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Penams are the primary skeleton structures that define the penicillin subclass of the broader β-lactam family of antibiotics and related compounds. They are bicyclic ring systems containing a β-lactam moiety fused with a five-member thiazolidine ring. Due to ring strain and limitations on amide resonance, the structure is unstable and highly susceptible…
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bond structure β-lactam penams ring penicillin due strain related compounds amide resonance references c-n structures susceptible standard state antibiotics moiety
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Penam | related to Structure | Penams | 0.60 | section |
| Penam | related to Structure | The | 0.60 | section |
| Penam | related to Structure | C-N | 0.60 | section |
| Penam | related to Structure | As | 0.60 | section |
| Penam | related to Structure | The C-O | 0.60 | section |
| Penam | related to Structure | C-O | 0.60 | section |
| Penam | related to Structure | Consequently | 0.60 | section |
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Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.