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Phase variation

In biology, phase variation is a method for dealing with rapidly varying environments without requiring random mutation. It involves the variation of protein expression, frequently in an on-off fashion, within different parts of a bacterial population. As such the phenotype can switch at frequencies that are much higher (sometimes >1%) than classical…

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Slipped strand mispairing

Slipped strand mispairingDNA synthesisRecADNA replicationDNA repair
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Site-specific recombination

RecombinaseGene productSalmonella enterica serovar TyphimuriumLeucineTransposition
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Epigenetic modification – methylation

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Nested DNA inversion

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Topics to explore

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Overview

Site-specific recombination

Gene conversion

Epigenetic modification – methylation

Nested DNA inversion

Slipped strand mispairing

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Map overview Semantic statistics

Phase variation

Nodes32
Edges31
Triples44
Avg. degree1.94
Density0.0625
Components1

How this topic connects Entity context

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Phase variation

Top relations

related to Insertion-excision · 16
Phase variation → Another, DNA, H1, H2, If, In, IS492, MooV, OFF, ON, Once, Phase, Piv, Salmonella Typhimurium, Two, When IS492
related to Epigenetic modification – methylation · 14
Phase variation → Ag43, Agn43, An, Antigen, Dam, DNA, DNA-methylating, GATC, OxyR, The, The ON, Unlike, When, When OxyR
related to Gene conversion · 9
Phase variation → Gene, Neisseria, Pil, PilE, PilS, The, There, This, Type IV
related to Nested DNA inversion · 4
Phase variation → Campylobacter, In, The, This
is a · 1
Phase variation → method for dealing with rapidly varying environments without requiring random mutation

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Important terminology

gene expression promoter phase variation dna protein different sequence sequences short transcription repeat one binding types inversion salmonella region ssm

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Phase variationis amethod for dealing with rapidly varying environments without requiring random mutation0.90text
Phase variationrelated to Epigenetic modification – methylationUnlike0.60section
Phase variationrelated to Epigenetic modification – methylationDNA0.60section
Phase variationrelated to Epigenetic modification – methylationThe0.60section
Phase variationrelated to Epigenetic modification – methylationAn0.60section
Phase variationrelated to Epigenetic modification – methylationAntigen0.60section
Phase variationrelated to Epigenetic modification – methylationAg430.60section
Phase variationrelated to Epigenetic modification – methylationDNA-methylating0.60section
Phase variationrelated to Epigenetic modification – methylationDam0.60section
Phase variationrelated to Epigenetic modification – methylationOxyR0.60section
Phase variationrelated to Epigenetic modification – methylationAgn430.60section
Phase variationrelated to Epigenetic modification – methylationWhen OxyR0.60section

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