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Pholcodine

Pholcodine is an opioid cough suppressant (antitussive). It helps suppress unproductive coughs and also has a mild sedative effect, but has little or no analgesic effects. It is also known as morpholinylethylmorphine and homocodeine.

Products, Side effects & Mechanism of action

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Explore the main themes, entities and connections around Pholcodine. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Key facts & relationships

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3D model (JSmol)
Interactive image
Addiction liability
High
AHFS/Drugs.com
International Drug Names
ATC code
R05DA08 (WHO)
Bioavailability
Maximum plasma conc. attained 4-8 hours after oral dose.
CAS Number
509-67-1

Topics to explore

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Overview

Mechanism of action

Metabolism and excretion

Side effects

Anaphylaxis during general anaesthesia

Advanced semantic analysis

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Map overview Semantic statistics

Pholcodine

Nodes41
Edges40
Triples53
Avg. degree1.95
Density0.04878
Components1

How this topic connects Entity context

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Pholcodine

Top relations

related to Anaphylaxis during general anaesthesia · 7
Pholcodine → Administration, However, NMBAs, Norway, Sweden, The, These
Legal status · 5
Pholcodine → BR: Class A2 (Narcotic drugs), CA: Schedule I, DE: Anlage II (Authorized trade only, not prescriptible), UK: Class B, US: Schedule I
related to Metabolism and excretion · 4
Pholcodine → Nearly, The, This, With
has effect · 3
Pholcodine → Adverse, Side, The
related to Mechanism of action · 3
Pholcodine → CNS, It, Its
3D model (JSmol) · 1
Pholcodine → Interactive image
Addiction liability · 1
Pholcodine → High
AHFS/Drugs.com · 1
Pholcodine → International Drug Names
ATC code · 1
Pholcodine → R05DA08 (WHO)
Bioavailability · 1
Pholcodine → Maximum plasma conc. attained 4-8 hours after oral dose.

Important terminology Word statistics

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Important terminology

anaphylaxis 2023 drug administration products medicines liver anaesthesia effects general use nmbas risk european cough withdrawn agency dose uk containing

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Pholcodine3D model (JSmol)Interactive image1.00infobox
PholcodineAddiction liabilityHigh1.00infobox
PholcodineAHFS/Drugs.comInternational Drug Names1.00infobox
PholcodineATC codeR05DA08 (WHO)1.00infobox
PholcodineBioavailabilityMaximum plasma conc. attained 4-8 hours after oral dose.1.00infobox
PholcodineCAS Number509-67-11.00infobox
PholcodineChEBICHEBI:535791.00infobox
PholcodineChEMBLChEMBL21052241.00infobox
PholcodineChemSpider44708541.00infobox
PholcodineCompTox Dashboard (EPA)DTXSID701989231.00infobox
PholcodineDrugBankDB092091.00infobox
PholcodineECHA InfoCard100.007.3671.00infobox
PholcodineElimination half-life32-43 hours; volume of distribution is 36-49L/kg.1.00infobox
PholcodineExcretionKidney1.00infobox
PholcodineFormulaC23H30N2O41.00infobox
PholcodineKEGGD073851.00infobox
PholcodineLegal statusBR: Class A2 (Narcotic drugs)1.00infobox
PholcodineLegal statusCA: Schedule I1.00infobox
PholcodineLegal statusDE: Anlage II (Authorized trade only, not prescriptible)1.00infobox
PholcodineLegal statusUK: Class B1.00infobox
PholcodineLegal statusUS: Schedule I1.00infobox
PholcodineMetabolismLiver1.00infobox
PholcodineMolar mass398.503 g·mol−11.00infobox
PholcodineProtein binding23.5%1.00infobox
PholcodinePubChem CID53113561.00infobox
PholcodineRoutes of administrationBy mouth1.00infobox
PholcodineTrade namesLogicin, others1.00infobox
PholcodineUNIILPP64AWZ7L1.00infobox
Pholcodinecausesproduction of antibodies linked with fatalities during surgery0.90text
Pholcodineis aopioid cough suppressant0.90text

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