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Pholcodine: Products, Side effects & Mechanism of action

Pholcodine is an opioid cough suppressant (antitussive). It helps suppress unproductive coughs and also has a mild sedative effect, but has little or no analgesic effects. It is also known as morpholinylethylmorphine and homocodeine.

Language: English [EN]
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Pholcodine topic overview

The analysis highlights Products, Side effects and Mechanism of action as prominent areas in the source structure around Pholcodine.

Related topics
35
Source areas
5
Connected nodes
40
Extracted relationships
53
Concept neighborhoods
16
Bridge connections
40

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 12 topics
Side effects · 9 topics
Mechanism of action · 8 topics
Anaphylaxis during general anaesthesia · 3 topics
Metabolism and excretion · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
Addiction liability
High
AHFS/Drugs.com
International Drug Names
ATC code
R05DA08 (WHO)
Bioavailability
Maximum plasma conc. attained 4-8 hours after oral dose.
CAS Number
509-67-1

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Mechanism of action

Metabolism and excretion

Side effects

Anaphylaxis during general anaesthesia

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Pholcodine connects Entity context

The extracted context around Pholcodine shows recurring relationship patterns in the source. For example, Pholcodine → Administration, However, NMBAs, Norway, Sweden, The, These Another extracted example is Pholcodine → BR: Class A2 (Narcotic drugs), CA: Schedule I, DE: Anlage II (Authorized trade only, not prescriptible), UK: Class B, US: Schedule I. Use these groups to spot repeated connection types before inspecting the individual relationships.

Pholcodine

Top relations

related to Anaphylaxis during general anaesthesia · 7
Pholcodine → Administration, However, NMBAs, Norway, Sweden, The, These
Legal status · 5
Pholcodine → BR: Class A2 (Narcotic drugs), CA: Schedule I, DE: Anlage II (Authorized trade only, not prescriptible), UK: Class B, US: Schedule I
related to Metabolism and excretion · 4
Pholcodine → Nearly, The, This, With
has effect · 3
Pholcodine → Adverse, Side, The
related to Mechanism of action · 3
Pholcodine → CNS, It, Its
3D model (JSmol) · 1
Pholcodine → Interactive image
Addiction liability · 1
Pholcodine → High
AHFS/Drugs.com · 1
Pholcodine → International Drug Names
ATC code · 1
Pholcodine → R05DA08 (WHO)
Bioavailability · 1
Pholcodine → Maximum plasma conc. attained 4-8 hours after oral dose.

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

anaphylaxis 2023 drug administration products medicines liver anaesthesia effects general use nmbas risk european cough withdrawn agency dose uk containing

Pholcodine relationships Subject–Predicate–Object triples

TTTA extracted 53 structured relationships around Pholcodine. Examples in this analysis include Pholcodine → 3D model (JSmol) → Interactive image and Pholcodine → Addiction liability → High. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Pholcodine3D model (JSmol)Interactive image1.00infobox
PholcodineAddiction liabilityHigh1.00infobox
PholcodineAHFS/Drugs.comInternational Drug Names1.00infobox
PholcodineATC codeR05DA08 (WHO)1.00infobox
PholcodineBioavailabilityMaximum plasma conc. attained 4-8 hours after oral dose.1.00infobox
PholcodineCAS Number509-67-11.00infobox
PholcodineChEBICHEBI:535791.00infobox
PholcodineChEMBLChEMBL21052241.00infobox
PholcodineChemSpider44708541.00infobox
PholcodineCompTox Dashboard (EPA)DTXSID701989231.00infobox
PholcodineDrugBankDB092091.00infobox
PholcodineECHA InfoCard100.007.3671.00infobox
PholcodineElimination half-life32-43 hours; volume of distribution is 36-49L/kg.1.00infobox
PholcodineExcretionKidney1.00infobox
PholcodineFormulaC23H30N2O41.00infobox
PholcodineKEGGD073851.00infobox
PholcodineLegal statusBR: Class A2 (Narcotic drugs)1.00infobox
PholcodineLegal statusCA: Schedule I1.00infobox
PholcodineLegal statusDE: Anlage II (Authorized trade only, not prescriptible)1.00infobox
PholcodineLegal statusUK: Class B1.00infobox
PholcodineLegal statusUS: Schedule I1.00infobox
PholcodineMetabolismLiver1.00infobox
PholcodineMolar mass398.503 g·mol−11.00infobox
PholcodineProtein binding23.5%1.00infobox
PholcodinePubChem CID53113561.00infobox
PholcodineRoutes of administrationBy mouth1.00infobox
PholcodineTrade namesLogicin, others1.00infobox
PholcodineUNIILPP64AWZ7L1.00infobox
Pholcodinecausesproduction of antibodies linked with fatalities during surgery0.90text
Pholcodineis aopioid cough suppressant0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Pholcodine bring nearby vocabulary together. In this analysis, examples include Containing, General and Administration. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Pholcodine
    • Containing
    • General
    • Administration
    • Products
    • High
    • Nmbas
    • Risk
    • Use
    • Anaesthesia
    • Excretion
    • Schedule
    • Antibodies
  • pholcodine
    • Containing
    • General
    • Administration
    • Products
    • High
    • Nmbas
    • Risk
    • Use
    • Anaesthesia
    • Excretion
    • Schedule
    • Antibodies
  • anaphylaxis
    • High
    • Us
    • Risk
    • Pholcodine
    • European
    • Medicines
    • Nmbas
    • Use
    • Anaesthesia
    • Antitussive
    • Concerns
    • Excretion
  • anaphylaxis during general anaesthesia
    • Anaesthesia
    • General
    • Antibodies
    • High
    • Nmbas
    • Us
    • Risk
    • Administration
    • Pholcodine
    • Excretion
    • Metabolism
    • Oral
  • therapeutic goods administration
    • Goods
    • Therapeutic
    • Administration
    • General
    • Anaesthesia
    • Pholcodine
    • Containing
    • Excretion
    • Metabolism
    • Oral
    • Schedule
    • Antibodies
  • general anaesthesia
    • Anaesthesia
    • General
    • Antibodies
    • Nmbas
    • Administration
    • Excretion
    • Metabolism
    • Oral
    • Schedule
    • Pholcodine
    • Anaphylaxis
    • Concerns
  • medicines and healthcare products regulatory agency
    • Containing
    • Medicines
    • European
    • Risk
    • Uk
    • Use
    • Products
    • Data
    • Withdrawn
    • Goods
    • Nmbas
    • Norway
  • urine drug testing
    • Schedule
    • Dose
    • Excretion
    • Metabolism
    • Oral
    • High
    • Uk
    • Us
    • Effects
    • General
    • Administration
    • Anaesthesia

Connections between topic areas Semantic bridges

For Pholcodine, one of the stronger structural bridges in this analysis connects Pholcodine with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
PholcodineOverview · splits 28 ⟂ 13
PholcodineSide effects · splits 31 ⟂ 10
PholcodineMechanism of action · splits 32 ⟂ 9
PholcodineMetabolism and excretion · splits 37 ⟂ 4
PholcodineAnaphylaxis during general anaesthesia · splits 37 ⟂ 4

Map overview Semantic statistics

Pholcodine

Nodes41
Edges40
Triples53
Avg. degree1.95
Density0.04878
Components1

Source & methodology

TTTA analyzes the structure around Pholcodine to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Products, Side effects & Mechanism of action, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Pholcodine · EN edition · Analysis: TopicsToTalkAbout

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