PAX2

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Explore the main themes, entities and connections around PAX2. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Function

Paired box Transcription factor WT1 MHB organizer

4 related topics

Clinical significance

Colobomas Renal hypoplasia Alternative splicing

3 related topics

Interactions

Interact PAXIP1

2 related topics

Overview

Protein Gene

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: PAX2, PAPRS, FSGS7, paired box 2, PAX-2
Band: 10q24.31 · 19 C3|19 38.09 cM
Bgee: renal medulla · right uterine tube · human kidney · tail of epididymis · corpus epididymis
BioGPS: More reference expression data
Chr.: Chromosome 10 (human) · Chromosome 19 (mouse)
Databases: NCBI: entry; OMA: entry

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Function

Paired box Pax genes
Transcription factor
WT1
MHB organizer Isthmic Organizer

Clinical significance

Interactions

Interact Protein-protein interaction
PAXIP1

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes16

Edges15

Triples193

Avg. degree1.88

Density0.125

Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

PAX2

Top relations

Gene ontology · 85

PAX2 → ageing, animal organ development, axonogenesis, brain morphogenesis, branching involved in ureteric bud morphogenesis, camera-type eye development, cell differentiation, cell fate determination, cellular response to epidermal growth factor stimulus, cellular response to glucose stimulus, cellular response to hydrogen peroxide, cellular response to retinoic acid, centriolar satellite, cis-regulatory region sequence-specific DNA binding, cochlea development, cochlea morphogenesis, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, glial cell differentiation

related to Function · 30

PAX2 → Concentration, DNA-binding, Drosophila, En, En1, Expression, Family, FGF8, In, It, Member, Mesencephalon, MHB, MHB-specific, Otx2-Gbx2, Paired-Box Containing Genes, Pax, Pax-2, Pax5, Pax8

Bgee · 20

PAX2 → corpus epididymis, endometrium, epithelium of epididymis, Gray matter of spinal cord, human kidney, kidney tubule, mesonephric duct, mesonephric tubules, mesonephros, neural ectoderm, optic recess, optic stalk, otic placode, paraflocculus of cerebellum, renal medulla, right uterine tube, seminal vesicula, tail of epididymis, testicle, ureteric bud

RNA expression pattern · 20

related to External links · 8

PAX2 → GeneReviews/NCBI/NIH/UW, Medicine, Medicine Medical Subject Headings, MeSH, National Library, Renal Coloboma SyndromePAX2, This, United States National Library

related to Clinical significance · 7

PAX2 → Alternative, Gata3, HGF, Mutations, Pathologically, Pax8, Without

Band · 2

PAX2 → 10q24.31, 19 C3|19 38.09 cM

Chr. · 2

PAX2 → Chromosome 10 (human), Chromosome 19 (mouse)

End · 2

PAX2 → 100,829,944 bp, 44,837,871 bp

is a · 2

PAX2 → attractive therapeutic target and a number of methods for inhibiting its activity have been investigated, earliest known gene to be expressed across the Otx2-Gbx2 boundary

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene human bp transcription factor chr band expression development chromosome 10 also kidney expressed system paired box protein renal region

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
PAX2	Aliases	PAX2, PAPRS, FSGS7, paired box 2, PAX-2	1.00	infobox
PAX2	Band	10q24.31	1.00	infobox
PAX2	Band	19 C3\|19 38.09 cM	1.00	infobox
PAX2	Bgee	renal medulla	1.00	infobox
PAX2	Bgee	right uterine tube	1.00	infobox
PAX2	Bgee	human kidney	1.00	infobox
PAX2	Bgee	tail of epididymis	1.00	infobox
PAX2	Bgee	corpus epididymis	1.00	infobox
PAX2	Bgee	seminal vesicula	1.00	infobox
PAX2	Bgee	endometrium	1.00	infobox
PAX2	Bgee	testicle	1.00	infobox
PAX2	Bgee	paraflocculus of cerebellum	1.00	infobox
PAX2	Bgee	kidney tubule	1.00	infobox
PAX2	Bgee	mesonephros	1.00	infobox
PAX2	Bgee	mesonephric tubules	1.00	infobox
PAX2	Bgee	mesonephric duct	1.00	infobox
PAX2	Bgee	optic stalk	1.00	infobox
PAX2	Bgee	ureteric bud	1.00	infobox
PAX2	Bgee	otic placode	1.00	infobox
PAX2	Bgee	neural ectoderm	1.00	infobox
PAX2	Bgee	epithelium of epididymis	1.00	infobox
PAX2	Bgee	Gray matter of spinal cord	1.00	infobox
PAX2	Bgee	optic recess	1.00	infobox
PAX2	BioGPS	More reference expression data	1.00	infobox
PAX2	Chr.	Chromosome 10 (human)	1.00	infobox
PAX2	Chr.	Chromosome 19 (mouse)	1.00	infobox
PAX2	Databases	NCBI: entry; OMA: entry	1.00	infobox
PAX2	End	100,829,944 bp	1.00	infobox
PAX2	End	44,837,871 bp	1.00	infobox
PAX2	Ensembl	ENSG00000075891	1.00	infobox

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Connections between topic areas Semantic bridges

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