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DNA polymerase I

DNA polymerase I (or Pol I) is an enzyme that participates in the process of prokaryotic DNA replication. Discovered by Arthur Kornberg in 1956, it was the first known DNA polymerase (and the first known of any kind of polymerase). It was initially characterized in E. coli and is ubiquitous in prokaryotes. In E. coli and many other bacteria, the gene…

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Chromosome
genome: 4.04 - 4.05 Mb
Domains
InterPro
EC number
2.7.7.7
Entrez
948356
Organism
Escherichia coli (str. K-12 substr. MG1655)
Orthologs
NCBI: entry; OMA: entry

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Mechanism

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DNA polymerase I

Nodes53
Edges52
Triples48
Avg. degree1.96
Density0.037736
Components1

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DNA polymerase I

Top relations

related to Mechanism · 24
DNA polymerase I → Additionally, Cairns, De Lucia, Despite, DNA, DNA-polymerase, However, III, In, It, Its, John Cairns, Moreover, Nevertheless, Okazaki, Once, Paula, Paula De Lucia, Pol, Polymerase
has application · 9
DNA polymerase I → DNA, Exposure, However, In, Klenow, PCR, Taq Polymerase, Thermus, This
see also · 3
DNA polymerase I → DNA, IIDNA, IIIDNA
Chromosome · 1
DNA polymerase I → genome: 4.04 - 4.05 Mb
Domains · 1
DNA polymerase I → InterPro
EC number · 1
DNA polymerase I → 2.7.7.7
Entrez · 1
DNA polymerase I → 948356
Organism · 1
DNA polymerase I → Escherichia coli (str. K-12 substr. MG1655)
Orthologs · 1
DNA polymerase I → NCBI: entry; OMA: entry
PDB · 1
DNA polymerase I → 1DPI

Important terminology Word statistics

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Important terminology

dna polymerase pol coli rna replication nucleotides domain strand template known polymerases primer 3' also activity 5' mutant synthesis site

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
DNA polymerase IChromosomegenome: 4.04 - 4.05 Mb1.00infobox
DNA polymerase IDomainsInterPro1.00infobox
DNA polymerase IEC number2.7.7.71.00infobox
DNA polymerase IEntrez9483561.00infobox
DNA polymerase IOrganismEscherichia coli (str. K-12 substr. MG1655)1.00infobox
DNA polymerase IOrthologsNCBI: entry; OMA: entry1.00infobox
DNA polymerase IPDB1DPI1.00infobox
DNA polymerase IRefSeq (Prot)NP_418300.11.00infobox
DNA polymerase ISearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
DNA polymerase IStructuresSwiss-model1.00infobox
DNA polymerase ISymbolpolA1.00infobox
DNA polymerase IUniProtP005821.00infobox

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