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PTBP1: Interactions, Evolution & Overview

Polypyrimidine tract-binding protein 1 is a protein that in humans is encoded by the PTBP1 gene.

Language: English [EN]
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PTBP1 topic overview

The analysis highlights Interactions, Evolution and Overview as prominent areas in the source structure around PTBP1.

Related topics
10
Source areas
3
Connected nodes
13
Extracted relationships
90
Concept neighborhoods
5
Bridge connections
13

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 7 topics
Overview · 2 topics
Evolution · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
PTBP1, HNRNP-I, HNRNPI, HNRPI, PTB, PTB-1, PTB-T, PTB2, PTB3, PTB4, pPTB, polypyrimidine tract binding protein 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1QM9, 1SJQ, 1SJR, 2AD9, 2ADB, 2ADC, 2EVZ, 3ZZY, 3ZZZ
Band
19p13.3 · 10 C1|10 39.72 cM
Bgee
thymus · nipple · mucosa of pharynx · stromal cell of endometrium · human penis
BioGPS
More reference expression data
Chr.
Chromosome 19 (human) · Chromosome 10 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Evolution

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How PTBP1 connects Entity context

The extracted context around PTBP1 shows recurring relationship patterns in the source. For example, PTBP1 → extracellular exosome, fibroblast growth factor receptor signaling pathway, IRES-dependent viral translational initiation, membrane, mRNA processing, mRNA splicing, via spliceosome, negative regulation of mRNA splicing, via spliceosome, negative regulation of muscle cell differentiation, negative regulation of RNA splicing, nucleic acid binding, nucleolus, nucleoplasm, nucleus, poly-pyrimidine tract binding, positive regulation of calcineurin-NFAT signaling cascade, positive regulation of protein dephosphorylation, pre-mRNA binding, protein binding, regulation of alternative mRNA splicing, via spliceosome, RNA binding Another extracted example is PTBP1 → blastocyst, cecum, embryo, genital tubercle, human penis, islet of Langerhans, lip, morula, mucosa of pharynx, nipple, pancreatic ductal cell, pylorus, stromal cell of endometrium, tail of embryo, thymus, ventricular zone, yolk sac, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

PTBP1

Top relations

Gene ontology · 22
PTBP1 → extracellular exosome, fibroblast growth factor receptor signaling pathway, IRES-dependent viral translational initiation, membrane, mRNA processing, mRNA splicing, via spliceosome, negative regulation of mRNA splicing, via spliceosome, negative regulation of muscle cell differentiation, negative regulation of RNA splicing, nucleic acid binding, nucleolus, nucleoplasm, nucleus, poly-pyrimidine tract binding, positive regulation of calcineurin-NFAT signaling cascade, positive regulation of protein dephosphorylation, pre-mRNA binding, protein binding, regulation of alternative mRNA splicing, via spliceosome, RNA binding
Bgee · 18
PTBP1 → blastocyst, cecum, embryo, genital tubercle, human penis, islet of Langerhans, lip, morula, mucosa of pharynx, nipple, pancreatic ductal cell, pylorus, stromal cell of endometrium, tail of embryo, thymus, ventricular zone, yolk sac, zygote
RNA expression pattern · 18
PTBP1 → blastocyst, cecum, embryo, genital tubercle, human penis, islet of Langerhans, lip, morula, mucosa of pharynx, nipple, pancreatic ductal cell, pylorus, stromal cell of endometrium, tail of embryo, thymus, ventricular zone, yolk sac, zygote
related to Interactions · 7
PTBP1 → During, HNRNPL, HNRPK, PCBP2, PTBP2, SFPQ, This
Band · 2
PTBP1 → 10 C1|10 39.72 cM, 19p13.3
Chr. · 2
PTBP1 → Chromosome 10 (mouse), Chromosome 19 (human)
End · 2
PTBP1 → 79,700,605 bp, 812,327 bp
related to Evolution · 2
PTBP1 → In, This
Aliases · 1
PTBP1 → PTBP1, HNRNP-I, HNRNPI, HNRPI, PTB, PTB-1, PTB-T, PTB2, PTB3, PTB4, pPTB, polypyrimidine tract binding protein 1
Available structures · 1
PTBP1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1QM9, 1SJQ, 1SJR, 2AD9, 2ADB, 2ADC, 2EVZ, 3ZZY, 3ZZZ

