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PCLO

Protein piccolo is a protein that in humans is encoded by the PCLO gene.

Function, Interactions & Clinical relevance

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Function

3 related topics

Interactions

2 related topics

Clinical relevance

1 related topics

Overview

2 related topics

Key facts & relationships

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Aliases
PCLO, ACZ, PCH3, piccolo presynaptic cytomatrix protein
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1UJD
Band
7q21.11 · 5|5 A1- A2
Bgee
Brodmann area 23 · middle temporal gyrus · cerebellar vermis · orbitofrontal cortex · Region I of hippocampus proper
BioGPS
More reference expression data
Chr.
Chromosome 7 (human) · Chromosome 5 (mouse)

Topics to explore

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Overview

Function

Interactions

Clinical relevance

Advanced semantic analysis

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Map overview Semantic statistics

PCLO

Nodes13
Edges12
Triples114
Avg. degree1.85
Density0.153846
Components1

How this topic connects Entity context

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PCLO

Top relations

Gene ontology · 24
PCLO → calcium ion binding, calcium-dependent phospholipid binding, cAMP-mediated signaling, cell junction, cytoskeleton, cytoskeleton of presynaptic active zone, cytoskeleton organization, extracellular exosome, insulin secretion, maintenance of presynaptic active zone structure, membrane, metal ion binding, postsynaptic density, presynapse to nucleus signaling pathway, presynaptic active zone, presynaptic active zone cytoplasmic component, profilin binding, protein localization to synapse, regulation of exocytosis, structural constituent of presynaptic active zone
Bgee · 20
PCLO → amygdala, Brodmann area 23, Brodmann area 46, cerebellar vermis, cingulate gyrus, endothelial cell, entorhinal cortex, frontal pole, medial dorsal nucleus, middle temporal gyrus, olfactory tubercle, orbitofrontal cortex, piriform cortex, prefrontal cortex, primary motor cortex, Region I of hippocampus proper, subiculum, superior cervical ganglion, superior frontal gyrus, temporal lobe
RNA expression pattern · 20
PCLO → amygdala, Brodmann area 23, Brodmann area 46, cerebellar vermis, cingulate gyrus, endothelial cell, entorhinal cortex, frontal pole, medial dorsal nucleus, middle temporal gyrus, olfactory tubercle, orbitofrontal cortex, piriform cortex, prefrontal cortex, primary motor cortex, Region I of hippocampus proper, subiculum, superior cervical ganglion, superior frontal gyrus, temporal lobe
related to Function · 13
PCLO → Among, Bassoon, BSN, MIM, Oboe, OMIM, PCM, Piccolo, RIM, RIMS1, RIMS2, Synaptic, The
related to Interactions · 9
PCLO → Abp1, DAAM1, F-actin-binding, GIT1, Piccolo, PRA1, Profilin, The, TRIO
related to Clinical relevance · 5
PCLO → B-cell, III, PCH3, Recent, Recurrent
Band · 2
PCLO → 5|5 A1- A2, 7q21.11
Chr. · 2
PCLO → Chromosome 5 (mouse), Chromosome 7 (human)
End · 2
PCLO → 14,913,473 bp, 83,162,930 bp
Aliases · 1
PCLO → PCLO, ACZ, PCH3, piccolo presynaptic cytomatrix protein

Important terminology Word statistics

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Important terminology

bp gene chr protein human band chromosome piccolo synaptic location presynaptic mouse active zone function external pdb uniprot q9y6v0 vesicles

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
PCLOAliasesPCLO, ACZ, PCH3, piccolo presynaptic cytomatrix protein1.00infobox
PCLOAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1UJD1.00infobox
PCLOBand7q21.111.00infobox
PCLOBand5|5 A1- A21.00infobox
PCLOBgeeBrodmann area 231.00infobox
PCLOBgeemiddle temporal gyrus1.00infobox
PCLOBgeecerebellar vermis1.00infobox
PCLOBgeeorbitofrontal cortex1.00infobox
PCLOBgeeRegion I of hippocampus proper1.00infobox
PCLOBgeeendothelial cell1.00infobox
PCLOBgeefrontal pole1.00infobox
PCLOBgeeentorhinal cortex1.00infobox
PCLOBgeeBrodmann area 461.00infobox
PCLOBgeesuperior frontal gyrus1.00infobox
PCLOBgeecingulate gyrus1.00infobox
PCLOBgeeprimary motor cortex1.00infobox
PCLOBgeeprefrontal cortex1.00infobox
PCLOBgeesubiculum1.00infobox
PCLOBgeemedial dorsal nucleus1.00infobox
PCLOBgeetemporal lobe1.00infobox
PCLOBgeeamygdala1.00infobox
PCLOBgeesuperior cervical ganglion1.00infobox
PCLOBgeeolfactory tubercle1.00infobox
PCLOBgeepiriform cortex1.00infobox
PCLOBioGPSMore reference expression data1.00infobox
PCLOChr.Chromosome 7 (human)1.00infobox
PCLOChr.Chromosome 5 (mouse)1.00infobox
PCLODatabasesNCBI: entry; OMA: entry1.00infobox
PCLOEnd83,162,930 bp1.00infobox
PCLOEnd14,913,473 bp1.00infobox

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