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PGRMC1

Progesterone receptor membrane component 1 (abbreviated PGRMC1) is a protein which co-purifies with progesterone binding proteins in the liver and ovary. In humans, the PGRMC1 protein is encoded by the PGRMC1 gene.

Binding to heme and cytochrome P450s, Expression & Roles in signaling and apoptosis

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Binding to heme and cytochrome P450s

7 related topics

Expression

5 related topics

Roles in signaling and apoptosis

4 related topics

Overview

6 related topics

Key facts & relationships

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Aliases
PGRMC1, HPR6.6, MPR, progesterone receptor membrane component 1, Dap1, IZA, 25-Dx
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4X8Y
Band
Xq24 · X|X A3.3
Bgee
seminal vesicula · caput epididymis · corpus epididymis · tail of epididymis · bronchial epithelial cell
BioGPS
More reference expression data
Chr.
X chromosome (human) · X chromosome (mouse)

Topics to explore

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Overview

Expression

Binding to heme and cytochrome P450s

Roles in signaling and apoptosis

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Map overview Semantic statistics

PGRMC1

Nodes27
Edges26
Triples113
Avg. degree1.93
Density0.074074
Components1

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PGRMC1

Top relations

Gene ontology · 22
PGRMC1 → amyloid-beta binding, cell body, endomembrane system, endoplasmic reticulum, endoplasmic reticulum membrane, extracellular exosome, heme binding, integral component of membrane, integral component of plasma membrane, intracellular membrane-bounded organelle, lipid binding, membrane, neuron projection, neutrophil degranulation, organelle membrane, plasma membrane, protein binding, smooth endoplasmic reticulum membrane, soma, specific granule membrane
Bgee · 20
PGRMC1 → anterior amygdaloid area, arcuate nucleus, bronchial epithelial cell, caput epididymis, corpus epididymis, dorsomedial hypothalamic nucleus, endometrium, lateral septal nucleus, left lobe of liver, middle temporal gyrus, olfactory epithelium, paraventricular nucleus of hypothalamus, pars compacta, pons, seminal vesicula, skin of thigh, suprachiasmatic nucleus, tail of epididymis, transitional epithelium of urinary bladder, ventromedial nucleus
RNA expression pattern · 20
PGRMC1 → anterior amygdaloid area, arcuate nucleus, bronchial epithelial cell, caput epididymis, corpus epididymis, dorsomedial hypothalamic nucleus, endometrium, lateral septal nucleus, left lobe of liver, middle temporal gyrus, olfactory epithelium, paraventricular nucleus of hypothalamus, pars compacta, pons, seminal vesicula, skin of thigh, suprachiasmatic nucleus, tail of epididymis, transitional epithelium of urinary bladder, ventromedial nucleus
related to Binding to heme and cytochrome P450s · 18
PGRMC1 → As, Cyp21, CYP21A2, CYP3A4, Cyp51-catalyzed, CYP51A1, CYP7A1, Dap1, DNA, Erg11, Erg11/Cyp51, In, Just, P450, The PGRMC1, This, Thus, Yeast
related to Roles in signaling and apoptosis · 8
PGRMC1 → Akt, However, In, IκB, PAIR-BP1, Progesterone, RNA-binding, The
Band · 2
PGRMC1 → Xq24, X|X A3.3
Chr. · 2
PGRMC1 → X chromosome (human), X chromosome (mouse)
End · 2
PGRMC1 → 119,244,466 bp, 35,869,732 bp
related to Expression · 2
PGRMC1 → In, Microarray
Aliases · 1
PGRMC1 → PGRMC1, HPR6.6, MPR, progesterone receptor membrane component 1, Dap1, IZA, 25-Dx

Important terminology Word statistics

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Important terminology

protein gene progesterone human expression binding bp proteins also dap1 chr band yeast binds membrane liver cells component chromosome receptor

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
PGRMC1AliasesPGRMC1, HPR6.6, MPR, progesterone receptor membrane component 1, Dap1, IZA, 25-Dx1.00infobox
PGRMC1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4X8Y1.00infobox
PGRMC1BandXq241.00infobox
PGRMC1BandX|X A3.31.00infobox
PGRMC1Bgeeseminal vesicula1.00infobox
PGRMC1Bgeecaput epididymis1.00infobox
PGRMC1Bgeecorpus epididymis1.00infobox
PGRMC1Bgeetail of epididymis1.00infobox
PGRMC1Bgeebronchial epithelial cell1.00infobox
PGRMC1Bgeepons1.00infobox
PGRMC1Bgeeendometrium1.00infobox
PGRMC1Bgeeskin of thigh1.00infobox
PGRMC1Bgeemiddle temporal gyrus1.00infobox
PGRMC1Bgeepars compacta1.00infobox
PGRMC1Bgeeolfactory epithelium1.00infobox
PGRMC1Bgeetransitional epithelium of urinary bladder1.00infobox
PGRMC1Bgeeparaventricular nucleus of hypothalamus1.00infobox
PGRMC1Bgeearcuate nucleus1.00infobox
PGRMC1Bgeeventromedial nucleus1.00infobox
PGRMC1Bgeesuprachiasmatic nucleus1.00infobox
PGRMC1Bgeeanterior amygdaloid area1.00infobox
PGRMC1Bgeelateral septal nucleus1.00infobox
PGRMC1Bgeeleft lobe of liver1.00infobox
PGRMC1Bgeedorsomedial hypothalamic nucleus1.00infobox
PGRMC1BioGPSMore reference expression data1.00infobox
PGRMC1Chr.X chromosome (human)1.00infobox
PGRMC1Chr.X chromosome (mouse)1.00infobox
PGRMC1DatabasesNCBI: entry; OMA: entry1.00infobox
PGRMC1End119,244,466 bp1.00infobox
PGRMC1End35,869,732 bp1.00infobox

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