
    • High
    • Kidney
    • Stroke
    • Used
    • Heart
    • Liver
    • Failure
    • Medication
    • Name
  • kidney problems
    • Disease
    • Liver
    • Name
    • Others
    • Cardiovascular
    • Death
    • Effects
    • Hours
    • Medical
    • Include
    • Pressure
    • Binding
  • high blood potassium
    • Pressure
    • Disease
    • Blood
    • High
    • Stroke
    • Used
    • Heart
    • Kidney
    • Cardiovascular
    • Death
    • Diabetic
    • Failure
  • liver failure
    • Heart
    • Kidney
    • Diabetic
    • Hours
    • Disease
    • High
    • Pressure
    • Binding
    • Us
    • Angioedema
    • Name
    • Others
  • kidney failure
    • Heart
    • Disease
    • Kidney
    • Liver
    • Diabetic
    • Name
    • Others
    • Cardiovascular
    • Death
    • Effects
    • High
    • Hours

Connections between topic areas Semantic bridges

For Ramipril, one of the stronger structural bridges in this analysis connects Ramipril with Mechanism of action. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Ramipril — Mechanism of action · splits 55 ⟂ 15
Ramipril — Overview · splits 58 ⟂ 12
Ramipril — Activation and binding · splits 62 ⟂ 8
Ramipril — Adverse effects · splits 62 ⟂ 8
Ramipril — Synthesis · splits 62 ⟂ 8
Ramipril — Contraindications · splits 64 ⟂ 6
Ramipril — Society and culture · splits 65 ⟂ 5
Ramipril — Medical uses · splits 66 ⟂ 4
Ramipril — Research · splits 67 ⟂ 3

Map overview Semantic statistics

Ramipril

Nodes70
Edges69
Triples74
Avg. degree1.97
Density0.028571
Components1

Source & methodology

TTTA analyzes the structure around Ramipril to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Community, Culture, Applications & Research, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Ramipril · EN edition · Analysis: TopicsToTalkAbout

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