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FXYD family

The FXYD protein family is a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the amino acid sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator.

Human proteins containing this domain & Overview

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Human proteins containing this domain

FXYD1FXYD2FXYD3FXYD4FXYD5
9 related topics

Overview

Membrane proteinsAmino acid sequenceOrthologsGlycinesSerine
9 related topics

Key facts & relationships

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AlphaFold
IPR000272 · PF02038
Available protein structures:
IPR000272 · PF02038
InterPro
IPR000272
Membranome
382
OPM protein
2jo1
OPM superfamily
62

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Overview

Human proteins containing this domain

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Map overview Semantic statistics

FXYD family

Nodes21
Edges20
Triples13
Avg. degree1.9
Density0.095238
Components1

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FXYD family

Top relations

AlphaFold · 2
FXYD family → IPR000272, PF02038
Available protein structures: · 2
FXYD family → IPR000272, PF02038
InterPro · 1
FXYD family → IPR000272
Membranome · 1
FXYD family → 382
OPM protein · 1
FXYD family → 2jo1
OPM superfamily · 1
FXYD family → 62
PDB · 1
FXYD family → IPR000272 PF02038 (ECOD; PDBsum)
Pfam · 1
FXYD family → PF02038
PROSITE · 1
FXYD family → PS01310
Symbol · 1
FXYD family → ATP1G1_PLM_MAT8

Important terminology Word statistics

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Important terminology

fxyd proteins protein na k-atpase family transport domain containing share signature sequence amino conserved acids ion members two mammalian functional

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
FXYD familyAlphaFoldIPR0002721.00infobox
FXYD familyAlphaFoldPF020381.00infobox
FXYD familyAvailable protein structures:IPR0002721.00infobox
FXYD familyAvailable protein structures:PF020381.00infobox
FXYD familyInterProIPR0002721.00infobox
FXYD familyMembranome3821.00infobox
FXYD familyOPM protein2jo11.00infobox
FXYD familyOPM superfamily621.00infobox
FXYD familyPDBIPR000272 PF02038 (ECOD; PDBsum)1.00infobox
FXYD familyPfamPF020381.00infobox
FXYD familyPROSITEPS013101.00infobox
FXYD familySymbolATP1G1_PLM_MAT81.00infobox
FXYD familyTCDB1.A.271.00infobox

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