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Osteogenesis imperfecta

Osteogenesis imperfecta (.mw-parser-output .IPA-label-small{font-size:85%}.mw-parser-output .references .IPA-label-small,.mw-parser-output .infobox .IPA-label-small,.mw-parser-output .navbox .IPA-label-small{font-size:100%}IPA: /ˌɒstioʊˈdʒɛnəsɪs ˌɪmpɜːrˈfɛktə/; OI), colloquially known as brittle bone disease, is a group of genetic disorders that all…

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Causes
Genetic (autosomal dominant or de novo mutation)
Diagnostic method
Based on symptoms, DNA testing
Duration
Long term
Frequency
1 in 15,000–20,000 people
Management
Healthy lifestyle (exercise, no smoking), metal rods through the long bones
Medication
Bisphosphonates

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Overview

Signs and symptoms

Classification

Genetics

Pathophysiology

Diagnosis

Treatment

Prevention

Prognosis

Epidemiology

History

Other animals

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Map overview Semantic statistics

Osteogenesis imperfecta

Nodes422
Edges421
Triples178
Avg. degree2
Density0.004739
Components1

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Osteogenesis imperfecta

Top relations

related to Of its classification · 24
Osteogenesis imperfecta → Alison Senn, Before, Classification, Congenita, Constitutional Disorders, David Danks, David Sillence, German, II, III, In, INCDS, International Nomenclature Group, IV, Journal, Looser, Martin Benno Schmidt, Medical Genetics, OI, Roy Morello
related to Of the term · 14
Osteogenesis imperfecta → Baljet, Dutch, Human, II, Illustrations, Included, Latin, Mammalian Embryogenesis, Museum Vrolikianum, OI, The, Vrolik, Vrolik's, Willem Vrolik
related to Orthopedic · 12
Osteogenesis imperfecta → Child Health, Danlos, Ehlers, Endocrine Unit, Fractures, In, Joint, Karachi, National Institute, OI, Pakistan, The
related to Differential diagnosis · 11
Osteogenesis imperfecta → Alice Velasquez, An, Bruck, Danlos, Differentiating, Ehlers, OI, Other, This, United States, Various
related to Epidemiology · 11
Osteogenesis imperfecta → An, Denmark, II, III, In, IV, OI, Sweden, The, Type, United States
related to External links · 11
Osteogenesis imperfecta → Archived, Department, Health, Human Services, May, National Institutes, National Resource Center, NIH Osteoporosis, October, Osteogenesis Imperfecta Overview, Related Bone Diseases
has prevention · 9
Osteogenesis imperfecta → As, Common, Genetic, If, Mendelian, OI, Patients, Those, Without
related to Genetics · 8
Osteogenesis imperfecta → Approximately, COL1A1, COL1A2, OI, Osteogenesis, The, There, These
has treatment · 7
Osteogenesis imperfecta → Judging, Maintaining, Norwegian, OI, There, Treatment, While
related to Genetic testing · 7
Osteogenesis imperfecta → COL1A1, COL1A2, Duplication, IFITM5, OI, The, To

Important terminology Word statistics

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Important terminology

oi type types may bone iii imperfecta genetic bones collagen mutations fractures severe iv cases cause patients osteogenesis also surgery

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Osteogenesis imperfectaCausesGenetic (autosomal dominant or de novo mutation)1.00infobox
Osteogenesis imperfectaDiagnostic methodBased on symptoms, DNA testing1.00infobox
Osteogenesis imperfectaDurationLong term1.00infobox
Osteogenesis imperfectaFrequency1 in 15,000–20,000 people1.00infobox
Osteogenesis imperfectaManagementHealthy lifestyle (exercise, no smoking), metal rods through the long bones1.00infobox
Osteogenesis imperfectaMedicationBisphosphonates1.00infobox
Osteogenesis imperfectaOnsetBirth1.00infobox
Osteogenesis imperfectaOther namesBrittle bone disease, Lobstein syndrome,: 5 fragilitas ossium, Vrolik disease,: 5 osteopsathyrosis idiopathica: 3471.00infobox
Osteogenesis imperfectaPreventionPre-implantation genetic diagnosis1.00infobox
Osteogenesis imperfectaPrognosisDepends on the type1.00infobox
Osteogenesis imperfectaPronunciation/ˌɒstioʊˈdʒɛnəsɪs ˌɪmpɜːrˈfɛktə/ OSS-tee-oh-JEN-ə-siss IM-pur-FEK-tə1.00infobox
Osteogenesis imperfectaSpecialtyPediatrics, medical genetics, orthopedics1.00infobox
Osteogenesis imperfectaSymptomsBones that break easily, blue tinge to the sclera (whites of the eye), short height, joint hypermobility, hearing loss1.00infobox

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