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene protein bp chr human band binding chromosome 19 hnrnps proteins nucleus polypyrimidine pre-mrna mrna splicing location encoded heterogeneous nuclear

PTBP1 relationships Subject–Predicate–Object triples

TTTA extracted 90 structured relationships around PTBP1. Examples in this analysis include PTBP1 → Aliases → PTBP1, HNRNP-I, HNRNPI, HNRPI, PTB, PTB-1, PTB-T, PTB2, PTB3, PTB4, pPTB, polypyrimidine tract binding protein 1 and PTBP1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1QM9, 1SJQ, 1SJR, 2AD9, 2ADB, 2ADC, 2EVZ, 3ZZY, 3ZZZ. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
PTBP1AliasesPTBP1, HNRNP-I, HNRNPI, HNRPI, PTB, PTB-1, PTB-T, PTB2, PTB3, PTB4, pPTB, polypyrimidine tract binding protein 11.00infobox
PTBP1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1QM9, 1SJQ, 1SJR, 2AD9, 2ADB, 2ADC, 2EVZ, 3ZZY, 3ZZZ1.00infobox
PTBP1Band19p13.31.00infobox
PTBP1Band10 C1|10 39.72 cM1.00infobox
PTBP1Bgeethymus1.00infobox
PTBP1Bgeenipple1.00infobox
PTBP1Bgeemucosa of pharynx1.00infobox
PTBP1Bgeestromal cell of endometrium1.00infobox
PTBP1Bgeehuman penis1.00infobox
PTBP1Bgeepancreatic ductal cell1.00infobox
PTBP1Bgeepylorus1.00infobox
PTBP1Bgeeislet of Langerhans1.00infobox
PTBP1Bgeececum1.00infobox
PTBP1Bgeeventricular zone1.00infobox
PTBP1Bgeetail of embryo1.00infobox
PTBP1Bgeegenital tubercle1.00infobox
PTBP1Bgeezygote1.00infobox
PTBP1Bgeeyolk sac1.00infobox
PTBP1Bgeelip1.00infobox
PTBP1Bgeeembryo1.00infobox
PTBP1Bgeemorula1.00infobox
PTBP1Bgeeblastocyst1.00infobox
PTBP1BioGPSMore reference expression data1.00infobox
PTBP1Chr.Chromosome 19 (human)1.00infobox
PTBP1Chr.Chromosome 10 (mouse)1.00infobox
PTBP1DatabasesNCBI: entry; OMA: entry1.00infobox
PTBP1End812,327 bp1.00infobox
PTBP1End79,700,605 bp1.00infobox
PTBP1EnsemblENSG000000113041.00infobox
PTBP1Entrez57251.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around PTBP1 bring nearby vocabulary together. In this analysis, examples include Search, Tract and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • protein
    • Ptbp1
    • Nucleoplasm
    • Pathway
    • Search
    • Splicing
    • Tract
    • Via
    • Location
    • Mrna
    • Pre-mrna
    • Binding
    • Chromosome
  • gene
    • Location
    • Protein
    • Chromosome
    • Human
    • Bp
    • Chr
    • Ptbp1
    • C1
    • End
    • Expressed
    • Mouse
    • Search
  • PTBP1
    • Search
    • Tract
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • C1
    • End
    • Mouse
    • Rna
    • Spliced
  • ptbp1
    • Search
    • Tract
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • C1
    • End
    • Mouse
    • Rna
    • Spliced
  • alternative splicing
    • Via
    • C1
    • End
    • Mouse
    • Nucleoplasm
    • Rna
    • Search
    • Tract
    • Location
    • Band
    • Chromosome
    • Human

Connections between topic areas Semantic bridges

For PTBP1, one of the stronger structural bridges in this analysis connects PTBP1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
PTBP1Interactions · splits 6 ⟂ 8
PTBP1Overview · splits 11 ⟂ 3

Map overview Semantic statistics

PTBP1

Nodes14
Edges13
Triples90
Avg. degree1.86
Density0.142857
Components1

Source & methodology

TTTA analyzes the structure around PTBP1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Evolution & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PTBP1 · EN edition · Analysis: TopicsToTalkAbout

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