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Protein piccolo is a protein that in humans is encoded by the PCLO gene.
The analysis highlights Function, Interactions and Clinical relevance as prominent areas in the source structure around PCLO.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around PCLO shows recurring relationship patterns in the source. For example, PCLO → calcium ion binding, calcium-dependent phospholipid binding, cAMP-mediated signaling, cell junction, cytoskeleton, cytoskeleton of presynaptic active zone, cytoskeleton organization, extracellular exosome, insulin secretion, maintenance of presynaptic active zone structure, membrane, metal ion binding, postsynaptic density, presynapse to nucleus signaling pathway, presynaptic active zone, presynaptic active zone cytoplasmic component, profilin binding, protein localization to synapse, regulation of exocytosis, structural constituent of presynaptic active zone Another extracted example is PCLO → amygdala, Brodmann area 23, Brodmann area 46, cerebellar vermis, cingulate gyrus, endothelial cell, entorhinal cortex, frontal pole, medial dorsal nucleus, middle temporal gyrus, olfactory tubercle, orbitofrontal cortex, piriform cortex, prefrontal cortex, primary motor cortex, Region I of hippocampus proper, subiculum, superior cervical ganglion, superior frontal gyrus, temporal lobe. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
bp gene chr protein human band chromosome piccolo synaptic location presynaptic mouse active zone function external pdb uniprot q9y6v0 vesicles
TTTA extracted 114 structured relationships around PCLO. Examples in this analysis include PCLO → Aliases → PCLO, ACZ, PCH3, piccolo presynaptic cytomatrix protein and PCLO → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1UJD. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| PCLO | Aliases | PCLO, ACZ, PCH3, piccolo presynaptic cytomatrix protein | 1.00 | infobox |
| PCLO | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1UJD | 1.00 | infobox |
| PCLO | Band | 7q21.11 | 1.00 | infobox |
| PCLO | Band | 5|5 A1- A2 | 1.00 | infobox |
| PCLO | Bgee | Brodmann area 23 | 1.00 | infobox |
| PCLO | Bgee | middle temporal gyrus | 1.00 | infobox |
| PCLO | Bgee | cerebellar vermis | 1.00 | infobox |
| PCLO | Bgee | orbitofrontal cortex | 1.00 | infobox |
| PCLO | Bgee | Region I of hippocampus proper | 1.00 | infobox |
| PCLO | Bgee | endothelial cell | 1.00 | infobox |
| PCLO | Bgee | frontal pole | 1.00 | infobox |
| PCLO | Bgee | entorhinal cortex | 1.00 | infobox |
| PCLO | Bgee | Brodmann area 46 | 1.00 | infobox |
| PCLO | Bgee | superior frontal gyrus | 1.00 | infobox |
| PCLO | Bgee | cingulate gyrus | 1.00 | infobox |
| PCLO | Bgee | primary motor cortex | 1.00 | infobox |
| PCLO | Bgee | prefrontal cortex | 1.00 | infobox |
| PCLO | Bgee | subiculum | 1.00 | infobox |
| PCLO | Bgee | medial dorsal nucleus | 1.00 | infobox |
| PCLO | Bgee | temporal lobe | 1.00 | infobox |
| PCLO | Bgee | amygdala | 1.00 | infobox |
| PCLO | Bgee | superior cervical ganglion | 1.00 | infobox |
| PCLO | Bgee | olfactory tubercle | 1.00 | infobox |
| PCLO | Bgee | piriform cortex | 1.00 | infobox |
| PCLO | BioGPS | More reference expression data | 1.00 | infobox |
| PCLO | Chr. | Chromosome 7 (human) | 1.00 | infobox |
| PCLO | Chr. | Chromosome 5 (mouse) | 1.00 | infobox |
| PCLO | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| PCLO | End | 83,162,930 bp | 1.00 | infobox |
| PCLO | End | 14,913,473 bp | 1.00 | infobox |
The concept neighborhoods around PCLO bring nearby vocabulary together. In this analysis, examples include Protein, Piccolo and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For PCLO, one of the stronger structural bridges in this analysis connects PCLO with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around PCLO to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Clinical relevance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — PCLO · EN edition · Analysis: TopicsToTalkAbout